Curriculum Vitae

Michael Joseph Kuhar

 8/1/2015

 

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Address:

Yerkes National Primate Research Center of Emory University

Division of Behavioral Neuroscience and Psychiatric Disorders

954 Gatewood Rd. NE

Atlanta, GA  30329

Phone:  (404) 727‑3274

e-mail:  mkuhar@rmy.emory.edumkuhar@emory.eduMichael.Kuhar@emory.edu

Web site:  www.michaeljkuhar.com

 

Education:

1965, B.S., University of Scranton

Scranton, Pennsylvania, Departments of

Physics and Philosophy, Magna cum Laude

 

1970, Ph.D., The Johns Hopkins University

Baltimore, Maryland, Departments of Biophysics and Pharmacology

 

Present Positions:

November 1995-present, Professor, Emory University

Charles Howard Candler Professor of Neuropharmacology

Georgia Research Alliance Eminent Scholar

Center for Ethics, Senior Fellow

Division of Behavioral Neuroscience and Psychiatric Disorders

(Chief of the Neuroscience Division, 1995-2010)

Yerkes National Primate Research Center of Emory University,

Department of Pharmacology, Emory University School of Medicine

 

Previous Positions:

July 1985‑November 1995

Chief, Neuroscience Branch, Addiction Research Center, National Institute on Drug Abuse

 

Professor, Part‑time, The Johns Hopkins University School of Medicine

Departments of Neuroscience, Pharmacology and Psychiatry

 

July 1981, Professor, The Johns Hopkins University School of Medicine

Departments of Neuroscience, Pharmacology and Psychiatry

 

July 1980, Associate Professor, The Johns Hopkins University School of Medicine

Departments of Neuroscience, Pharmacology and Psychiatry

 

July 1976, Associate Professor, The Johns Hopkins University School of Medicine

Departments of Pharmacology and Psychiatry

 

October 1972, Assistant Professor, The Johns Hopkins University School of Medicine

Departments of Pharmacology and Psychiatry

 

October 1970, Postdoctoral Fellow, Yale University School of Medicine

Department of Psychiatry and Basic Biological Sciences

 

Societies:

  • American Association for the Advancement of Science (1969‑present)
  • Society for Neuroscience (1973‑present; Nominating Committee, 1984‑1987; Presidential Symposium Speaker, 1990; Public Information Committee, 1996-1999; Social Issues Committee, 2003-2006; President, Atlanta Chapter, 2003-2004)
  • American Society for Neurochemistry (1973‑1983; Program Committee, 1978; Organizer of Symposium on Neural Peptides, 1978)
  • American Society for Pharmacology and Experimental Therapeutics (1974‑present; 2014 – present, Emeritus,  Symposium Organizer at International Meeting, 1984; Selection Committee for Otto Krayer Award, 1993, 1997, 2002; and Neuropharmacology Division Executive Committee, 2002-2005, and Chair, 2003-2004; John Jacob Abel Award Committee, 2004-2007; Program Committee, 2006-2008; Neuropharmacology Division Nominating Committee, 2007)
  • Mid‑Atlantic Acetylcholine Discussion Group (1973‑1978; Co‑Chairman, 1975)
  • American College of Neuropsychopharmacology (Scientific Associate, 1978; Member, 1980; Fellow,
  • 1986‑2013; Member of Education and Training Committee, 1984‑1987; Program Committee,
  • 1988‑1990; Ethics Committee, 1991‑1993; Credentials Committee, 1993-1995; Animals in Research
  • Committee, 2001-2004; Emeritus, 2013- present)
  • International Brain Research Organization (IBRO) (1979‑present)
  • International Drug Abuse Research Society (IDARS) (Member 2004; President, 2004-2008)
  • College on Problems of Drug Dependence, Inc. (Member, 1994; Board of Directors, 1994-1998; Fellow, 1998; Executive Committee, 1999-2001; President, 1999-2000; Nominating Committee, 1994-1995; Publications Committee, 1994-1995; Media Relations Committee, Chair, 1994-1997; Long-Range Planning Committee, 2001-2004; Media Committee, 2001-2007; ONDCP Task Force, 2001-2003; Program Committee, 2013-2016)
  • Neuroethics Society (2007 – present)

 

Professional Honors and Other Experience:

  • Phi Beta Kappa (1970)
  • National Institute of Mental Health Research Career Development Award, Type II (3/1/75 ‑ renewed 3/1/80 and 3/1/85)
  • National Institute of Mental Health Small Grants Committee (9/1/77‑8/31/81)
  • Distinguished Young Scientist in Maryland Award (1977; The Maryland Academy of Sciences)
  • Visiting Scientist, National Institute for Medical Research, Mill Hill, London (Summer 1978; Molecular Pharmacology Unit, A.S.V. Burgen, Director)
  • Consultant, Pharmacology Department, Hoffman‑La Roche, 1980‑1985
  • Grass Traveling Scientist, Spring 1981, to Halifax, Nova Scotia
  • Listed among “1,000 Contemporary Scientists Most Cited 1965‑1978”, Current Contents 24, 5, 1981
  • Daniel H. Efron Award (1984, from the American College of Neuropsychopharmacology)
  • Mathilde Solowey Award for Research in Neuroscience, (1985 from the Foundation for Advanced
  • Education in the Sciences)
  • First Ariens Lecture (1985, The Dutch Pharmacological Society; DUPHAR)
  • Family Therapy Institute of Washington, DC, Part-time Family Therapy Training, 1983-1985.
  • Jay Haley and Cloe Madanes, Supervisors.  276 individual and group supervision hours.
  • Graduate Certificate in Substance Abuse Counseling, 1988, Loyola University
  • Sterling Lecture (1987, Tufts Univ. School of Medicine; 1988, University of Kentucky Medical School)
  • Gold Lecture on Substance Abuse (1988, University of Florida Medical School at Gainesville)
  • Senior Executive Service Appointment (November 20, 1988, Dept. of Health & Human Services)
  • Administrator’s Award for Meritorious Achievement (1989, ADAMHA)
  • Upjohn Lecture (1989, Uniformed Services University of the Health Sciences)
  • Thomas L. O’Donohue Memorial Lecture (1989, Howard University)
  • Ross McIntyre Award (1990, University of Nebraska Medical Center)
  • Presidential Symposium Lecturer (1990, Society for Neuroscience)
  • First Ivan F.W. Davidson Memorial Lecture (1990, Bowman Gray School of Medicine)
  • Distinguished Lecturer (1992, Stritch School of Medicine)
  • Otto Krayer Award (1992, American Society for Pharmacology and Experimental Therapeutics)
  • Harry Williams Lectureship Award (1992, Emory University School of Medicine)
  • Grass Lecture (1993, University of Kansas, MO)
  • Boots Distinguished Neuroscientist Lecture (1993, Louisiana State University Medical Center)
  • Visiting Committee, Medical Department (1993-1997, Brookhaven National Laboratory)
  • Consultant, Guilford Pharmaceuticals (1995)
  • Charles Howard Candler Professor (1995, Emory University)
  • Distinguished Lecturer (1996, University of South Alabama)
  • Eminent Scholar Award (1996, State of Georgia and Emory University)
  • The Dana Alliance, Member (1997-present)
  • Advisory Board, Addiction Studies Institute, Wale Forest University (1999-present)
  • President, College on Problems of Drug Dependence, Inc. (1999-2000)
  • Scientific Advisory Board, Amethyst Technologies (1999-2000)
  • Scientific Advisory Board, Addiction Therapies, Inc. (1999-2003)
  • NIDA K05 Senior Scientist Award (1999-2004; 2004-2009)
  • NIDA Special Emphasis Panels (member or chair, 1999-2008)
  • Listed (by ISI) among the 250 most cited scientists in Neuroscience from 1981-2000 (rank 23rd)
  • Scientific Advisory Board, Center for Psychiatric Neuroscience, University of Mississipppi Medical School (2000-2005)
  • Director, Institutional Training Program in Drug Abuse, Emory University (2003-present)
  • NIDA K Study Section (Ad hoc, 2003-2004; regular member, 2004-2008)
  • NIDA study sections, ad hoc member (2008 – present).
  • Board of Directors, Aptotec, Inc. (2004-2015)
  • International Drug Abuse Research Society (IDARS) [First President (2004-2008)]
  • External Advisory Board, Center of Research Excellence in Natural Products Neuroscience, University of Mississippi at Oxford (2006-present)
  • Wendy and Stanley Marsh Lecture in Substance Abuse and Addictive Disorders, Texas Tech University Health Sciences Center, 2007
  • Citations “h” index = 103, “m” index = 2.71 (in 2007).
  • Fulbright Award for Chile, South America (2008)
  • Teaching the Dalai Lama’s Tibetan Buddhist Monks and Nuns at Dharamsala, India, through the Emory-Tibet Science Intiative (2009-2011).
  • Nathan B Eddy Award (for lifetime achievement, 2011, College on Problems of Drug Dependence)
  • Journal of Drug and Alcohol Research, Ashdin Press, Editor-in-Chief, (2012-)
  • Board of Directors, Ethics in Bio-innovation. (2014 – )
  • Gregory Bagby Distinguished Mentor lecture, LSU Med Sch (New Orleans), Dept Physiol, 4/2015.
  • Advisory Board for PrayerSpark, Inc. (2015 – )

 

Editorial Boards (past and present):

  • Biochemical Pharmacology (2004-2013)
  • Brain Research (1980‑1989)
  • Current Molecular Pharmacology (2008- present)
  • Current Opinion in Central and Peripheral Nervous Systems (1998-2000)
  • Current Protocols in Pharmacology (1996-2001)
  • Drug and Alcohol Dependence (1995-2001)
  • Experimental and Clinical Psychopharmacology (1992-2000)
  • International Journal of Molecular Medicine (1997-2013)
  • Journal of Chemical Neuroanatomy (1987‑2000)
  • Journal of Drug and Alcohol Research, Editor-in-Chief (2012-2014)
  • Journal of Neurochemistry (1980‑1985)
  • Journal of Neuroscience (1983‑1989)
  • Journal of Pharmacology and Experimental Therapeutics (1993-2006)
  • Life Sciences (2003-2012)
  • Medical Hypotheses and Research (2003-2013)
  • Molecular and Cellular Neuroscience (1990-1995)
  • Neurobiology of Aging (1980‑1985)
  • NeuroImage (1991‑1995)
  • Neuropeptides (1980‑ present)
  • Neuropharmacology (1980‑1992)
  • Neuropsychopharmacology (1991‑1995)
  • Neuroscience-Net (1996- present)
  • Peptide Research (1989‑1994)
  • Peptides (2007- 2011)
  • Research Communications in Substances of Abuse (1991-1995)
  • Substance and Alcohol Misuse (1980-1985)
  • Synapse (1992‑2008)
  • Trends in Neuroscience (1982-1994)
  • The Open Ethics Journal (2007- 2011)
  • Substance Abuse: Research and Treatment (2007- present)

 

Seminar and Symposia Invitations:

  • Dr Kuhar has presented about 300 seminars, symposia lectures, and special and keynote lectures since 1972 when he became an Assistant Professor.

 

BOOKS AND VOLUMES (Edited)

  1. Yamamura, H.I., Enna, S.J., and Kuhar, M.J. (Eds.).  Neurotransmitter Receptor Binding.  Raven Press, New York, 1978.
  2. Pepeu, G.C., Kuhar, M.J., and Enna, S.J. (Eds.). Receptors for Neurotransmitters and Peptide Hormones. Adv. Biochem. Psychopharm., Vol. 21 (E. Costa and P. Greengard, Series Eds.).  Raven Press, New York, 1980.
  3. Kuhar, M.J. and Pasternak, G.W. (Eds.).  Analgesics: Pharmacological and Clinical Perspectives, Part of set in Neuropharmacology (S.J. Enna, Set Ed.).  Raven Press, New York, 1984.
  4. Yamamura, H.I., Enna, S.J., and Kuhar, M.J. (Eds.).  Neurotransmitter Receptor Binding, 2nd  Edition.  Raven Press, New York, 1985.
  5. Bjorklund, A., Hokfelt, T., and Kuhar, M.J. (Eds.).  Handbook of Chemical Neuroanatomy, Vol. 3, Classical Transmitters and Transmitter Receptors in the CNS Part II.   Elsevier North‑Holland Biomedical Press, Amsterdam, 1985.
  6. Yamamura, H.I., Enna, S.J., and Kuhar, M.J. (Eds.).  Methods in Neurotransmitter Receptor Analysis.  Raven Press, New York, 1990.
  7. Bjorklund, A., Hokfelt, T., and Kuhar, M.J. (Eds.).  Handbook of Chemical Neuroanatomy, Vol. 9, Neuropeptides in the CNS Part II.  Elsevier Press, Amsterdam, 1990.
  8. Rapaka, R.S., Makriyannis, A., and Kuhar, M.J. (Eds.).  Emerging Technologies and New Directions  in Drug Abuse Research, NIDA Research Monograph Series 112.  U.S. Government Printing Office, Washington, DC, 1991.
  9. Bjorklund, A., Hokfelt, T., and Kuhar, M.J. (Eds.).  Handbook of Chemical Neuroanatomy, Vol. 11, Neuropeptide Receptors in the CNS.  Elsevier Press, Amsterdam, 1992.
  10. Jaffe, J.H., Anthony, J.C., Johanson, C.-E., Kuhar, M.J., Moore, M.H., and E.M. Sellers (Eds.). Encyclopedia of Drugs and Alcohol.  Simon & Schuster Macmillan, New York, 1995.
  11. Schuster, C.R. and Kuhar, M.J. (Eds.). Pharmacological Aspects of Drug Dependence, Vol. 118, Handbook of Experimental Pharmacology.  Springer-Verlag, New York, 1996.
  12. Carson-DeWitt, R., Carroll, K.M., Fagan, J., Kranzler, H.R., and Kuhar, M.J. (Eds.). Encyclopedia of Drugs, Alcohol and Addictive Behavior, 2nd  Macmillan Reference USA, New York, 2001.
  13. Kuhar, M.J. and Pogun, S. (Eds.). Special Supplement Issue: Mathematical Modeling Mental Disorders and Processes.  Neuropsychopharmacology 28(Suppl. 1): 2003.
  14. Kuhar, M.J. (Editor of Special Issue on CART Peptides). Peptides, Vol. 27, August. 2006.
  15. Sibley, D.R., Hanin, I., Kuhar, M., and Skolnick, P. (Eds). Handbook of Contemporary Neuropharmacology, Vols. 1-3. John Wiley & Sons, Hoboken, NJ, 2007.
  16. Ali, S.F. and Kuhar, M.J. (Eds). Drug Addiction: Research Frontiers and Treatment Advances, Ann N Y Acad Sci, Vol 1139, 2008.
  17. Kranzler, HR and Korsmeyer, P (Eds). Kuhar MJ et al., (Assoc Eds.).  Encyclopedia of Drugs, Alcohol, and  Addictive Behavior,  3rd  MacMillan Reference USA, New York, 2009.
  18. Kuhar, MJ. The Addicted Brain: why we abuse drugs, alcohol and nicotine.  FT Press, Upper Saddle River, NJ, 2011.  ISBN-10: 0-13-254250-1.
  19. Kuhar, MJ. The Art and Ethics of Being a Good Colleague. CreateSpace Independent Publishing Platform. North Charleston, SC. 2013. ISBN-10: 1479359327.

 

PATENTS

  1. Carroll, F.I., Lewin, A.H., Abraham, P., Kuhar, M.J., and Boja, J.W. Cocaine Receptor Binding Ligands.  Patent Number: 5,128,118.  July 7, 1992.
  2. Uhl, G.R., Kuhar, M.J., Shimada, S., Kitayama, S., Patel, A., Lin, C.L. cDNA Encoding a Dopamine Transporter and Protein Encoded Thereby.  Patent Number: 5,312,734.  May 17, 1994.
  3. Kuhar, M.J., Boja, J.W., Carroll, F.I., Lewin, A.H., and Abraham, P. Cocaine Receptor Binding Ligands. Patent Number: 5,380,848.  January 10, 1995.
  4. Kuhar, M.J., Carroll, F.I., Boja, J.W., Lewin, A.H., and Abraham, P. Cocaine Receptor Binding Ligands. Patent Number: 5,413,779.  May 9, 1995.
  5. Kuhar, M.J., Carroll, F.I., Boja, J.W., Lewin, A.H., and Abraham, P. Cocaine Receptor Binding Ligands. Patent Number: 5,496,953.  March 5, 1996.
  6. Kuhar, M.J., Carroll, F.I., Boja, J.W., Lewin, A.H., and Abraham, P. Methods for Controlling Invertebrate Pests Using Cocaine Receptor Binding Ligands.  Patent Number: 5,935,953.  August 10, 1999.
  7. Carroll, F.I., Kuhar, M.J., Boja, J.W., Lewin, A.H., and Abraham, P. Cocaine Receptor Binding Ligands.  Patent Number: 6,329,520.  December 11, 2001.
  8. Kuhar, M.J., Carroll, F.I., Boja, J.W., Lewin, A.H., and Abraham, P. Dopamine Transporter Imaging Ligand.  Patent Number: 6,358,492.  March 19, 2002.
  9. Carroll, F.I., Kuhar, M.J., Boja, J.W., Lewin, A.H., and Abraham, P. Cocaine Receptor Binding Ligands. Patent Number: 6,531,483.  March 11, 2003.
  10. Carroll, F.I., Kuhar, M.J., Boja, J.W., Lewin, A.H., and Abraham, P. Cocaine Receptor Binding Ligands.  Patent Number 6,706,880 B2.  March 16, 2004.
  11. Kuhar, M.J., Carroll, F.I., Boja, J.W., Lewin, A.H., and Abraham, P. Cocaine Receptor Binding Ligands. Patent Number 7,011,813. March 14, 2006.

 

JOURNAL ARTICLES

  1. De Souza, E.B., Seifert, H., and Kuhar, M.J. Vasoactive Intestinal Peptide Receptor Localization in Rat Forebrain by Autoradiography.  Lett. 56: 113‑120, 1985.
  2. Whitehouse, P.J., Wamsley, J.K., Zarbin, M.A., Price D.L., and Kuhar, M.J. Neurotransmitter Receptors in Amyotrophic Lateral Sclerosis: Possible Relationship to Sparing of Eye Movements (Letter to the Editor).  Neurol. 17: 518, 1985.
  3. Inoue, Y., Wagner, H.N., Jr., Wong, D.F., Links, J.M., Frost, J.J., Dannals, R.F., Rosenbaum, A.E., Takeda, K., DiChiro, G., and Kuhar, M.J. Atlas of Dopamine Receptor Images (PET) of the Human Brain.  Comput. Assist. Tomogr. 9: 129‑140, 1985.
  4. Titeler, M., De Souza, E.B., and Kuhar, M.J. [3H]Nitrendipine Binding to Calcium Channels in Bovine and Rat Pituitary.  Neurochem. 44(6): 1955‑1958, 1985.
  5. Anholt, R.R.H., De Souza, E.B., Kuhar, M.J., and Snyder, S.H. Depletion of Peripheral‑Type Benzodiazepine Receptors after Hypophysectomy in Rat Adrenal Gland and Testis. J. Pharmacol. 110: 41‑46, 1985.
  6. De Souza, E.B., Perrin, M.H., Whitehouse, P.J., Rivier, J., Vale, W., and Kuhar. M.J. Corticotropin-Releasing Factor Receptors in Human Pituitary Gland: Autoradiographic Localization.  Neuroendo­crinology 40: 419‑422, 1985.
  7. Frost, J.J., Wagner, H.N., Jr., Dannals, R.F., Ravert, H.T., Links, J.M., Wilson, A.A., Burns, H.D., Wong, D.F., McPherson, R.W., Rosenbaum, A.E., Kuhar, M.J., and Snyder, S.H. Imaging Opiate Receptors in the Human Brain by Positron Tomography.  Comput. Assist. Tomogr. 9: 231‑236, 1985.
  8. De Souza, E.B., Anholt, R.H., Murphy, K.M., Snyder, S.H., and Kuhar, M.J. Peripheral‑Type Benzo­diazepine Receptors in Endocrine Organs: Autoradiographic Localization in Rat Pituitary, Adrenal, and Testis.  Endocrinology 116: 567‑573, 1985.
  9. Summers, R.J., Stephenson, J.A., and Kuhar, M.J. Localization of Beta‑Adrenoceptor Subtypes in Rat Kidney by Light Microscopic Autoradiography.  Pharmacol. Exp. Ther. 232: 561‑569, 1985.
  10. Uhl, G.R., Whitehouse, P.J., Price, D.L., Tourtelotte, W.W., and Kuhar, M.J. Parkinson’s Disease: Depletion of Substantia Nigra Neurotensin Receptors.  Brain Res. 308: 186‑190, 1984.
  11. Wagner, H.N., Jr., Dannals, R.F., Frost, J.J., Wong, D.F., Ravert, H.T., Wilson, A.A., Links, J.M., Burns, H.D., Kuhar M.J., and Snyder, S.H. Imaging Neuroreceptors in the Living Human Brain. Korean J. Nucl. Med. 18: 95‑101, 1984.
  12. Burns, H.D., Dannals, R.F., Langstrom, B., Ravert, H.T., Zemyan, S.E., Duelfer, T., Wong, D.F., Frost, J.J., Kuhar, M.J., and Wagner, H.N., Jr. (3‑N‑[11C]methyl)Spiperone, a Ligand Binding to Dopamine Receptors: Radiochemical Synthesis and Biodistribution Studies in Mice.  Nucl. Med. 25(11): 1222‑1227, 1984.
  13. Lepor, H. and Kuhar, M.J. Characterization of Muscarinic Cholinergic Receptor Binding in the Vas Deferens, Bladder, Prostate and Penis of the Rabbit.  Urol. 132: 392‑396, 1984.
  14. Lepor, H. and Kuhar, M.J. Characterization and Localization of the Muscarinic Cholinergic Receptor in Human Prostatic Tissue.  Urol. 132: 397‑402, 1984.
  15. Wong, D.F., Wagner, H.N., Jr., Dannals, R.F., Links, J.M., Frost, J.J., Ravert, H.T., Wilson, A.A., Rosenbaum, A.E., Gjedde, A., Douglass, K.H., Petronis, J.D., Folstein, M.F., Thomas Toung, J.K., Burns H.D., and Kuhar, M.J. Effects of Age on Dopamine and Serotonin Receptors Measured by Positron Tomography in the Living Human Brain.  Science 226: 1393‑1396, 1984.
  16. Kuhar, M.J. and Unnerstall, J.R. Mapping Receptors for Alpha‑2 Agonists in the Central Nervous System. J. Cardiovasc. Pharmacol. 61(Suppl. 3):  S536‑S542, 1984.
  17. Peroutka, S.J. and Kuhar, M.J. Autoradiographic Localization of 5‑HT1 Receptors to Human and Canine Basilar Arteries.  Brain Res. 310: 193‑197, 1984.
  18. De Souza, E.B. and Kuhar, M.J. Dopamine Receptors in the Anterior Lobe of the Human Pituitary Gland: Autoradiographic Localization.  Brain Res. 306: 391‑395, 1984.
  19. De Souza, E.B., Perrin, M.H., Insel, T.R., Vale W., and Kuhar, M.J. Corticotropin‑Releasing Factor Receptors in Rat Forebrain: Autoradiographic Identification.  Science 224: 1449‑1451, 1984.
  20. Whitehouse, P.J., Lynch, D., and Kuhar, M.J. Effects of Postmortem Delay and Temperature on Neurotransmitter Receptor Binding in a Rat Model of the Human Autopsy Process.  Neurochem. 43: 553‑559, 1984.
  21. Uhl, G.R. and Kuhar, M.J. Chronic Neuroleptic Treatment Enhances Neurotensin Receptor Binding in Human and Rat Substantia Nigra.  Nature 309: 350‑352, 1984.
  22. Wamsley, J.K., Zarbin, M.A., and Kuhar, M.J. Distribution of Muscarinic Cholinergic High and Low Affinity Agonist Binding Sites: A Light Microscopic Autoradiographic Study.  Brain Res. Bull. 12: 233‑243, 1984.
  23. Unnerstall, J.R., Kopajtic, T.A., and Kuhar, M.J. Distribution of Alpha‑2 Agonist Binding Sites in the Rat and Human Central Nervous System: Analysis of Some Functional, Anatomical Correlates of the Pharmacologic Effects of Clonidine and Related Adrenergic Agents.  Brain Res. Rev. 7: 69‑101, 1984.
  24. De Souza, E.B., Perrin, M.H., Rivier, J., Vale, W.W., and Kuhar, M.J. Corticotropin‑Releasing Factor Receptors in Rat Pituitary Gland: Autoradiographic Localization. Brain Res. 296: 202‑207, 1984.
  25. Wagner, H.N., Jr., Burns, H.D., Dannals, R.F., Wong, D.F., Langstrom, B., Duelfer, T., Frost, J.J., Ravert, H.T., Links, J.M., Rosenbloom, S.B., Lukas, S.E., Kramer A.V., and Kuhar, M.J. Assess­ment of Dopamine Receptor Densities in the Human Brain with Carbon‑11 Labeled N‑Methylspiperone.  Neurol. 15(Suppl.): S79‑S84, 1984.
  26. Smith, G.T., Moran, T.H., Coyle, J.T., Kuhar, M.J., O’Donohue, T.L., and McHugh, P.R. Anatomic Localization of Cholecystokinin Receptors to the Pyloric Sphincter.  J. Physiol. 246: R127‑R130, 1984.
  27. Summers, R.J. and Kuhar, M.J. Autoradiographic Localization of Alpha‑adrenoceptors in Rat Kidney.  J. Pharmacol. 91: 305‑310, 1983.
  28. Lo, M.M.S., Niehoff, D.L., Kuhar, M.J., and Snyder, S.H. Differential Localization of Type I and II Benzodiazepine Binding Sites in Substantia Nigra.  Nature 306: 57‑60, 1983.
  29. Freed, W.J., Ko, G.N., Niehoff, D.L., Kuhar, M.J., Hoffer, B.J., Olson, L., Cannon‑Spoor, H.E., Morishisa, J.M., and Wyatt, R.J. Normalization of Spiroperidol Binding in the Denervated Rat Striatum by Homologous Grafts of Substantia Nigra.  Science 222: 937‑939, 1983.
  30. Niehoff, D.L. and Kuhar, M.J. Benzodiazepine Receptors:  Localization in Rat Amygdala.  Neurosci. 3: 2091‑2097, 1983.
  31. Niehoff, D.L., Mashal, R.D., and Kuhar, M.J. Benzodiazepine Receptors:  Preferential Stimulation of Type 1 Receptors by Pentobarbital.  J. Pharmacol. 92: 131‑134, 1983.
  32. Lo, M.M.S., Niehoff, D.L., Kuhar, M.J., and Snyder, S.H. Autoradiographic Differentiation of Multiple Benzodiazepine Receptors by Detergent Solubilization and Pharmacologic Specificity.  Lett. 39: 37‑44, 1983.
  33. Zarbin, M.A., Palacios, J.M., Wamsley J.K., and Kuhar, M.J. Axonal Transport of Beta‑Adrenergic Receptors: Antero‑ and Retrogradely Transported Receptors Differ in Agonist Affinity and Nucleotide Sensitivity.  Pharmacol. 24: 341‑348, 1983.
  34. Wagner, Jr., H.N., Burns, H.D., Dannals, R.F., Wong, D.F., Langstrom, B., Duelfer, T., Frost, J.J., Ravert, H.T., Links, J.M., Rosenbloom, S.B., Lukas, S.E., Kramer A.V., and Kuhar, M.J. Imaging Dopamine Receptors in the Human Brain by Positron Tomography.  Science 221(4617): 1264‑1266, 1983.
  35. Whitehouse, P.J., Wamsley, J.K., Zarbin, M.A., Price, D.L., Tourtellotte, W.W., and Kuhar, M.J. Amyotrophic Lateral Sclerosis: Alterations in Neurotransmitter Receptors.  Neurol. 14: 8‑16, 1983.
  36. Wolf, S.S., Moody, T.W., O’Donohue, T.L., Zarbin M.A., and Kuhar, M.J. Autoradiographic Visuali­zation of Rat Brain Binding Sites for Bombesin‑like Peptides.  J. Pharmacol. 87: 163‑164, 1983.
  37. Zarbin, M.A., Innis, R.B., Wamsley, J.K., Snyder, S.H., and Kuhar, M.J. Autoradiographic Locali­zation of Cholecystokinin Receptors in Rodent Brain.   Neurosci. 3: 877‑906, 1983.
  38. Goodman, R.R., Kuhar, M.J., Hester, L., and Snyder, S.H. Adenosine Receptors: Autoradiographic Evidence for their Location on Axon Terminals of Excitatory Neurons.  Science 220: 967‑969, 1983.
  39. Unnerstall, J.R., Molliver, M.E., Kuhar, M.J., and Palacios, J.M. Ontogeny of Opiate Binding Sites in the Hippocampus, Olfactory Bulb and Other Regons of the Rat Forebrain by Autoradiographic Methods.  Brain Res. 7: 157‑169, 1983.
  40. Atweh, S.F. and Kuhar, M.J. Distribution and Physiological Significance of Opioid Receptors in the Brain.  Med. Bull. 39: 47‑52, 1983.
  41. Palacios, J.M. and Kuhar, M.J. Beta Adrenergic Receptor Localization in Rat Brain by Light Microscopic Autoradiography.  Int. 4: 473‑490, 1982.
  42. Unnerstall, J.R., Niehoff, D.L., Kuhar, M.J., and Palacios, J.M. Quantitative Receptor Autoradiog­raphy Using [3H]‑Ultrofilm: Application to Multiple Benzodiazepine Receptors.  Neurosci. Meth. 6: 59‑73, 1982.
  43. Zarbin, M.A., Wamsley, J.K., and Kuhar, M.J. Axonal Transport of Muscarinic Cholinergic Receptors in Rat Vagus Nerve: High and Low Affinity Agonist Receptors Move in Opposite Directions and Differ in Nucleotide Sensitivity.  Neurosci. 2: 934‑941, 1982.
  44. Palacios, J.M., Kuhar, M.J., Rapoport, S.I., and London, E.D. Effects of Gamma‑aminobutyric Acid and Antagonist Drugs on Local Cerebral Glucose Utilization.  Neurosci. 2: 853‑860, 1982.
  45. Kuhar, M.J. and Unnerstall, J.R. In vitro Receptor Autoradiography: Loss of Label during Ethanol Dehydration and Preparative Procedures.  Brain Res. 244: 178‑181, 1982.
  46. Niehoff, D.L., Mashal, R.D., Horst, W.D., O’Brien, R.A., Palacios, J.M., and Kuhar, M.J. Binding  of a Radiolabeled Triazoloprydazine to a Subtype of Benzodiazepine Receptor in the Rat Cerebellum.  Pharmacol. Exp. Ther. 221: 670‑675, 1982.
  47. Kuhar, M.J. Receptors for Clonidine in Brain: Insights into Therapeutic Actions.  Clin. Psychiat. 43, 17‑19, 1982.
  48. Wamsley, J.K., Zarbin, M.A., Young, W.S., III, and Kuhar, M.J. Distribution of Opiate Receptors in the Monkey Brain:  An Autoradiographic Study.  Neuroscience 7: 595‑613, 1982.
  49. Palacios, J.M. and Kuhar, M.J. Ontogeny of High‑Affinity GABA and Benzodiazepine Receptors in the Rat Cerebellum: An Autoradiographic Study.  Brain Res. 2: 531‑539, 1982.
  50. Palacios, J.M. and Kuhar, M.J. Neurotensin Receptors are Located on Dopamine‑Containing Neurons in Rat Midbrain.  Nature 294: 587‑589, 1981.
  51. Unnerstall, J.R., Kuhar, M.J., Niehoff, D.L., and Palacios, J.M. Benzodiazepine Receptors are Coupled to a Subpopulation of Gamma-Aminobutyric Acid (GABA) Receptors: Evidence from a Quantitative Autoradiographic Study.  Pharmacol. Exp. Ther. 218: 797-804, 1981.
  52. Wamsley, J.K., Palacios, J.M., and Kuhar, M.J. Autoradiographic Localization of Opioid Receptors in the Mammalian Retina.  Lett. 27: 19-24, 1981.
  53. Palacios, J.M., Wamsley, J.K., and Kuhar, M.J. High Affinity GABA‑Receptors:  Autoradiographic Localization.  Brain Res. 222: 285‑308, 1981.
  54. Palacios, J.M., Niehoff, D.L., and Kuhar, M.J. Receptor Autoradiography with Tritium‑Sensitive Film:  Potential for Computerized Densitometry.  Lett. 25: 101‑105, 1981.
  55. Zarbin, M.A., Wamsley, J.K., Innis R.B., and Kuhar, M.J. Cholecystokinin Receptors:  Presence and Axonal Flow in the Rat Vagus Nerve.  Life Sci. 29: 697‑705, 1981.
  56. Wamsley, J.K., Zarbin, M.A., and Kuhar, M.J. Muscarinic Cholinergic Receptors Flow in the Sciatic Nerve.  Brain Res. 217: 155‑161, 1981.
  57. Kuhar, M.J., Taylor, N., Wamsley, J.K., Hulme, E.C., and Birdsall, N.J.M. Muscarinic Cholinergic Receptor Localization in Brain by Electron Microscopic Autoradiography.  Brain Res. 216: 1‑10, 1981.
  58. Zarbin, M.A., Innis, R.B., Wamsley, J.K., Snyder, S.H., and Kuhar, M.J. Autoradiographic Localization of CCK Receptors in Guinea Pig Brain.  J. Pharmacol. 71: 349‑350, 1981.
  59. Palacios, J.M., Kuhar, M.J., Rapoport S.I., and London, E.D. Increases and Decreases in Local Cerebral Glucose Utilization in Response to GABA Agonists.  J. Pharmacol. 71: 333‑336, 1981.
  60. Palacios, J.M., Wamsley, J.K., and Kuhar, M.J. GABA, Benzodiazepine and Histamine‑H1 Receptors in the Guinea Pig Cerebellum:  Effects of Kainic Acid Injections Studied by Autoradiographic Methods.  Brain Res. 214: 155‑162, 1981.
  61. Zarbin, M.A., Wamsley, J.K., and Kuhar, M.J. Glycine Receptor: Light Microscopic Autoradiographic Localization with [3H]‑Strychnine.  Neurosci. 1: 532‑547, 1981.
  62. Palacios, J.M., Niehoff, D.L., and Kuhar, M.J. [3H]‑Spiperone Binding Sites in Brain:  Autoradiographic Localization of Multiple Receptors.  Brain Res. 213: 277‑289, 1981.
  63. Palacios, J.M., Wamsley, J.K., and Kuhar, M.J. The Distribution of Histamine‑H1 Receptors in the Rat Brain: An Autoradiographic Study.  Neuroscience 6: 15‑38, 1981.
  64. Young, W.S., III, Niehoff, D.L., Kuhar, M.J., Beer B., and Lippa, A.S. Multiple Benzodiazepine Recep­­tor Localization by Light Microscopic Radiohistochemistry. J. Pharmacol. Exp. Ther. 216: 425‑430, 1981.
  65. Wamsley, J.K., Lewis, M.S., Young, W.S., III, and Kuhar, M.J. Autoradiographic Localization of Muscarinic Cholinergic Receptors in Rat Brainstem.  Neurosci. 1: 176-1912, 1981.
  66. Young, W.S., III, and Kuhar, M.J. Neurotensin Receptor Localization by Light Microscopic Auto­radiography in Rat Brain.  Brain Res. 206: 273‑285, 1981.
  67. Wamsley, J.K., Palacios, J.M., Young, W.S., III, and Kuhar, M.J. Autoradiographic Determination of Neurotransmitter Receptor Distributions in the Cerebral and Cerebellar Cortices.  Histochem. Cytochem. 29: 125‑135, 1981.
  68. Young, W.S., III, and Kuhar, M.J. Alpha‑2 Adrenergic Receptors are Associated with Renal Proximal Tubules.  J. Pharmacol. 67: 493‑495, 1980.
  69. Goodman, R.R., Snyder, S.H., Kuhar, M.J., and Young, W.S., III. Differentiation of Delta and Mu Opiate Receptor Localizations by Light Microscopic Autoradiography.  Natl. Acad. Sci. (USA) 77: 6239‑6243, 1980.
  70. Palacios, J.M. and Kuhar, M.J. Radiohistochemical Localization of GABA Receptors.  Brain Res. Bull. 5(Suppl. 2): 145‑148, 1980.
  71. Wamsley, J.K., Zarbin, M.A., Birdsall, N.J.M., and Kuhar, M.J. Muscarinic Cholinergic Receptors:  Autoradiographic Localization of High and Low Affinity Binding Sites.  Brain Res., 200: 1‑12, 1980.
  72. Batzold, F., DeHaven, R., Kuhar M.J., and Birdsall, N. Inhibition of High Affinity Choline Uptake:  Structure Activity Studies.  Pharmacol. 29: 2413‑2416, 1980.
  73. Murrin, L.C., Coyle, J.T., and Kuhar, M.J. Striatal Opiate Receptors:  Pre‑ and Postsynaptic Localization.  Life Sci. 27: 1175‑1183, 1980.
  74. Young, W.S., III, Wamsley, J.K., Zarbin M.A., and Kuhar, M.J. Opioid Receptors Undergo Axonal Flow.  Science 210: 76‑78, 1980.
  75. Young, W.S., III, Kuhar, M.J., Roth J., and Brownstein, M.J. Radiohistochemical Localization of  Insulin Receptors in the Adult and Developing Rat Brain.  Neuropeptide 1: 15‑22, 1980.
  76. Kuhar, M.J., Birdsall, N.J.M., Burgen, A.S.V. and Hulme, E.C. Ontogeny of Muscarinic Receptors in Rat Brain.  Brain Res.  184: 375‑383, 1980.
  77. Palacios, J.M. and Kuhar, M.J. Beta‑adrenergic Receptor Localization by Light Microscopic Autoradiography.  Science 208: 1378‑1380, 1980.
  78. Wamsley, J.K., Young, W.S., III, and Kuhar, M.J. Immunohisto‑chemical Localization of Enkephalin Rat Forebrain.  Brain Res. 190: 153‑174, 1980.
  79. Young, W.S., III, and Kuhar, M.J. Serotonin Receptor Localization in Rat Brain by Light Microscopic Autoradiography.  J. Pharmacol. 62: 237‑239, 1980.
  80. Young, W.S., III, and Kuhar, M.J. Noradrenergic Alpha‑1 and Alpha‑2 Receptors:  Light Microscopic Autoradiographic Localization.  Natl. Acad. Sci. (USA) 77: 1696‑1700, 1980.
  81. Young, W.S., III, and Kuhar, M.J. Radiohistochemical Localization of Benzodiazepine Receptors in Rat Brain.  Pharmacol. Exp. Ther. 212: 337‑346, 1980.
  82. Palacios, J.M., Young, W.S., III, and Kuhar, M.J. Autoradiographic Localization of Gamma-aminobutyric (GABA) Receptors in Rat Cerebellum.  Natl. Acad. Sci. (USA) 77: 670‑674, 1980.
  83. Palacios, J.M. and Kuhar, M.J. Choline: Binding Studies Provide Some Evidence for a Weak, Direct Agonist Action in Brain.  Pharmacol. 16: 1084‑1088, 1979.
  84. Murrin, L.C., Gale, K., and Kuhar, M.J. Autoradiographic Localization of Neuroleptic and Dopamine Recep­tors in the Caudate‑Putamen and Substantia Nigra: Effects of Lesions.  J. Pharmacol. 60: 229‑235, 1979.
  85. Niehoff, D.L., Palacios, J.M., and Kuhar, M.J. In vivo Receptor Binding: Attempts to Improve Specific/ Non‑specific Ratios.  Life Sci. 25: 819‑826, 1979.
  86. Palacios, J.M., Niehoff, D.L., and Kuhar, M.J. Ontogeny of GABA and Benzodiazepine Receptors:  Effects of Triton X‑100, Bromide and Muscimol.  Brain Res. 179: 390‑395, 1979.
  87. Young, W.S., III, and Kuhar, M.J. A New Method for Receptor Autoradiography:  [3H]Opioid Receptors in Rat Brain.  Brain Res. 179: 255‑273, 1979.
  88. Young, W.S., III, and Kuhar, M.J. Noradrenergic Alpha‑1 and Alpha‑2 Receptors:  Autoradiographic Visualization.  J. Pharmacol. 59: 317‑319, 1979.
  89. Murrin, L.C. and Kuhar, M.J. Dopamine Receptors in the Rat Frontal Cortex:  An Autoradiographic Study.  Brain Res. 177: 279‑285, 1979.
  90. Young, W.S., III, and Kuhar, M.J. Neurotensin Receptors: Autoradiographic Localization in Rat CNS.  J. Pharmacol. 59: 161‑163, 1979.
  91. Palacios, J.M., Young, W.S., III, and Kuhar, M.J. Autoradiographic Localization of H1‑Histamine Receptors in Brain Using 3H‑Mepyramine: Preliminary Studies.  J. Pharmacol. 58: 295‑304, 1979.
  92. Young, W.S., III, and Kuhar, M.J. Autoradiographic Localization of Benzodiazepine Receptors in the Brain of Humans and Animals.  Nature 280: 393‑395, 1979.
  93. Klemm, N., Murrin, L.C., and Kuhar, M.J. Neuroleptic and Dopamine Receptors:  Autoradiographic Localization of 3H‑Spiperone in Rat Brain.  Brain Res. 169: 1‑9, 1979.
  94. Klemm, N. and Kuhar, M.J. Post‑mortem Changes in High Affinity Choline Uptake.  Neurochem. 32: 1487‑1494, 1979.
  95. Uhl, G.R., Goodman, R.R., Kuhar, M.J., Childers S.R., and Snyder, S.H. Immunohistochemical Mapping of Enkephalin‑Containing Cell Bodies, Fibers and Nerve Terminals in the Brain Stem of the Rat. Brain Res. 166: 75‑94, 1979.
  96. Kuhar, M.J., Mak, L.L., and Lietman, P.S. Autoradiographic Localization of 3H‑Gentamycin in the Proximal Renal Tubules of Mice.  Agents Chemother. 15: 131‑132, 1979.
  97. Uhl, G.R., Kuhar M.J., and Snyder, S.H. Enkephalin‑Containing Pathway:  Amygdaloid Efferents in the Stria Terminalis.  Brain Res. 149: 223‑228, 1978.
  98. Young, W.S., III, Uhl, G.R., and Kuhar, M.J. Iontophoresis of Neurotensin in the Area of the Locus Coeruleus.  Brain Res. 150: 431‑435, 1978.
  99. Kuhar, M.J. and Zarbin, M.A. Synaptosomal Transport:  A Chloride Dependence for Choline, GABA, Glycine and Several Other Compounds.  Neurochem. 31: 251‑256, 1978.
  100. Coyle, J.T., Molliver, M.E., and Kuhar, M.J. In situ Injection of Kainic Acid:  A Method for Selectively Lesioning Neuronal Cell Bodies While Sparing Axons of Passage.  Comp. Neurol. 180: 301‑324, 1978.
  101. Murrin, L.C., Lewis, M.S., and Kuhar, M.J. Amnio Acid Transport: Alterations Due to Synaptosomal Depolarization.  Life Sci. 22: 2009‑2016, 1978.
  102. Kuhar, M.J., Murrin, L.C., Malouf, A.T., and Klemm, N. Dopamine Receptor Binding in vivo: The Feasibility of Autoradiographic Studies.  Life Sci. 22: 203‑210, 1978.
  103. Kuhar, M.J., Atweh, S.F., Murrin, L.C., and Simon, J.R. Sodium‑Dependent High Affinity Choline Uptake: Its Significance and Practical Use.  Neuropsychopharmacologie 1(10): 469‑475, 1978.
  104. Atweh, S.F., Murrin, L.C., and Kuhar, M.J. Presynaptic Localization of Opiate Receptors in the Vagal and Accessory Optic System: An Autoradiographic Study.  17: 65‑71, 1978.
  105. Uhl, G.R., Kuhar, M.J., and Snyder, S.H. Neurotensin: Immunohisto‑ chemical Localization in Rat Central Nervous System.  Natl. Acad. Sci. (USA) 74: 4059‑4063, 1977.
  106. Murrin, L.C., DeHaven, R.N., and Kuhar, M.J. On the Relationship between 3H‑Choline Uptake Activation and 3H‑Acetylcholine Release.  Neurochem. 29: 681‑687, 1977.
  107. Murrin, L.C., Enna, S.J., and Kuhar, M.J. Autoradiographic Localization of 3H‑Reserpine Binding Sites in Rat Brain.  Pharmacol. Exp. Ther. 203: 564‑574, 1977.
  108. Atweh, S.F. and Kuhar, M.J. Autoradiographic Localization of Opiate Receptors in Rat Brain. III. The Telencephalon.  Brain Res. 134: 393‑405, 1977.
  109. Young, W.S., III, Bird, S.J., and Kuhar, M.J. Iontophoresis of Methionine Enkephalin in the Locus Coeruleus Area.  Brain Res. 129: 366‑370, 1977.
  110. Atweh, S.F. and Kuhar, M.J. Autoradiographic Localizatin of Opiate Receptors in Rat Brain. II. The Brain Stem.  Brain Res. 129: 1‑12, 1977.
  111. Simantov, R., Kuhar, M.J., Uhl, G.R., and Snyder, S.H. Opioid Peptide Enkephalin: Immuno­histo­chemical Mapping in Rat Central Nervous System.  Natl. Acad. Sci. (USA) 74: 2167‑2171, 1977.
  112. Atweh, S.F. and Kuhar, M.J. Autoradiographic Localization of Opiate Receptors in Rat. Brain.  Spinal Cord and Lower Medulla.  Brain Res. 124: 53‑67, 1977.
  113. Bird, S.J. and Kuhar, M.J. Iontophoretic Application of Opiates to the Locus Coeruleus.  Brain Res. 122: 523‑533, 1977.
  114. Murrin, L.C. and Kuhar, M.J. Activation of High Affinity Choline Uptake in vitro by Depolarizing Agents.  Pharmacol. 12: 1082‑1090, 1976.
  115. Pert, C.B., Kuhar, M.J., and Snyder, S.H. Opiate Receptor: Autoradiographic Localization in Rat Brain.  Natl. Acad. Sci. (USA) 73: 3729‑3733, 1976.
  116. Atweh, S.F. and Kuhar, M.J. Effects of Anesthetics and Septal Lesions and Stimulation of 3H‑Acetyl­choline Formation in Rat Hippocampus.  J. Pharmacol. 37: 311‑319, 1976.
  117. Simon, J.R. and Kuhar, M.J. High Affinity Choline Uptake: Ionic and Energy Requirements.  Neurochem. 27: 93‑99, 1976.
  118. Kuhar, M.J. and Yamamura, H.I. Localization of Cholinergic Muscarinic Receptors in Rat Brain by Light Microscopic Radioautography.  Brain Res. 110: 229‑243, 1976.
  119. Simon, J.R., Atweh, S., and Kuhar, M.J. Sodium‑Dependent High Affinity Choline Uptake: A Regulatory Step in the Synthesis of Acetylcholine.  Neurochem. 26: 909‑922, 1976.
  120. Simantov, R., Kuhar, M.J., Pasternak, G.W., and Snyder, S.H. The Regional Distribution of a Morphine-like Factor Enkephalin in Monkey Brain.  Brain Res. 106: 189‑197, 1976.
  121. Simon, M.R., Contrera, J.F., and Kuhar, M.J. Binding of [3H] Kainic Acid, an Analogue of L‑Glutamate, to Brain Membranes.  Neurochem. 26: 141‑147, 1975.
  122. Atweh, S., Simon, J.R., and Kuhar, M.J. Utlization of Sodium‑Dependent High Affinity Choline Uptake in vitro as a Measure of the Activity of Cholinergic Neurons in vivo.  Life Sci. 17: 1535‑1544, 1975.
  123. Rommelspacher H, Kuhar MJ. Proceedings: Effect of drugs on alterations of neuronal impulse flow of a central cholinergic tract. Naunyn Schmiedebergs Arch Pharmacol. 1975;287 Suppl:R10 PMID:167295
  124. Rommelspacher, H. and Kuhar, M.J. Effects of Drugs and Axotomy on Acetylcholine Levels in Central Cholinergic Neurons.  Naunyn‑Schmiedeberg’s Arch. Pharmacol. 291: 17‑21, 1975.
  125. Kuhar, M.J., Simon, J.R., and Taylor, N. Serotonergic Synaptosomes from Rat Hippocampus:  Lack of Acetylcholinesterase.  Brain Res. 99: 415‑418, 1975.
  126. Kuhar, M.J., DeHaven, R.N., Yamamura, H.I., Rommelspacher, H., and Simon, J.R. Further Evidence for Cholinergic Habenulo-Interpeduncular Neurons: Pharmacologic and Functional Characteristics.   Brain Res. 97: 265‑276, 1975.
  127. Bunney, B.S., Walters, J.R., Kuhar, M.J., Roth R.H., and Aghajanian, G.K. D & L Amphetamine Stereoisomers: Comparative Potencies in Affecting the Firing of Central Dopaminergic and Noradrenergic Neurons.  Comm. 1: 177‑190, 1975.
  128. Enna, S.J., Kuhar, M.J., and Snyder, S.H. Regional Distribution of Postsynaptic Receptor Binding for Gamma‑Aminobutyric Acid (GABA) in Monkey Brain.  Brain Res. 93: 168‑174, 1975.
  129. Pert, C.B., Kuhar, M.J., and Snyder, S.H. Autoradiographic Localization of the Opiate Receptor in Rat Brain.  Life Sci. 16: 1849‑1854, 1975.
  130. Simon, J.R. and Kuhar, M.J. Impulse‑Flow Regulation of High Affinity Choline Uptake in Brain Cholinergic Nerve Terminals.  Nature (London.) 255: 162‑163, 1975.
  131. Kuhar, M.J. and Yamamura, H.I. Light Autoradiographic Localization of Cholinergic Muscarinic Receptors in Rat Brain by Specific Binding of a Potent Antagonist.  Nature 253: 560‑561, 1975.
  132. Snyder, S.H., Chang, K.J., Yamamura H.I., and Kuhar, M.J. Biochemical Identification of the Mammalian Muscarinic Cholinergic Receptor.  Proc. 34: 1915‑1921, 1975.
  133. Simon, J.R., Mittag, T.W., and Kuhar, M.J. Inhibition of Synaptosomal Uptake of Choline by Various Choline Analogs.  Pharmacol. 24: 1139‑1142, 1975.
  134. Tamir, H. and Kuhar, M.J. Association of Serotonin‑Binding Protein with Projections of the Midbrain Raphe Nuclei.  Brain Res. 83: 169‑172, 1975.
  135. Rommelspacher, H. and Kuhar, M.J. Effects of Dopaminergic Drugs and Acute Medial Forebrain Bundle Lesions on Striatal Acetylcholine Levels.  Life Sci. 16: 65‑70, 1975.
  136. Yamamura, H.I., Kuhar, M.J., and Snyder, S.H. In vivo Identification of Muscarinic Cholinergic Receptor Binding in Rat Brain.  Brain Res. 80: 170‑176, 1974.
  137. Owellen, R.J., Donigian, D.W., Hartke, C.A., Dickerson, R.M., and Kuhar, M.J. The Binding of Vinblastine to Tubulin and to Participate Fractions of Mammalian Brain. Cancer Res. 34: 3180‑3186, 1974.
  138. Rommelspacher, H., Goldberg, A.M., and Kuhar, M.J. Action of Hemicholinium‑3 on Cholinergic Nerve Terminals After Alteration of Neuronal Impulse Flow.  Neuropharmacology 13: 1015‑1023, 1974.
  139. Rommelspacher, H. and Kuhar, M.J. Effects of Electrical Stimulation on Acetylcholine Levels in Central Cholinergic Nerve Terminals.  Brain Res. 81: 243‑251, 1974.
  140. Dismukes, K., Kuhar, M.J., and Snyder, S.H. Brain Histamine Alterations After Hypothalamic Isolation.  Brain Res. 78: 144‑151, 1974.
  141. Synder, S.H., Brown, B., and Kuhar, M.J. The Subsynaptosomal Localization of Histamine, Histidine Decarboxylase and Histamine Methyltransferase in Rat Hypothalamus.  Neurochem. 23: 37‑45, 1974.
  142. Kuhar, M.J. and Rommelspacher, H. Acetylcholinesterase‑Staining Synaptosomes from Rat Hippo­campus: Relative Frequency and Tentative Estimation of Internal Concentration of Free or “Labile Bound” Acetylcholine.  Brain Res. 77: 85‑96, 1974.
  143. Mulder, A.H., Yamamura, H.K., Kuhar, M.J., and Snyder, S.H. Release of Acetylcholine from Hippo­campal Slices by Potassium Depolarization: Dependence on High Affinity Choline Uptake.  Brain Res. 70: 372‑376, 1974.
  144. Kuhar, M.J. and Simon, J.R. Acetylcholine Uptake: Lack of Association with Cholinergic Neurons.  Neurochem. 22: 1135‑1137, 1974.
  145. Yamamura, H.I., Kuhar, M.J., Greenberg, D., and Snyder, S.H. Muscarinic Cholinergic Receptor Binding: Regional Distribution in Monkey Brain.  Brain Res. 66: 541‑546, 1974.
  146. Coyle, J.T. and Kuhar, M.J. Subcellular Localization of Dopamine Beta‑Hydroxylase and Endogenous Norepinephrine in the Rat Hypothalamus.  Brain Res. 65: 475‑487, 1974.
  147. Sethy, V.H., Kuhar, M.J., Roth, R.H., Van Woert, M.H., and Aghajanian, G.K. Cholinergic Neurons:  Effect of Acute Septal Lesion on Acetylcholine and Choline Content of Rat Hippocampus.  Brain Res. 55: 481‑484, 1973.
  148. Sethy, V.H., Roth, R.H., Kuhar, M.J., and Van Woert, M.H. Choline and Acetylcholine:  Regional Distribution and Effect of Degeneration of Cholinergic Nerve Terminals in the Rat Hippocampus.  Neuropharmacology 12: 819‑823, 1973.
  149. Kuhar, M.J., Pert, C.B., and Snyder, S.H. Regional Distribution of Opiate Receptor Binding in Monkey and Human Brain.  Nature 245: 447‑450, 1973.
  150. Kuhar, M.J., Sethy, V.H., Roth, R.H., and Aghajanian, G.K. Choline: Selective Accumulation by Central Cholinergic Neurons. Neurochem. 20: 581‑593, 1973.
  151. Kuhar, M.J. and Aghajanian, G.K. Selective Accumulation of 3H‑Serotonin by Nerve Terminals of Raphe Neurones: An autoradiographic Study.  Nature 241: 187‑189, 1973.
  152. Aghajanian, G.K., Kuhar, M.J., and Roth, R.H. Serotonin‑Containing Neuronal Perikarya and Terminals: Differential Effects of p‑Clorophenylalanine.  Brain Res. 54: 85‑101, 1973.
  153. Bustos, G., Kuhar, M.J., and Roth, R.H. Effect of Gamma‑ Hydroxybutyrate on Dopamine Synthesis and Uptake by Rat Striatum.  Pharmacol. 21: 2649‑2652, 1972.
  154. Kuhar, M.J., Roth, R.H., and Aghajanian, G.K. Synthesis of Catecholamines in the Locus Coeruleus from 3H‑Tyrosine in vivo.  Pharmacol. 21: 2280‑2282, 1972.
  155. Kuhar, M.J., Aghajanian, G.K., and Roth, R.H. Tryptophan Hydroxylase Activity and Synaptosomol Uptake of Serotonin in Discrete Brain Regions after Midbrain Raphe Lesions:  Correlations with Serotonin Levels and Histochemical Fluorescence.  Brain Res. 44: 165‑176, 1972.
  156. Kuhar, M.J., Roth, R.H., and Aghajanian, G.K. Synaptosomes from Forebrains of Rats with Midbrain Raphe Lesions:  Selective Reduction of Serotonin Uptake.  Pharmacol. Exp. Ther. 181: 36‑45, 1972.
  157. Kuhar, M.J., Roth, R.H., and Aghajanian, G.K. Selective Reduction of Tryptophan Hydroxylase Activity in Rat Forebrain after Midbrain Raphe Lesions.  Brain Res. 35: 167‑176, 1971.
  158. Kuhar, M.J. A Possible Mechanism for the Pathogenic Action of Monosodium Glutamate.  Comm. Chem. Pathol. Pharmacol. 2: 95‑97, 1971.
  159. Wofsey, A.R., Kuhar, M.J., and Snyder, S.H. A Unique Synaptosomal Fraction, Which Accumulates Glutamic and Aspartic Acids in Brain Tissue.  Natl. Acad. Sci. (USA) 68: 1102‑1106, 1971.
  160. Gfeller, E., Kuhar, M.J., and Snyder, S.H. Neurotransmitter‑Specific Synaptosomes in Rat Corpus Striatum: Morphological Variations.  Natl. Acad. Sci. (USA) 68: 155‑159, 1971.
  161. Kuhar, M.J., Taylor, K.N., Snyder, S.H. The Subcellular Localization of Histamine and Histamine Methyl­transferase in Rat Brain.  Neurochem. 18: 1515‑1527, 1971.
  162. Kuhar, M.J., Shaskan, E.G., and Snyder, S.H. The Subcellular Distribution of Endogenous and Exogenuous Serotonin in Brain Tissue:  Comparison of Synaptosomes Storing Serotonin, Norepinephrine, and Gamma‑Aminobutyric Acid.  Neurochem. 18: 333‑343, 1971.
  163. 2.Kuhar, M.J., Green, A.I., Snyder, S.H., and Gfeller, E.  Separation of Synaptosomes Storings Catecholamines and Gamma‑Aminobutyric Acid in Rat Corpus Striatum.  Brain Res. 21: 405‑417, 1970.
  164. 1.Kuhar, M.J. and Snyder, S.H.  The Subcellular Distribution of Free 3H‑Glutamic Acid in Rat Cerebral Cortical Slices. J. Pharmacol. Exp. Ther. 171: 141‑152, 1970.
  165. De Souza, E.B., Whitehouse, P.J., Kuhar, M.J., Price, D.L., and Vale, W.W. Reciprocal Changes in Corticotropin‑Releasing Factor (CRF)‑Like Immunoreactivity and CRF Receptors in Cerebral Cortex of Alzheimer’s Disease.  Nature 319: 593‑595, 1986.
  166. De Souza, E.B., Goeders, N.E., and Kuhar, M.J. Benzodiazepine Receptors in Rat Brain are Altered by Adrenalectomy.  Brain Res. 381: 176‑181, 1986.
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  171. Wong, D.F., Wagner, H.N., Jr., Pearlson, G., Dannals, R.F., Links, J.M., Ravert, H.T., Wilson, A.A., Suneja, S., Bjorvvinssen, E., Kuhar, M.J., and Tune, L. Dopamine Receptor Binding of C‑11‑2‑N‑ Methylspiperone in the Caudate in Schizophrenia and Bipolar Disorder:  A Preliminary Report.  Bull. 21(3): 595‑598, 1985.
  172. Whitehouse, P.J., Trifiletti, R.R., Jones, B.E., Folstein, S., Price, D.L., Snyder, S.H., and Kuhar, M.J. Neurotransmitter Receptor Alterations in Huntington’s Disease: Autoradiographic and Homogenate Studies with Special Reference to Benzodiazepine Receptor Complexes.  Neurol. 18(2): 202‑210, 1985.
  173. Zarbin, M.A., Kuhar, M.J., O’Donohue, T.L., Wolf, S.S., and Moody, T.W. Autoradiographic Localization of (125I‑TYR4) Bombesin‑Binding Sites in Rat Brain.  Neurosci. 5: 429‑437, 1985.
  174. Millington, W.R., Aizenman, E., Bierkamper, G.G., Zarbin, M.A., and Kuhar, M.J. Axonal Transport of Alpha‑Bungarotoxin Binding Sites in Rat Sciatic Nerve.  Brain Res. 340: 269‑276, 1985.
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  176. Goeders, N.E. and Kuhar, M.J. Benzodiazepine Receptor Binding in vivo with [3H]‑Ro 15‑1788.  Life Sci. 37: 345‑355, 1985.
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  185. Porrino, L.J., Ritz, M.C., Goodman, N.L., Sharpe, L.G., Kuhar, M.J., and Goldberg, S.R. Differential Effects of the Pharmacological Manipulation of Serotonin Systems on Cocaine and Amphetamine Self-administration in Rats. Life Sci. 45: 1529‑1535, 1989.
  186. Grigoriadis, D.E., Wilson, A.A., Lew, R., Sharkey, J.S., and Kuhar, M.J. Dopamine Transport Sites Selectively Labeled by a Novel Photoaffinity Probe: 125I‑DEEP.  Neurosci. 9(8): 2664‑2670, 1989.
  187. Lew, R., Grigoriadis, D.E., Sharkey, J., and Kuhar, M.J. Dopamine Transporter:  Solubilization From Dog Caudate Nucleus.  Synapse 3: 372‑375, 1989.
  188. Ritz, M.C. and Kuhar, M.J. Relationship Between Self‑administration of Amphetamine and Monoamine Receptors in Brain: Comparison With Cocaine.  Pharmacol. Exp. Ther. 248: 1010‑1017, 1989.
  189. Sharkey, J., Ritz, M.C., Schenden, J.A., Hanson R.C., and Kuhar, M.J. Cocaine Inhibits Muscarinic Cholinergic Receptors in Heart and Brain.  Pharmacol. Exp. Ther. 246: 1048-1052, 1988.
  190. O’Hearn, E., Battaglia, G., De Souza, E.B., Kuhar, M.J., and Molliver, M.E. Methylenedioxy­amphetamine (MDA) and Methylenedioxymethamphetamine (MDMA) Cause Selective Ablation of Serotonergic Axon Terminals in Forebrain: Immunocytochemical Evidence for Neurotoxicity.  Neurosci. 8: 2788‑2803, 1988.
  191. Sharkey, J., Glen, K.A., Wolfe, S., and Kuhar, M.J. Cocaine Binding at Sigma Receptors.  J. Pharmacol. 149: 171‑174, 1988.
  192. Goeders, N.E., Ritz, M.C., and Kuhar, M.J. Buspirone Enhances Benzodiazepine Receptor Binding in vivo.  Neuropharmacology 27: 275‑280, 1988.
  193. De Souza, E.B., Schmidt, W.K., and Kuhar, M.J. Nalbuphine: An Autoradiographic Opioid Receptor Binding Profile in the Central Nervous System of an Agonist/Antagonist Analgesic.  Pharmacol. Exp. Ther. 244: 391‑402, 1988.
  194. Kuhar, M.J. Imaging Receptors for Drugs in Neural Tissue.  Neuropharmacology 26: 911‑916, 1987.
  195. Whitehouse, P.J., Vale, W.W., Zweig, R.M., Singer, H.S., Mayeux, R., Kuhar, M.J., Price, D.L., and De Souza, E.B. Reductions in Corticotropin‑Releasing Factor‑Like Immunoreactivity in Cerebral Cortex in Alzheimer’s Disease, Parkinson’s Disease, and Progressive Supranuclear Palsy.  Neurology 37: 9805‑909, 1987.
  196. Battaglia, G., Yeh, S.Y., O’Hearn, E., Molliver, M.E., Kuhar, M.J., and De Souza, E.B. 3,4‑Methylene­dioxymethamphetamine and 3,4‑Methylenedioxyamphetamine Destroy Serotonin Terminals in Rat Brain: Quantification of Neurodegeneration by Measurement of [3H]Paroxetine‑Labeled Serotonin Uptake Sites. Pharmacol. Exp. Ther. 242: 911‑916, 1987.
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  198. Frost, J.J., Smith, A.C. , Kuhar, M.J., Dannals R.F., and Wagner H.N., Jr. In vivo Binding of 3H‑N‑Methyl­spiperone to Dopamine and Serotonin Receptors.  Life Sci. 40: 987‑995, 1987.
  199. Jampel, H.D., Lynch, M.G., Brown, R.H., Kuhar M.J., and De Souza, E.B. ß‑Adrenergic Receptors in Human Trabecular Meshwork.  Ophthalmol. Vis. Sci. 28: 772‑779, 1987.
  200. Goeders, N.E. and Kuhar, M.J. Chronic Cocaine Administration Induces Opposite Changes in Dopamine Receptors in the Striatum and Nucleus Accumbens.  Alcohol Drug Res. 7: 207‑216, 1987.
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  207. Kuhar, M.J., Boja, J.W., and Cone, E.J. Phencyclidine Binding to Striatal Cocaine Receptors.  Neuropharmacology 29: 295‑297, 1990.
  208. Boja, J.W., Carroll, F.I., Abdur Rahman, M., Philip, A., Lewin, A.H., and Kuhar, M.J. New, Potent Cocaine Analogs: Ligand Binding and Transport Studies in Rat Striatum.  J. Pharmacol. 184: 329‑332, 1990.
  209. Zarbin, M.A., Wamsley, J.K., and Kuhar, M.J. Anterograde Transport of Opioid Receptors in Rat Vagus Nerves and Dorsal Roots of Spinal Nerves: Pharmacology and Sensitivity to Sodium and Guanine Nucleotides.  Brain Res. 81: 267‑278, 1990.
  210. Naseree, T.M., Abraham, P., Kepler, J.A., Carroll, F.I., Lewin., A.H., and Kuhar, M.J. Synthesis of [3H]WIN 35,065‑2; A New Radioligand for Cocaine Receptors.  Labelled Compd. Radiopharmaceut. 28(9): 1011‑1016, 1990.
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  212. Lew, R., Grigoriadis, D., Wilson, A.A., Boja, J.W., Simantov, R., and Kuhar, M.J. Dopamine transporter: Deglycosylation with Exo‑ and Endo-glycosidases.  Brain Res. 539: 239‑246, 1991.
  213. Boja, J.W., Rahman, M.A., Abraham, P., Lewin, A.H., Carroll, F.I., and Kuhar, M.J. Isothiocyanate Derivatives of Cocaine: Irreversible Inhibition of Ligand Binding at the Dopamine Transporter.  Pharmacol. 39: 339‑345, 1991.
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  218. Battaglia, G., Sharkey, J., Kuhar, M.J., and De Souza, E.B. Neuroanatomic Specificity and Time  Course of Alterations in Rat Brain Serotonergic Pathways Induced by MDMA (3,4‑Methylenedioxy­methamphetamine): Assessment Using Quantitative Autoradiography.  Synapse 8: 249‑260, 1991.
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  220. Shimada, S., Kitiyama, S., Lin, C.-L., Patel, A., Nanthakumar, E., Gregor, P., Kuhar, M.J., and Uhl, G. Cloning and Expression of a Cocaine‑Sensitive Dopamine Transporter Complementary DNA. Science, 254: 576‑578, 1991.
  221. Kuhar, M.J., Lloyd, D.G., and Loats, H.L. Imaging Receptors by Autoradiography: Computer‑Assisted Approaches.  Chem. Neuroanat. 4: 319‑327, 1991.
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  223. Carroll, F.I., Rahman, M.A., Abraham, P., Parham, K., Lewin, A.H., Dannals, R.F., Shaya, E., Scheffel, U., Wong, D.F., Boja, J.W., and Kuhar, M.J. [123I]3b‑(4‑Iodophenyl)Tropan‑2b‑Carboxylic Acid Methyl Ester (RTI‑55), A Unique Cocaine Receptor Ligand for Imaging the Dopamine and Serotonin Transporters in vivo.  Chem. Res. 1: 289-294, 1991.
  224. Pögün, S., Scheffel, U., and Kuhar, M.J. Cocaine Displaces [3H]WIN35,428 Binding to Dopamine Up­take Sites in vivo More Rapidly than Mazindol or GBR 12909.  J. Pharmacol. 198: 203-205, 1991.
  225. Lewin, A.H., Gao, Y., Abraham, P., Boja, J.W., Kuhar M.J., and Carroll, F.I. 2b-Substituted Analogues of Cocaine.  Synthesis and Inhibition of Binding to the Cocaine Receptor.  Med. Chem. 35: 135-140, 1992.
  226. Abraham, P., Pitner, J.B., Lewin, A.H., Boja, J.W., Kuhar, M.J., and Carroll, F.I . N-Modified Analogues of Cocaine: Synthesis and Inhibition of Binding to the Cocaine Receptor. Med. Chem. 35: 141-144, 1992.
  227. Carroll, F.I., Lewin, A.H., Boja, J.W., and Kuhar, M.J. Cocaine Receptor: Biochemical Characteriza­tion and Structure-Activity Relationships of Cocaine Analogues at the Dopamine Transporter. Med.  Chem. 35: 969-981, 1992.
  228. Shaya, E.K., Scheffel, U., Dannals, R.F., Racaurte, G.A., Carroll, F.I., Wagner, H.N., Jr., Kuhar, M.J., and Wong, D.F. In vivo Imaging of Dopamine Reuptake Sites in the Primate Brain Using Single Photon Emission Computed Tomography (SPECT) and Iodine-123 Labeled RTI-55.  Synapse 10: 169-172, 1992.
  229. Cline, E.J., Scheffel, U., Boja, J.W., Carroll, F.I., Katz, J.L., and Kuhar, M.J. Behavioral Effects of Novel Cocaine Analogs:  A Comparison with in vivo Receptor Binding Potency.  Pharmacol. Exp. Ther. 260: 1174-1179, 1992.
  230. Patel, A., Boja, J.W., Lever, J., Lew, R., Simantov, R., Carroll, F.I., Lewin, A.H., Philip, A., Gao, Y., and Kuhar, M.J. A Cocaine Analog and a GBR Analog Label the Same Protein in Rat Striatal Membranes.  Brain Res. 576: 173-174, 1992.
  231. Carroll, F.I., Kuzemko, M.A., Gao, Y., Abraham, P., Lewin, A.H., Boja, J.W., and Kuhar, M.J. Synthesis and Ligand Binding of 3b-(3-Substituted Phenyl)- and 3b-(3,4-Disubstituted Phenyl)Tropane-2b-Carboxylic Acid Methyl Esters.  Chem. Res. 1: 382-387, 1992.
  232. Boja, J.W., Markham, L., Patel, A., Uhl G., and Kuhar, M.J. Expression of a Single Dopamine Trans­porter cDNA Can Confer Two Cocaine Binding Sites.  NeuroReport 3: 247-248, 1992.
  233. Cline, E.J., Terry, P., Carroll, F.I., Kuhar, M.J., and Katz, J.L. Stimulus Generalization from Cocaine to Analogs with High in vitro Affinity for Dopamine Uptake Sites. Behav. Pharmacol. 3: 113-116, 1992.
  234. Scheffel, U., Dannals, R.F., Cline, E.J., Ricaurte, G.A., Carroll, F.I., Abraham, P., Lewin, A.H., and Kuhar, M.J. [123/125I]RTI-55, an in vivo Label for the Serotonin Transporter.  Synapse 11: 134-139, 1992.
  235. Carroll, F.I., Gao, Y., Abraham, P., Lewin, A.H., Lew, R., Patel, A., Boja, J.W., and Kuhar, M.J. Probes for the Cocaine Receptor.  Potentially Irreversible Ligands for the Dopamine Transporter.  Med. Chem. 35: 1813-1817, 1992.
  236. Carroll, F.I., Abraham, P., Lewin, A.H., Parham, K.A., Boja, J.W., and Kuhar, M.J. Isopropyl and Phenyl Esters of 3b-(4-Substituted phenyl)tropan-2b-carboxylic Acids.  Potent and Selective Compounds for the Dopamine Transporter.  Med. Chem. 35: 2497-2500, 1992.
  237. Lew, R., Patel, A., Vaughan, R., Wilson, A., and Kuhar, M.J. Microheterogeneity of Dopamine Transporters in Rat Striatum and Nucleus Accumbens.  Brain Res. 584: 266-271, 1992.
  238. Cline, E.J., Scheffel, U., Boja, J.W., Mitchell, W.M., Carroll, F.I., Abraham, P., Lewin, A.H., and Kuhar, M.J. In vivo Binding of [125I]RTI-55 to Dopamine Transporters: Pharmacology and Regional Distribution with Autoradiography.  Synapse 12: 37-46, 1992.
  239. Boja, J.W., Mitchell, W.M., Patel, A., Kopajtic, T.A., Carroll, F.I., Lewin, A.H., Abraham, P., and Kuhar, M.J. High-Affinity Binding of [125I]RTI-55 to Dopamine and Serotonin Transporters in Rat Brain.  Synapse 12: 27-36, 1992.
  240. Rostene, W., Boja, J.W., Scherman, D., Carroll, F.I., and Kuhar, M.J. Dopamine Transport: Pharmaco­logical Distinction between the Synaptic Membrane and the Vesicular Transporter in Rat Striatum.  J. Pharmacol. 218: 175-177, 1992.
  241. Boja, J.W., McNeill, R.M., Lewin, A.H., Abraham, P., Carroll, F.I., and Kuhar, M.J. Selective Dopamine Transporter Inhibition by Cocaine Analogs.  NeuroReport 3: 984-986, 1992.
  242. Scheffel, U., Dannals, R.F., Wong, D.F., Yokoi, F., Carroll, F.I., and Kuhar, M.J. Dopamine Transporter Imaging with Novel, Selective Cocaine Analogs.  NeuroReport 3: 969-972, 1992.
  243. Vaughan, R.A., Uhl, G., and Kuhar, M.J. Recognition of Dopamine Transporters by Antipeptide Antibodies.  Cell. Neurosci. 4: 209-215, 1993.
  244. Patel, A., Uhl, G.R., and Kuhar, M.J. Species Differences in Dopamine Transporters: Postmortem Changes and Glycosylation Differences.  Neurochem. 61: 496-500, 1993.
  245. Cerruti, C., Walther, D.M., Kuhar, M.J. and Uhl, G.R. Dopamine Transporter mRNA Expression is Intense in Rat Midbrain Neurons and Modest Outside Midbrain.  Brain Res. 18: 181-186, 1993.
  246. Wong, D.W., Yung, B., Dannals, R.F., Shaya, E.S., Ravert, H.T., Chen, C.A., Chan, B., Folio, T., Scheffel, U., Ricaurte, G., Neumeyer, J.L., Wagner, H.N. Jr., and Kuhar, M.J. In vivo Imaging of Baboon and Human Dopamine Transporters by Positron Emission Tomography Using [11C]WIN 35,428.  Synapse 15: 130-142, 1993.
  247. Brouard, A., Pelaprat, D., Boja, J.W., Carroll, F.I., Vial, M., Kuhar, M.J., and Rostene, W. Potent Cocaine Analogs Inhibit [3H]Dopamine Uptake in Rat Mesencephalic Cells in Primary Cultures: Pharma­cological Selectivity of Embryonic Cocaine Sites.  Brain Res. 75: 13-17, 1993.
  248. Carroll, F.I., Gray, J.L., Abraham, P., Kuzemko, M.A., Lewin, A.H., Boja, J.W., and Kuhar, M.J. 3-Aryl-2-(3′-substituted-1′,2′,4′-oxadiazol-5′-yl)tropane Analogues of Cocaine: Affinities at the Cocaine Binding Site at the Dopamine, Serotonin, and Norepinephrine Transporters.  Med. Chem. 36(20): 2886-2890, 1993.
  249. Carroll, F.I., Kotian, P., Gray, J.L., Abraham, P., Kuzemko, M.A., Lewin, A.H., Boja, J.W., and Kuhar, M.J. 3b-(4′-Chlorophenyl)Tropan-2b-Carboxamides and Cocaine Amide Analogues:  New High Affinity and Selective Compounds for the Dopamine Transporter.  Chem. Res. 3: 468-472, 1993.
  250. Cerruti, C., Pilotte, N.S., Uhl, G., and Kuhar, M.J. Reduction in Dopamine Transporter mRNA after Cessation of Repeated Cocaine Administration.  Brain Res. 22: 132-138, 1994.
  251. Pögün, S., Baumann, M.H., and Kuhar, M.J. Nitric Oxide Inhibits [3H]Dopamine Uptake.  Brain Res. 641: 83-91, 1994.
  252. Scheffel, U., Kim, S., Cline, E.J., and Kuhar, M.J. Occupancy of the Serotonin Transporter by Fluoxetine, Paroxetine, and Sertraline: In vivo Studies with [125I] RTI-55. Synapse 16: 263-268, 1994.
  253. Boja, J.W., Kuhar, M.J., Kopajtic, T., Yang, E., Abraham, P., Lewin, A.H., and Carroll, M.J. Secondary Amine Analogues of 3b-(4′-Substituted phenyl)tropan-2b-carboxylic Acid Esters and N-Norco­caine Exhibit Enhanced Affinity for Serotonin and Norepinephrine Transporters.  Med. Chem. 37(18):  1220-1223, 1994.
  254. Pilotte, N.S., Sharpe, L.G., and Kuhar, M.J. Withdrawal of Repeated Intravenous Infusions of Cocaine Persistently Reduces Binding to Dopamine Transporters in the Nucleus Accumbens of Lewis Rats.  Pharmacol. Exp. Ther. 260: 963-969, 1994.
  255. Pögün, S., Dawson, V., and Kuhar, M.J. Nitric Oxide Inhibits 3H-Glutamate Transport in Synapto­somes. Synapse 18: 21-26, 1994.
  256. Carroll, F.I., Mascarella, S.W., Kuzemko, M.A., Gao, Y., Abraham, P., Lewin, A., Boja, J.W., and Kuhar, M.J. Synthesis, Ligand Binding, and QSAR (CoMFA and Classical) Study of 3b-(3′-Substituted phenyl)-,3b-(4′-Substituted phenyl)-, and 3b-(3′,4′-Disubstituted phenyl)tropane-2b-carboxylic Acid Methyl Esters.  Med. Chem.  37(18): 2865-2873, 1994.
  257. Patel, A.P., Cerruti, C., Vaughan, R.A., and Kuhar, M.J. Developmentally Regulated Glycosylation of Dopamine Transporter.  Brain Res. 83: 53-58, 1994.
  258. Brown, D.J., Luthra, S.K., Brown, G.D., Carroll, F.I., Kuhar, M.J., Osman, S., Waters, S.L., and Brady, F. [11C]RTI-121 – A Potential Radioligad for PET Studies of the Dopamine Transporter.  Labelled Compd. Radiopharmaceut. 35: 483, 1994.
  259. Carroll, F.I., Kotian, P., Dehghani, A., Gray J.L., Kuzemko, M.A., Parham, K.A., Abraham, P., Lewin, A.H., Boja, J.W., and Kuhar, M.J. Cocaine and 3b-(4′-Substituted phenyl)tropane-2b-carboxylic Acid Ester and Amide Analogues.  New High-Affinity and Selective Compounds for the Dopamine Transporter. J. Med. Chem. 38(2): 379-388, 1995.
  260. Volkow, N.D., Gatley, S.J. Fowler, J.S., Chen, R., Logan, J., Dewey, S.L., Ding, Y.-S., Pappas, N., King, P., MacGregor, R.R., Kuhar, M.J., Carroll, F.I. and Wolf, A.P. Long-Lasting Inhibition of in vivo Cocaine Binding to Dopamine Transporters by 3b-(4-Iodophenyl)Tropane-2-Carboxylic Acid Methyl Ester: RTI-55 or b Synapse 19(3): 206-211, 1995.
  261. Freed, C., Revay, R., Vaughan, R.A., Kriek, E., Grant, S., Uhl, G.R., and Kuhar, M.J. Dopamine Transporter Immunoreactivity in Rat Brain.  Comp. Neurol., 359: 340-349, 1995.
  262. Kotian, P., Abraham, P., Lewin, A.H., Mascarella, S.W., Boja, J.W., Kuhar, M.J., and Carroll, F.I. Synthesis and Ligand Binding Study of 3b-(4′-Substituted phenyl)-2b-(heterocyclic)tropanes.  Med. Chem., 38(18): 3451-3453, 1995.
  263. Scheffel, U., Taylor, G.F., Kepler, J.A., Carroll, F.I., and Kuhar, M.J. In vivo Labeling of Neuronal Nicotinic Acetylcholine Receptors with Radiolabeled Isomers of Norchloroepibatidine.  Neuro­Report 6: 2483-2488, 1995.
  264. Stathis, M., Scheffel, U., Lever, S.Z., Boja, J.W., Carroll, F.I., and Kuhar, M.J. Rate of Binding of Various Inhibitors at the Dopamine Transporter in vivo.  Psychopharmacology, 119: 376-384, 1995.
  265. Revay, R., Vaughan, R., Grant, S., and Kuhar, M.J. Dopamine Transporter Immunohistochemistry in Median Eminence, Amygdala, and Other Areas of the Rat Brain.  Synapse 22: 93-99, 1996.
  266. Pilotte, N.S., Sharpe, L.G., Rountree, S.D., and Kuhar, M.J. Cocaine Withdrawal Reduces Dopamine Transporter Binding in the Shell of the Nucleus Accumbens.  Synapse 22: 87-92, 1996.
  267. Nirenberg, M.J., Vaughan, R.A., Uhl, G.R., Kuhar, M.J., and Pickel, V.M. The Dopamine Transporter is Localized to Dendritic and Axonal Plasma Membranes of Nigrostriatal Dopaminergic Neurons.  Neurosci. 16(2): 436-447, 1996.
  268. Gatley, S.J., Volkow, N.D., Chen, R., Fowler, J.S., Carroll, F.I., and Kuhar, M.J. Displacement of RTI-55 from the Dopamine Transporter by Cocaine.  J. Pharmacol. 296: 145-151, 1996.
  269. Lever, J.R., Scheffel, U., Stathis, M., Seltzman, H.H., Wyrick, C.D., Abraham, P., Parham, K., Thomas, B.F., Boja, J.W., Kuhar, M.J., and Carroll, F.I. Synthesis and in vivo Studies of a Selective Ligand for the Dopamine Transporter:  3b-(4-[125I]Iodophenyl) Tropan-2b-Carboxylic Acid Isopropyl Ester ([125I]RTI-121). Nuclear Med Biol. 23: 277-284,1996.
  270. Scheffel, U., Steinert, C., Kim, S.E., Ehlers, M.D., Boja, J.W., and Kuhar, M.J. Effect of Dopamin­ergic Drugs on the in vivo Binding of [3H]WIN 35,428 to Central Dopamine Transporters.  Synapse 23: 61-69, 1996.
  271. Vaughan, R.A., Brown, V.L., McCoy, M.T., and Kuhar, M.J. Species- and Brain Region-Specific Dopamine Transporters: Immunological and Glycosylation Characteristics. J. Neurochem. 66: 2146-2152, 1996.
  272. Hume, S.P., Luthra, S.K., Brown, D.J., Opacka-Juffry, J., Osman, S., Ashworth, S., Myers, R., Brady, F., Carroll, F.I., Kuhar, M.J., and Brooks, D.J. Evaluation of [11C]RTI-121 as a Selective Radioligand for PET Studies of the Dopamine Transporter.  Med. Biol. 23: 377-384, 1996.
  273. Kotian, P., Mascarella, S.W., Abraham, P., Lewin, A.H., Boja, J.W., Kuhar, M.J., and Carroll, F.I. Synthesis, Ligand Binding, and Quantitative Structure-Activity Relationship Study of 3b-(4¢-Substituted phenyl)-2b-heterocyclic Tropanes: Evidence for an Electrostatic Interaction at the 2b-Position.  Med. Chem. 39: 2753-2763, 1996.
  274. Fleckenstein, A.E., Kopajtic, R.A., Boja, J.W., Carroll, F.I. and Kuhar, M.J. Highly Potent Cocaine Analogs Cause Long-Lasting Increases in Locomotor Activity.  J. Pharmacol. 311: 109-114, 1996.
  275. Vaughan, R.A. and Kuhar, M.J. Dopamine Transporter Ligand Binding Domains.  Biol. Chem. 271: 21672-21680, 1996.
  276. Houlihan, W.J., Boja, J.W., Parrino, V.A., Kopajtic, T.A. and Kuhar, M.J. Halogenated Mazindol Analogs as Potential Inhibitors of the Cocaine Binding Site at the Dopamine Transporter. J. Med. Chem. 39: 4935-4941, 1996.
  277. Blough, B.E., Abraham, P., Lewin, A.H., Kuhar, M.J., Boja, J.W. and Carroll, F.I. Synthesis and Transporter Binding Properties of 3b-(4′-Alkyl-, 4′-alkenyl-, and 4′-alkynylphenyl)nortropane-2b-carboxylic Acid Methyl Esters: Serotonin Transporter Selective Analogs.  Med. Chem. 39: 4027-4035, 1996.
  278. Holmquist, C.R., Keverline-Frantz, K.I., Abraham, P., Boja, J.W., Kuhar, M.J. and Carroll, F.I.3a-(4′-Substituted phenyl)tropane-2b-carboxylic Acid Methyl Esters: Novel Ligands with High Affinity and Selectivity at the Dopamine Transporter. Med. Chem. 39: 4139-4141, 1996.
  279. Y.-S., Gatley, S.J., Fowler, J.S., Volkow, N.D., Aggarwal, D., Logan, J., Dewey, S.L., Liang, F., Carroll, F.I. and Kuhar, M.J. Mapping Nicotinic Acetylcholine Receptors with PET.  Synapse 24: 403-407, 1996.
  280. Wong, D.F., Harris, J.C., Naidu, S., Yokoi, F., Marenco, S., Dannals, R.F., Ravert, H.T., Yaster, M., Evans, A., Rousset, O., Bryan, R.N., Gjedde, A., Kuhar, M.J. and Breese, G.R. Dopamine Transporters are Markedly Reduced in Lesch-Nyhan Disease in vivo.  Natl. Acad. Sci. USA 93: 5539-5543, 1996.
  281. Fleckenstein, A.E., Pögün, S., Carroll, F.I., and Kuhar, M.J. Recovery of Dopamine Transporter Binding and Function after Intrastriatal Administration of the Irreversible Inhibitor RTI-76 {3b-(3r-Chlorophenyl)Tropan-2b-Carboxylic Acid r-Isothiocyanatophenylethyl Ester Hydrochloride}.  Pharmacol. Exp. Ther. 279: 200-206, 1996.
  282. Chang, A.-C., Burgess, J.P., Mascarella, S.W., Abraham, P., Kuhar, M.J., and Carroll, F.I. Synthesis and Transporter Binding Properties of 2,3-Diphenyltropane Stereoisomers.  Comparison to 3b-Phenyl­tropane-2b-Carboxylic Acid Esters.  Med. Chem. 40: 1247-1251, 1997.
  283. Zhan, Y., Saindane, A.M., Scheffel, U., Carroll, F.I., Holmquist, C.R., Kepler, J.A., Taylor, G.F., and Kuhar, M.J.  RTI-352: 3a Analogue of RTI-55 as an in vivo Dopamine Transporter Binding Ligand.  Synapse 25: 389-392, 1997.
  284. Scheffel, U., Lever, J.R., Abraham, P., Parham, K.R., Mathews, W.B., Kopajtic, T., Carroll, F.I., and Kuhar, M.J. N-Substituted Phenyltropanes as in vivo Binding Ligands for Rapid Imaging Studies of the Dopamine Transporter.  Synapse 25: 345-349, 1997.
  285. Huff, R.A., Vaughan, R.A., Kuhar, M.J., and Uhl, G.R. Phorbol Esters Increase Dopamine Transporter Phosphorylation and Decrease Transport Vmax.  Neurochem. 68: 225-232, 1997.
  286. Vaughan, R.A., Huff, R.A., Uhl, G.R., and Kuhar, M.J. Protein Kinase C-mediated Phosphorylation and Func­tional Regulation of Dopamine Transporters in Striatal Synaptosomes.  Biol. Chem. 272: 15541-15546, 1997.
  287. Thiruvazhi, M., Abraham, P., Kuhar, M.J., and Carroll, F.I. Synthesis of the Isomers of (1R)-3-(Pheny­lthio)Tropane-2-Carboxylic Acid Methyl Ester. A New Class of Ligands for the Dopamine Transporter.  Commun: 555-556, 1997.
  288. Nirenberg, M.J., Chan, J., Vaughan, R.A., Uhl, G.R., Kuhar, M.J., and Pickel, V.M. Immunogold Localization of the Dopamine Transporter: An Ultrastructural Study of the Rat Ventral Tegmental Area.  Neurosci. 17(14): 5255-5262, 1997.
  289. Liang, F., Navarro, H.A., Abraham, P., Kotian, P., Ding, Y.-S., Fowler, J., Volkow, N., Kuhar, M.J., and Carroll, F.I. Synthesis and Nicotinic Acetylcholine Receptor Binding Properties of exo-2-(2′-fluoro-5′-pyridinyl)-7-azabicyclo-[2.2.1]heptane: A New Positron Emission Tomgraphy Ligand for Nicotinic Receptors.  Med. Chem. 40(15): 2293-2295, 1997.
  290. Smith, Y., Koylu, E.O., Couceyro, P., and Kuhar, M.J. Ultrastructural Localization of CART (Cocaine- and Amphetamine-Regulated Transcript) Peptides in the Nucleus Accumbens of Monkeys.  Synapse 27: 90-94, 1997.
  291. Couceyro, P.R., Koylu, E.O., and Kuhar, M.J. Further Studies on the Anatomical Distribution of CART by in situ  J. Chem. Neuroanat. 12: 229-241, 1997.
  292. Ding, Y.-S., Liang, F., Fowler, J.S., Kuhar, M.J., and Carroll, F.I. Synthesis of [18F]Norchlorofluoro­epibatidine and its N-methyl Derivative: New PET Ligands for Mapping Nicotinic Acetylcholine Receptors.  Labelled Compd. Radiopharmaceut. 39(10): 827-832, 1997.
  293. Couceyro, P., Shoaib, M., McCoy, M., Goldberg, S.R., and Kuhar, M.J. Cocaine Self-administration Alters Brain NADH Dehydrogenase mRNA Levels.  NeuroReport 8: 2437-2441, 1997.
  294. Nirenberg, M.J., Chan, J., Pohorille, A., Vaughan, R.A., Uhl, G.R., Kuhar, M.J. and Pickel, V.M. The Dopamine Transporter: Comparative Ultrastructure of Dopaminergic Axons in Limbic and Motor Compart­ments of the Nucleus Accumbens.  Neurosci. 17: 6899-6907, 1997.
  295. Koylu, E.O., Couceyro, P.R., Lambert, P.D., Ling, N.C., DeSouza, E.B., and Kuhar, M.J. Immuno­histochemical Localization of Novel CART Peptides in Rat Hypothalamus, Pituitary and Adrenal Gland.  Neuroendocrinol. 9: 823-833, 1997.
  296. Molina, P.E., Ding, Y.-S., Carroll, F.I., Liang, F., Volkow, N.D., Pappas, N., Kuhar, M., Abumrad, N., Gatley, S.J., and Fowler, J.S. Fluoro-norchloroepibatidine: Preclinical Assessment of Acute Toxicity. Nucl. Med. Biol. 24: 743-747, 1997.
  297. Wong DF, Pearlson GD, Tune LE, Young LT, Meltzer CC, Dannals RF, Ravert HT, Reith J, Kuhar MJ, Gjedde. A Quantification of neuroreceptors in the living human brain: IV. Effect of aging and elevations of D2-like receptors in schizophrenia and bipolar illness.  J Cereb Blood Flow Metab. 1997 Mar;17(3):331-42. PMID:9119906
  298. Blough, B.E., Abraham, P., Mills, A.C., Lewin, A.H., Boja, J.W., Scheffel, U.., Kuhar, M.J., and Carroll, F.I. 3b-(4-Ethyl-3-iodophenyl)nortropane-2b-carboxylic Acid Methyl Ester as a High-Affinity Selective Ligand for the Serotonin Transporter. Med. Chem. 40: 3861-3864, 1997.
  299. Koylu, E.O., Couceyro, P.R., Lambert, P.D., and Kuhar, M.J. Cocaine- and Amphetamine-Regulated Transcript Peptide Immunohistochemical Localization in the Rat Brain. J. Comp. Neurol. 391: 115-132, 1998.
  300. Keverline-Frantz K.I., Boja, J.W., Kuhar, M.J., Abraham, P., Burgess, J.P., Lewin, A.H., and Carroll, F.I. Synthesis and Ligand Binding of Tropane Ring Analogues of Paroxetine.  Med. Chem. 41: 247-257, 1998. Corrected:  Keverline-Frantz, K.I., Boja, J.W., Kuhar, M.J., Abraham, P., Burgess, J.P., Lewin, A.H., and Carroll, F.I. Synthesis and Ligand Binding of Tropane Ring Analogues of Paroxetine. J. Med. Chem. 48: 336, 2005.
  301. Persico, A.M., Reich, S., Henningfield, J.E., Kuhar, M.J., and Uhl, G.R. Parkinsonian Patients Report Blunted Subjective Effects of Methylphenidate. Clin. Psychopharmacol. 6: 54-63, 1998.
  302. Carroll, F.I., Lewin, A.H., and Kuhar, M.J. 3b-Phenyl-2b-Substituted Tropanes — An SAR Analysis.  Chem. Res. 8(1/2): 59-65, 1998.
  303. Houlihan, W.J., Boja, J.W., Kopajtic, T.A., Kuhar, M.J., Degrado, S.J., and Toledo, L. Positional Isomers and Analogs of Mazindol as Potential Inhibitors of the Cocaine Binding Site on the Dopamine Transporter Site.  Chem. Res. 8(1/2): 77-90, 1998.
  304. Lambert, P.D., Couceyro, P.R., McGirr, K.M., Dall Vechia, S.E., Smith, Y., and Kuhar, M.J. CART Peptides in the Central Control of Feeding and Interactions with Neuropeptide Y.  Synapse 29: 293-298, 1998.
  305. Couceyro, P., Paquet, M., Koylu, E., Kuhar, M.J., and Smith, Y. Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide Immunoreactivity in Myenteric Plexus Neurons of the Rat Ileum and Co-localization with Choline Acetyltransferase.  Synapse 30: 1-8, 1998.
  306. Boja, J.W., Carroll, F.I., Vaughan, R.A., Kopajtic, T., and Kuhar, M.J. Multiple Binding Sites for [125I]RTI-121 and Other Cocaine Analogs in Rat Frontal Cerebral Cortex.  Synapse 30: 9-17, 1998.
  307. Dworkin, S.I., Lambert, P., Sizemore, G.M., Carroll, F.I., and Kuhar, M.J. RTI-113 Administration Reduces Cocaine Self-administration at High Occupancy of Dopamine Transporter.  Synapse 30: 49-55, 1998.
  308. Kuhar, M. Neurotransmitter Transporters are NOT in the Synapse? Presented at INABIS ’98 – 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, December 7-16th.  Invited Symposium.  Available at URL http://www.mcmaster.ca/inabis98/simantov/kuhar0153/two.html, 1998.
  309. Elias, C.F., Lee, C., Kelly, J., Aschkenasi, C., Ahima, R.S., Couceyro, P.R., Kuhar, M.J., Saper, C.B., and Elmquist, J.K. Leptin Activates Hypothalamic CART Neurons Projecting to the Spinal Cord.  Neuron 21: 1375-1385, 1998.
  310. Jiang, S., Chang, A.-C., Abraham, P., Kuhar, M.J., and Carroll, F.I. Synthesis and Transporter Binding Properties of (R)-2b,3b- and (R)-2a,3a-diaryltropanes.  Med. Chem. Lett. 8: 3689-3692, 1998.
  311. Koylu, E.O., Smith, Y., Couceyro, P.R., and Kuhar, M.J. CART Peptides Colocalize with Tyrosine Hydroxylase Neurons in Rat Locus Coeruleus.  Synapse 31: 309-311, 1999.
  312. Ding, Y.-S., Molina, P.E., Fowler, J.S., Logan, J., Volkow, N.D., Kuhar, M.J., and Carroll, F.I. Comparative Studies of Epibatidine Derivatives [18F]NFEP and [18F]N-Methyl-NFEP: Kinetics, Nicotine Effect, and Toxicity.  Med. Biol. 26: 139-148, 1999.
  313. Zhong, D., Kotian, P., Wyrick, C.D., Seltzman, H.H., Kepler, J.A., Boja, J.W., Kuhar, M.J., and Carroll, F.I. Synthesis of 3b-(4-[125I]Iodophenyl)tropane-2b-pyrrolidine Carboxamide ([125I]RTI-229).   Labelled Compd. Radiopharmaceut. 42: 281-286, 1999.
  314. Smith, Y., Kieval, J., Couceyro, P.R., and Kuhar, M.J. CART Peptide-Immunoreactive Neurones in the Nucleus Accumbens in Monkeys: Ultrastructural Analysis, Colocalization Studies, and Synaptic Inter­actions with Dopaminergic Afferents. Comp. Neurol. 407: 491-511, 1999.
  315. Lambert, P.D., McGirr, K.M., Ely, T.D., Kilts, C.D., and Kuhar, M.J. Chronic Lithium Treatment Decreases Neuronal Activity in the Nucleus Accumbens and Cingulate Cortex of the Rat. Neuropsycho­pharmacology 21: 229-237, 1999.
  316. Garzón, M., Vaughan, R.A., Uhl, G.R., Kuhar, M.J., and Pickel, V.M. Cholinergic Axon Terminals in the Ventral Tegmental Area Target a Subpopulation of Neurons Expressing Low Levels of the Dopamine Transporter.  Comp. Neurol. 410: 197-210, 1999.
  317. Kuhar, M.J. and Yoho, L.L. CART Peptide Analysis by Western Blotting.  Synapse 33: 163-171, 1999.
  318. Kuhar, M.J., McGirr, K.M., Hunter, R.G., Lambert, P.D., Garrett, B.E., and Carroll, F.I. Studies of Selected Phenyltropanes at Monoamine Transporters.  Drug Alcohol Depend. 56: 9-15, 1999.
  319. Vicentic, A., Battaglia, G., Carroll, F.I., and Kuhar, M.J. Serotonin Transporter Production and Degradation Rates: Studies with RTI-76.  Brain Res. 841: 1-10, 1999.
  320. Broberger, C., Holmberg, K., Kuhar, M.J., and Hökfelt, T. Cocaine- and Amphetamine-Regulated Transcript in the Rat Vagus Nerve: A Putative Mediator of Cholecystokinin-Induced Satiety.  Natl. Acad. Sci. USA  96: 13506-13511, 1999.
  321. Javanmard, S., Deutsch, H.M., Collard, D.M., Kuhar, M.J., and Schweri, M.M. Synthesis and Pharma­cology of Site-Specific Cocaine Abuse Treatment Agents: 2-Substituted-6-amino-5-phenylbicyclo[2.2.2] octanes.  Med. Chem. 42: 4836-4843, 1999.
  322. Broberger, C., Visser, T.J., Kuhar, M.J., and Hökfelt, T. Neuropeptide Y Innervation and Neuropeptide-Y-Y1-Receptor-Expressing Neurons in the Paraventricular Hypothalamic Nucleus of the Mouse.  Neuroendocrinology 70: 295-305, 1999.
  323. Howell, L.L., Czoty, P.W., Kuhar, M.J., and Carroll, F.I. Comparative Behavioral Pharmacology of Cocaine and the Selective Dopamine Uptake Inhibitor RTI-113 in the Squirrel Monkey.  Pharmacol. Exp. Ther. 292: 521-529, 2000.
  324. Zhong, D., Blough, B.E., Kuhar, M.J., and Carroll, F.I. Synthesis of [125I]-3ß-(4-Ethyl-3-iodophenyl)nor­tropane-2ß-carboxylic Acid Methyl Ester ([125I]EINT).  Labelled Cpd. Radiopharm. 43: 137-146, 2000.
  325. Kimmel, H.L., Carroll, F.I., and Kuhar, M.J.: Dopamine Transporter Synthesis and Degradation Rate in Rat Striatum and Nucleus Accumbens Using RTI-76.  Neuropharmacology 39: 578-585, 2000.
  326. Dall Vechia, S., Lambert, P.D., Couceyro, P.C., Kuhar, M.J., and Smith, Y. CART Peptide Immuno­reactivity in the Hypothalamus and Pituitary in Monkeys: Analysis of Ultrastructural Features and Synaptic Connections in the Paraventricular Nucleus.  Comp. Neurol. 416: 291-308, 2000.
  327. Koylu, E.O., Weruaga, E., Balkan, B., Alonso, J.R., Kuhar, M.J., and Pogun, S. Co-localization of CART Peptide Immunoreactivity and Nitric Oxide Synthase Activity in Rat Hypothalamus.  Brain Res. 868: 352-357, 2000.
  328. Kimmel, H.L., Gong, W., Dall Vechia, S., Hunter, R.G., and Kuhar, M.J. Intra-ventral Tegmental Area Injection of Rat Cocaine and Amphetamine-Regulated Transcript Peptide 55-102 Induces Locomotor Activity and Promotes Conditioned Place Preference.  Pharmacol. Exp. Ther. 294: 784-792, 2000.
  329. Blough, B.E., Holmquist, C.R., Abraham, P., Kuhar, M.J., and Carroll, F.I. 3a-(4-Substituted Phenyl) nortropane-2-ß-carboxylic Acid Methyl Esters Show Selective Binding at the Norepinephrine Transporter.  Med. Chem. Lett. 10: 2445-2447, 2000.
  330. Fekete, C., Mihály, E., Luo, L.-G., Kelly, J., Clausen, J.T., Mao, Q., Rand, W.M., Moss, L.G., Kuhar, M., Emerson, C.H., Jackson , I.M., and Lechan, R.M. Association of Cocaine- and Amphetamine-Regulated Transcript-Immunoreactive Elements with Thyrotropin-Releasing Hormone-Synthesizing Neurons in the Hypothalamic Paraventricular Nucleus and Its Role in the Regulation of the Hypothalamic-Pituitary-Thyroid Axis during Fasting.  Neurosci. 20: 9224-9234, 2000.
  331. Wang, L.C., Berfield, J.L., Kuhar, M.J., Carroll, F.I., and Reith, M.E. RTI-76, an Isothiocyanate Derivative of a Phenyltropane Cocaine Analog, as a Tool for Irreversibly Inactivating Dopamine Trans­porter Function in Vitro.  Naunyn-Schmiedeberg’s Arch. Pharmacol. 362: 238-247, 2000.
  332. Murphy, K.G., Abbott, C.R., Mahmoudi, M., Hunter, R., Gardiner, J.V., Rossi, M., Stanley, S.A., Ghatei, M.A., Kuhar, M.J., and Bloom, S.R. Quantification and Synthesis of Cocaine- and Amphetamine-Regulated Transcript Peptide (79-102)-like Immunoreactivity and mRNA in Rat Tissues.  Endocrinol. 166: 659-668, 2000.
  333. Johansen, J.E., Broberger, C., Lavebratt, C., Johansson, C., Kuhar, M.J., Hökfelt, T., and Schalling, M. Hypothalamic CART and Serum Leptin Levels are Reduced in the Anorectic (anx/anx) Mouse. Brain Res. 84: 97-105, 2000.
  334. Kimmel, H., Vicentic, A., and Kuhar, M.J. Neurotransmitter Transporters: Synthesis and Degradation Rates. Life Sci. 68: 2181-2185, 2001.
  335. Dall Vechia-Adams, S., Smith, Y., and Kuhar, M.J. CART Peptide-Immunoreactive Projection from the Nucleus Accumbens Targets Substantia Nigra Pars Reticulata Neurons in the Rat.  Comp. Neurol. 434: 29-39, 2001.
  336. Kuhar, M.J., Joyce, A., and Dominguez, G. Genes in Drug Abuse.  Drug Alcohol Depend. 62: 157-162, 2001.
  337. Elias, C.F., Lee, C.E., Kelly, J.F., Ahima, R.S., Kuhar, M., Saper, C.B., and Elmquist, J.K. Characteri­zation of CART Neurons in the Rat and Human Hypothalamus. Comp. Neurol. 432: 1-19, 2001.
  338. Kuhar, M.J., Carroll, F.I., Bharat, N., and Landry, D.W. Anticocaine Catalytic Antibodies have no Affinity for RTI Compounds: Implications for Treatment.  Synapse 41: 176-178, 2001.
  339. Kimmel, H.L., Joyce, A.R., Carroll, F.I., and Kuhar, M.J. Dopamine D1 and D2 Receptors Influence Dopamine Transporter Synthesis and Degradation in the Rat.  Pharmacol. Exp. Ther. 298: 129-140, 2001.
  340. Navarro, H.A., Xu, H., Zhong, D., Blough, B.E., Ross, W.P., Kuhar, M.J., and Carroll, F.I. [125I]3ß-(4-Ethyl-3-iodophenyl)nortropane-2ß-carboxylic Acid Methyl Ester ([125I]EINT): A Potent and Selective Radioligand for the Brain Serotonin Transporter.  Synapse 41: 241-247, 2001.
  341. Wu, Q., Reith, M.E.A., Kuhar, M.J., Carroll, F.I., and Garris, P.A. Preferential Increases in Nucleus Accumbens Dopamine after Systemic Cocaine Administration are Caused by Unique Characteristics of Dopamine Neurotransmission.  Neurosci. 21: 6338-6347, 2001.
  342. Kuhar, M.J. and Joyce, A.R. Slow Onset of CNS Drugs: Can Changes in Protein Concentration Account for the Delay?  Trends Pharmacol. Sci. 22: 450-456, 2001.
  343. Stanley, S.A., Small, C.J., Murphy, K.G., Rayes, E., Abbott, C.R., Seal, L.J., Morgan, D.G.A., Sunter, D., Dakin, C.L., Kim, M.S., Hunter, R., Kuhar, M., Ghatei, M.A., and Bloom, S.R. Actions of Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide on Regulation of Appetite and Hypothalamo-Pituitary Axes In Vitro and In Vivo in Male Rats.  Brain Res. 893: 186-194, 2001.
  344. Kimmel, H.L., Carroll, F.I., and Kuhar, M.J. RTI-76, an Irreversible Inhibitor of Dopamine Transporter Binding, Increases Locomotor Activity in the Rat at High Doses.  Brain Res. 897: 157-163, 2001.
  345. Kimmel, H.L., Carroll, F.I., and Kuhar, M.J. Locomotor Stimulant Effects of Novel Phenyltropanes in the Mouse.  Drug Alcohol Depend. 65: 25-36, 2001.
  346. Balkan, B., Koylu, E.O., Kuhar, M.J., and Pogun, S. The Effect of Adrenalectomy on Cocaine and Amphetamine-Regulated Transcript (CART) Expression in the Hypothalamic Nuclei of the Rat.  Brain Res. 917: 15-20, 2001.
  347. Aja, S., Schwartz, G.J., Kuhar, M.J., and Moran T.H. Intracerebroventricular CART Peptide Reduces Rat Ingestive Behavior and Alters Licking Microstructure.  J. Physiol. Regul. Integr. Comp. Physiol. 280: R1613-R1619, 2001.
  348. Coons, S., Javanmard, S., Collard, D.M., Kuhar, M.J., Schweri, M.M., and Deutsch, H.M. Synthesis and Pharmacology of Potential Site-Specific Cocaine Abuse Treatment Agents: The Role of the Phenyl Group in 2-substituted-6-aminobicyclo[2.2.2]octanes.  Chem. Res. 11: 24-38, 2002.
  349. Lakatos, A., Dominguez, G., and Kuhar, M.J. CART Promoter CRE Site Binds Phosphorylated CREB.  Brain Res. 104: 81-85, 2002.
  350. Dominguez, G., Lakatos, A., and Kuhar, M.J. Characterization of the Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide Gene Promoter and Its Activation by a Cyclic AMP-Dependent Signaling Pathway in GH3 Cells.  Neurochem. 80: 885-893, 2002.
  351. Kimmel, H.L., Thim, L., and Kuhar, M.J. Activity of Various CART Peptides in Changing Locomotor Activity in the Rat.  Neuropeptides 36: 9-12, 2002.
  352. Dallvechia-Adams, S., Kuhar, M.J., and Smith, Y. Cocaine- and Amphetamine-Regulated Transcript Peptide Projections in the Ventral Midbrain: Colocalization with γ-Aminobutyric Acid, Melanin-Concentrating Hormone, Dynorphin, and Synaptic Interactions with Dopamine Neurons. J. Comp. Neurol. 448: 360-372, 2002.
  353. Blough, B.E., Keverline, K.I., Nie, Z., Navarro, H., Kuhar, M.J., and Carroll, F.I. Synthesis and Transporter Binding Properties of 3ß-[4’-(Phenylalkyl, -phenylalkenyl, and –phenylalkynl)-phenyl]tropane-2ß-carboxylic Acid Methyl Esters: Evidence of a Remote Phenyl Binding Domain on the Dopamine Transporter.  Med. Chem. 45: 4029-4037, 2002.
  354. Kimmel, H.L., Carroll, F.I., and Kuhar, M.J. Withdrawal from Repeated Cocaine Alters Dopamine Transporter Protein Turnover in the Rat Striatum.  Pharmacol. Exp. Ther. 304: 15-21, 2003.
  355. Kuhar, M.J. and Joyce, A.R. Is the Onset of Psychoactive Drug Effects Compatible with a Protein-Synthesis Mechanism?  Neuropsychopharmacology 28: 594-597, 2003.
  356. Balkan, B., Koylu, E., Pogun, S., and Kuhar, M.J. Effects of Adrenalectomy on CART Expression in the Rat Arcuate Nucleus.  Synapse 50: 14-19, 2003.
  357. Damaj, M.I., Martin, B.R., and Kuhar, M.J. Antiociceptive Effects of Supraspinal Rat Cart (55-102) Peptide in Mice.  Brain Res. 983: 233-236, 2003.
  358. Ekblad, E., Kuhar, M., Wierup, N., and Sundler, F. Cocaine- and Amphetamine-Regulated Transcript: Distribution and Function in Rat Gastrointestinal Tract. Neurogastroenterol. Motil. 15: 545-557, 2003.
  359. Jaworski, J.N., Kozel, M.A., Philpot, K.B., and Kuhar M.J. Intra-accumbal Injection of CART (Cocaine-Amphetamine Regulated Transcript) Peptide Reduces Cocaine-Induced Locomotor Activity.  Pharmacol. Exp. Ther. 307: 1038-1044, 2003.
  360. Wierup, N., Kuhar, M., Nilsson, B.O., Mulder, H., Ekblad, E., and Sundler, F. Cocaine- and Amphetamine-Regulated Transcript (CART) is Expressed in Several Islet Cell Types during Rat Development.  Histochem. Cytochem. 52: 169-177, 2004.
  361. Carroll, F.I., Pawlush, N., Kuhar, M.J., Pollard, G.T., and Howard, J.L. Synthesis, Monoamine Transporter Binding Properties, and Behavioral Pharmacology of a Series of 3ß-(substituted phenyl)-2ß-(3’-substituted isoxazol-5-yl)tropanes.  Med. Chem. 47: 296-302, 2004.
  362. Kuriyama, G., Takekoshi, S., Tojo, K., Nakai, Y., Kuhar, M.J., and Osamura, R.Y. Cocaine- and amphetamine-regulated transcript peptide in the rat anterior pituitary gland is localized in gonadotrophs and suppresses prolactin secretion. Endocrinology 145: 2542-2550, 2004.
  363. 359.Dominguez, G. and Kuhar, M.J.  Transcriptional Regulation of the CART Promoter in CATH.a Cells.  Mol. Brain Res. 126: 22-29, 2004.
  364. 360.Vicentic, A., Dominguez, G., Hunter, R.G., Philpot, K., Wilson, M., and Kuhar, M.J.  Cocaine- and Amphetamine-Regulated Transcript Peptide Levels in Blood Exhibit a Diurnal Rhythm: Regulation by Glucocorticoids. Endocrinology 145: 4119-4124, 2004.
  365. 361.Choi Y.H., Della-Fera, M.A., Li, C., Hartzell, D.L., Little, D.E., Kuhar, M.J., and Baile, CA. CART Peptide: Central Mediator of Leptin-Induced Adipose Tissue Apoptosis? Reg. Peptides 121: 155-162, 2004.
  366. 362.Damaj, M.I., Hunter, R.G., Martin, B.R., and Kuhar, M.J.  Intrathecal CART (55-102) Enhances the Spinal Analgesic Actions of Morphine in Mice.  Brain Res. 1024: 146-149, 2004.
  367. 363.Dominguez, G., del Giudice, E.M., and Kuhar, M.J.  CART Peptide Levels are Altered by a Mutation Associated with Obesity at Codon 34. Mol. Psychiatry 9: 1065-1066, 2004.
  368. Carroll, F.I., Runyon, S.P., Abraham, P., Navarro, H., Kuhar, M.J., Pollard, G.T., and Howard, J.L. Monoamine Transporer Binding, Lactivity, and Drug Discrimination Properties of 3-(4-Substituted-phenyl)ropane-2-Carboxylic Acid Methyl Ester Isomers. Med. Chem. 47: 6401-6409, 2004.
  369. Vicentic, A., Lakatos, A., Hunter, R., Philpot, K., Dominguez, G., and Kuhar, M.J. CART Peptide Diurnal Rhythm in Brain and Effect of Fasting.  Brain Res. 1032: 111-115, 2005.
  370. Vicentic, A., Hunter, R.G., and Kuhar, M.J. Effect of Corticosterone on CART Peptide Levels in Rat Blood. Peptides 26: 531-533, 2005.
  371. Runyon, S.P., Burgess, J.P., Abraham, P., Keverline-Frantz, K.I., Flippen-Anderson, J., Deschamps, J,, Lewin, A.H., Navarro, H.A., Boja, J.W., Kuhar, M.J., and Carroll, F.I. Synthesis, Structural Identification, and Ligand Binding of Tropane Ring Analogs of Paroxetine and an Unexpected Aza-bicyclo[3.2.2]nonane Rearrangement Product.  Med. Chem. 13: 2439-2449. 2005.
  372. Carroll, F.I., Blough, B.E., Nie, Z., Kuhar, M.J., Howell, L.L., and Navarro, H.A. Synthesis and Monoamine Transporter Binding Properties of 3β-(3’,4’-Disubstituted phenyl)tropane-2β-carboxylic Acid Methyl Esters. J. Med. Chem. 48: 2767-2771, 2005.
  373. Lakatos, A., Prinster, S., Vicentic, A., Hall, R.A., and Kuhar, M.J. Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide Activates the Extracellular Signal-Regulated Kinase (ERK) Pathway in AtT20 Cells via Putative G-Protein Coupled Receptors.  Lett. 384: 198-202, 2005.
  374. Wierup, N., Richards, W.G., Bannon, A.W., Kuhar, M.J., Ahren, B., and Sundler, F. CART Knock Out Mice have Impaired Insulin Secretion and Glucose Intolerance, Altered Beta Cell Morphology and Increased Body Weight.  Pept. 129: 203-211, 2005.
  375. Hubert, G.W. and Kuhar, M.J. Colocalization of CART with Substance P but Not Enkephalin in the Rat Nucleus Accumbens.  Brain Res. 1050: 8-14, 2005.
  376. Hunter, R.G., Vicentic, A., Rogge, G., and Kuhar, M.J. The Effects of Cocaine on CART Expression in the Rat Nucleus Accumbens: A Possible Role for Corticosterone. Eur. J. Pharmacol. 517: 45-50, 2005.
  377. Vicentic, A., Lakatos, A., and Kuhar, M.J. CART (Cocaine- and Amphetamine-Regulated Transcript) Peptide Receptors:  Specific Binding in AtT20 Cells.  J. Pharm. 528: 188-189, 2005.
  378. Carroll, F.I., Tyagi, S., Blough, B.E., Kuhar, M.J., and Navarro, H.A. Synthesis and Monoamine Transporter Binding Properties of 3α-(Substituted phenyl)nortropane-2ß-carboxylic Acid Methyl Esters.  Norepinephrine Transporter Selective Compounds.  Med. Chem. 48: 3852-3857, 2005.
  379. 375.Hemby, S.E., Tang, W., Muly, E.C., Kuhar, M.J., Leonard L., and Mash, D.C.  Cocaine-Induced Alterations in Nucleus Accumbens Ionotropic Glutamate Receptor Subunits in Human and Non-Human Primates.  J. Neurochem. 95: 1785-1793, 2005.
  380. 376.Kotturi, S.V., Jiang, S., Chang, A.C., Abraham, P., Navarro, H.A., Kuhar, M.J., and Carroll, F.I. Synthesis and Monoamine Transporter Binding Properties of 2,3-Diaryltropanes. J. Med Chem. 48: 7437-7444, 2005.
  381. 377.Philpot, K.B., Dallvechia-Adams, S., Smith, Y., and Kuhar, M.J. A Cocaine-and Amphetamine-Regulated-Transcript Peptide Projection from the Lateral Hypothalamus to the Ventral Tegmental Area.  Neuroscience 135: 915-925, 2005.
  382. 378.Osei-Hyiaman, D., Depetrillo, M., Harvey-White, J., Bannan, A., Cravatt, B.F., Kuhar, M.J., Mackie, K., Palkovits, M., and Kunos, G. Cocaine- and Amphetamine-Related Transcript is Involved in the Orexigenic Effect of Endogenous Anandamine. Neuroendocrinology 81: 273-282, 2005.
  383. 379.Hunter, R.G., Lim, M.M., Philpot, K.B., Young, L.J., and Kuhar, M.J. Species Differences in Brain Distribu­tion of CART mRNA and CART Peptide between Prairie and Meadow Voles. Brain Res. 1048: 12-23, 2005.
  384. 380.Jaworski, J.N., Francis, D.D., Brommer, C.L., Morgan, E.T., and Kuhar, M.J.  Effects of Early Maternal Separation on Ethanol Intake, GABA Receptors and Metabolizing Enzymes in Adult Rats. Psychopharmacology (Berl.) 181: 8-15, 2005.
  385. 381.Wierup, N., Bjorkgvist, M., Kuhar, M.J., Mulder, H., and Sundler, F. CART Regulates Islet Hormone Secretion and Is Expressed in the β-Cells of Type 2 Diabetic Rats. Diabetes 55: 305-311, 2006.
  386. 382.Yanik, T., Dominguez, G., Kuhar, M.J., del Giudice, E.M., and Loh Y.P. The Leu34Phe ProCART Mutation Leads to Cocaine- and Amphetamine-Regulated Transcript (CART) Deficiency: A Possible Cause for Obesity in Humans. Endocrinology 147: 39-43, 2006.
  387. 383.del Giudice, EM, E., Santoro, N., Fiumani, P., Dominguez, G., Kuhar, M.J., and Perrone, L. Adolescents Carrying a Missense Mutation in the CART Gene Exhibit Increased Anxiety and Depression. Depress. Anxiety 23: 90-92, 2006.
  388. Joyce, A.R., Easterling, K., Holtzman, S.G., and Kuhar, M.J. Modeling the Onset of Drug Dependence: A Consideration of the Requirement for Protein Synthesis. J. Theor. Biol. 240: 531-537, 2006.
  389. Imad Damaj, M., Zheng, J., Martin, B.R., and Kuhar, M.J. Intrathecal CART (55-102) Attenuates Hyper­lagesia and Allodynia in a Mouse Model of Neuropathic but not Inflammatory Pain. Peptides 27: 2019-2023, 2006.
  390. Balkan, B., Gozen, O., Yararbas, G., Koylu, E.O., Akinturk, S., Kuhar, M.J., and Pogun, S. CART Expression in Limbic Regions of Rat Brain following Forced Swim Stress: Sex Differences. Neuropeptides 40: 185-193, 2006.
  391. Vicentic, A., Francis, D., Moffett, M., Lakatos, A., Rogge, G., Hubert, G.W., Harley, J., and Kuhar, M.J. Maternal Separation Alters Serotonergic Transporer Densities and Serotonergic 1A Receptors in Rat Brain. Neuroscience 140: 355-365, 2006.
  392. Moffett, M.C., Harley, J., Francis, D., Sanghani, S.P., Davis, W.I., and Kuhar, M.J. Maternal Separation and Handling Affects Cocaine Self-administration in Both the Treated Pups as Adult and the Dams. J. Pharmaol. Exp. Ther. 317: 1210-1218, 2006.
  393. Hunter, R.G., Jones, D., Vicentic, A., Hue, G., Rye, D., and Kuhar, M.J. Regulation of CART mRNA in the Rat Nucleus Accumbens via D3 Dopamine Receptors. Neuropharmacology 50: 858-864, 2006.
  394. Hubert, G.W. and Kuhar, M.J. Colocalization of CART Peptide with Prodynorphin and Dopamine D1 Receptors in the Rat Nucleus Accumbens. Neuropeptides 40: 409-415, 2006.
  395. Moffett, M., Stanek, L., Harley, J., Rogge, G., Asnicar, M., Hsiung, H., and Kuhar, M. Studies of Cocaine- and Amphetamine-Regulated Transcript (CART) Knockout Mice. Peptides 27: 2037-2045, 2006.
  396. Carroll, F.I., Fox B.S., Kuhar, M.J., Howard, J.L., Pollard, G.T., and Schenk, S. Effects of Dopamine Transporter Selective 3-Phenyltropane Analogs on Locomotor Activity, Drug Discrimination, and Cocaine Self-administration after Oral Administration. Eur. J. Pharmacol.: 553(1-3): 149-156, 2006.
  397. Jones, DC and Kuhar, MJ. Cocaine-amphetamine-regulated transcript expression in the rat nucleus accumbens is regulated by adenylyl cyclase and the cyclic adenosine 5′-monophosphate/protein kinase a second messenger system. J Pharmacol Exp Ther. 317(1):454-61., 2006.  PMID 16322355.
  398. 394.Jaworski, N.J., Kimmel, H.L., Mitrano, D.A., Tallarida, R.J., and Kuhar, M.J.  Intra-VTA CART 55-102 Reduces the Locomotor Effect of Systemic Cocaine in Rats: An Isobolographic Analysis. Neuropeptides 41: 65-72, 2007.  PMID 17289142.
  399. 395.Gozen, O., Balkan, B., Yararbas, G., Koylu, E.O., Kuhar, M.J., and Pogun, S. Sex Differences in the Regulation of Cocaine and Amphetamine-Regulated Transcript Expression in Hypothalamic Nuclei of Rats by Forced Swim Stress. Synapse 61: 561-568, 2007.  PMID 17447258.
  400. Gong PK, Blough BE, Brieaddy LE, Hunag X, Kuhar MJ, Navarro HA, and Carroll FI. Synthesis, monoamine transporter binding, properties and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2beta-[5-substitutes phenyl) thiazol-2-yl]tropanes. J Med Chem 50:3686-95, 2007. PMID 17602602.
  401. Gunnarsdottir A, Wierup N, Larsson LT, Kuhar MJ, Ekblad E. CART-peptide immunoreactivity in enterix nerves in patients with Hirschsprung’s disease.  Eur J Pediatr Surg 17:184-9, 2007.  PMID 17638157.
  402. Keating GL, Kuhar MJ, Rye DB. High dose CART peptide induces abnormal EEG activity and behavioral seizures.  Neuropeptides. 42:199-204, 2008. PMID 18178249.
  403. Jones DC, Kuhar MJ. CART receptor binding in primary cell cultures of the rat nucleus accumbens.  Synapse. Feb;62(2):122-7. 2008. PMID 18000808.
  404. van der Burg JM, Bacos K, Wood NI, Lindqvist A, Wierup N, Woodman B, Wamsteeker JI, Smith R, Deierborg T, Kuhar MJ, Bates GP, Mulder H, Erlanson-Albertsson C, Morton AJ, Brundin P, Petersén A, Björkqvist M. Increased metabolism in the R6/2 mouse model of Huntington’s disease.  Neurobiol Dis. Jan;29(1):41-51. 2008  PMID 17920283.
  405. Jaworski JN, Hansen ST, Kuhar MJ, Mark GP. Injection of CART peptide into the nucleus accumbens reduces cocaine self-administration in the rat.  Behav Brain Res  191:266-271, 2008.  PMID: 18485497.
  406. Francis DD and Kuhar MJ. Frequency of maternal licking and grooming correlates negatively with vulnerability to cocaine and alcohol use in rats. Pharmacol Biochem Behav 90:497-500, 2008.  PMID:18271022
  407. Hubert GW and Kuhar MJ. Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos.  Neuropeptides 42:339-43, 2008.  PMID18314190.
  408. Lima FB, Henderson JA, Reddy AP, Tokuyama Y, Hubert GW, Kuhar MJ, Bethea CL. Unique responses of midbrain CART neurons in macaques to ovarian steroids.  Brain Res 1227:76-88, 2008.  PMID 18598674.
  409. Bartell SM, Isales CM, Baile CA, Kuhar MJ, Hamrick MW. CART deficiency increases body weight but does not alter bone strength.  J Musculoskelet Neuronal Interact 8:151-158, 2008.  PMID 18622083.
  410. Rogge GA, Jones DC, Green T, Nestler E, and Kuhar MJ. Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo. Brain Res 1251:42-52, 2009.  PMID 19046951.
  411. Jones DC, Lakatos A, Rogge GA, Kuhar MJ. Regulation of CART mRNA expression by calcium-mediated signaling in GH3 cells. 160(2):339-347, 2009.  PMID 19258027
  412. Hubert GW, Manvich DF, Kuhar MJ. Cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion. 165(1):179-187, 2010  PMID: 19825396
  413. Kuhar, MJ. Measuring levels of proteins by various technologies: can we learn more by measuring turnover?  Biochem Pharmacol.  79(5):665-8, 2010.  PMID: 19814998
  414. Keating, GL, Kuhar MJ, Bliwise DL, and Rye DB. Wake-promoting effects of cocaine and amphetamine –regulated transcript. 44(3):241-246, 2010.  PMID:20116848
  415. Rogge GA, Shen LL, and Kuhar MJ. Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter.  Brain Res ­1344:1-12, 2010.  PMID:20451507
  416. Moffett MC, Song J, and Kuhar, MJ. CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors.  Synapse  Jan; 65(1):1-7, 2011.  PMID:20506412. PMCID: PMC2939215.
  417. Lin Y, Hall RA, Kuhar MJ. CART peptide stimulation of G protein-mediated signaling in differentiated PC12 Cells: Identification of PACAP 6-38 as a CART receptor antagonist.    2011, 45:351-358.  PMID: 21855138. PMCID: PMC3170513.
  418. Brennan DJ, O’Connor DP, Laursen H, McGee SF, McCarthy S, Zagozdzon R, Rexhepaj E, Culhane AC, Martin FM, Duffy MJ, Landberg G, Ryden L, Hewitt SM, Kuhar MJ, Bernards R, Millikan RC, Crown JP, Jirström K, Gallagher WM. The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast cancer. 2012 Jul 26;31(30):3483-94. doi: 10.1038/onc.2011.519. Epub 2011 Dec 5.  PMID: 22139072
  419. Balkan B, Keser A, Gozen O, Koylu EO, Dagci T, Kuhar MJ, Pogun S. Forced swim stress elicits region-specific changes in CART expression in the stress axis and stress regulatory brain areas. Brain Res. 2012 Jan 13;1432:56-65. Epub 2011 Nov 9.  PMID: 22137563
  420. Job MO, Licata J, Hubert GW, Kuhar MJ. Intra-accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats. Brain Res. 2012 Oct 30;1482:47-54. PMID: 22975438. PMCID:PMC3487597.
  421. Balkan B, Gozen O, Koylu EO, Keser A, Kuhar MJ, Pogun S. Region- and sex-specific changes in CART mRNA in rat hypothalamic nuclei induced by forced swim stress. Brain Res. 2012 Oct 15;1479:62-71. PMID: 22960117.  PMCID: PMC3468742.
  422. Job MO and Kuhar MJ. Intraperitoneal Administration of CART-55-102 Inihbits Psychostimulant-Induced Locomotion. J Drug and Alcohol Res. 2012 January 1;1. Doi:10.4303/jdar/235601. PMCID: PMC3659824
  423. Job MO, Shen LL, Kuhar MJ. The inhibition of cocaine-induced locomotor activity by CART 55-102 is lost after repeated cocaine administration. Neurosci Lett. 2013 Jun 29. doi:pii: S0304-3940(13)00586-7. 10.1016/j.neulet.2013.06.039. [Epub ahead of print]. PMID: 23819981. PMCID: PMC3901563
  424. Wong FC, Boja J, Ho B, Kuhar MJ, Wong DF. Affinity labeling of membrane receptors using tissue-penetrating radiations. Biomed Res Int. 2013;2013:503095. doi: 10.1155/2013/503095. Epub 2013 Jun 27. PMID: 23936811. PMCID: PMC3712212.
  425. Job MO, Perry J, Shen LL, Kuhar MJ. CART peptide attenuates dopamine and cocaine mediated locomotor activity in both male and female rats. Lack of sex differences. Neuropeptides. 2014 48(2):75-81. PMID: 24630272. PMCID: PMC4023686. 

 

BOOK CHAPTERS, REVIEWS AND OTHER

  1. Snyder, S.H., Kuhar, M.J., Green, A.I., Coyle, J.T., and Shaskan, E.G. Uptake and Subcellular Localization of Neurotransmitters in the Brain.  Rev. Neurobiol., Vol. 13, C.C. Pfeiffer and J.R. Smythies (Eds.), Academic Press, New York, pp. 127‑158, 1970.
  2. Snyder, S.H., Shaskan, E.G., and Kuhar, M.J. Serotonin Uptake Systems in Brain Tissue.   In:  Serotonin and Behavior, J. Barchas and E. Usdin (Eds.).  Academic Press, New York, pp. 97-108, 1973.
  3. Aghajanian, G.K., Bunney, B.S., and Kuhar, M.J. Use of Single Unit Recording in Correlating Transmitter Turnover with Impulse Flow in Monoamine Neurons.  In: New Concepts in Neurotransmitter Regulation, A.J. Mandel (Ed.).  Plenum Publ. Corp., New York, pp. 115‑134, 1973.
  4. Kuhar, M.J. Neurotransmitter Uptake: A Tool in Identifying Neurotransmitter‑Specific Pathways.  Life Sci. 13: 1623‑1634, 1973.
  5. Kuhar, M.J., Aghajanian, G.K., and Roth, R.H. Serotonin Neurons: A Synaptic Mechanism for the Reuptake of Serotonin.  In: Advances in Biochemical Pharmacology, Vol. 10, E. Costa, G.L. Gessa and M. Sandler (Eds.).  Raven Press, New York, pp. 287‑295, 1974.
  6. Kuhar, M.J. Cholinergic Neurons: Septal-Hippocampala Relationships.  In: The Hippocampus, Vol. 1, R.L. Isaacson and K.H. Pribram (Eds.).  Plenum Publ. Cor., New York, pp. 269-283, 1975.
  7. Kuhar, M.J., Simon, J.R., and Rommelspacher, H. Studies of Central Cholinergic Neurons.  In: Current Developments in Psychopharmacology, Vol. II, W.B. Essman and L. Valzelli (Eds.). Spectrum Publ., Inc., Holliswood, NY, pp. 3-27, 1975.
  8. Kuhar, M.J. The Anatomy of Cholinergic Neurons.  In: Biology of Cholinergic Function, A.M. Goldberg and I. Hanin (Eds.).  Raven Press, New York, pp. 3-28, 1976.
  9. Bird, S.J., Atweh, S.F., and Kuhar, M.J. Microiontophoretic Study of the Effects of Opiates on Autoradio­graphically Localized Opiate Receptors.  In: Opiates and Opioid Peptides, H. Kosterlitz (Ed.). Elsevier/ North-Holland Biomedical Press, Amsterdam, pp. 199‑204, 1976.
  10. Pert, C.B., Snyder, S.H., and Kuhar, M.J. Opiate Receptor Binding in Intact Animals.  In: Tissue Response to Addictive Drugs, D.H. Ford and D.H. Clouet (Eds.).  Spectrum Publ., Inc., Holliswood, New York, pp. 89‑101, 1976.
  11. Kuhar, M.J. and Murrin, L.C. Sodium‑Dependent High Affinity Choline Uptake (A Review). J. Neurochem. 30: 15‑21, 1978.
  12. Kuhar, M.J. and Atweh, S.F. Distribution of Some Suspected Neurotransmitters in the CNS. Rev. Neurosci. 3: 35‑76, 1978.
  13. Kuhar, M.J. Histochemical Localization of Opiate Receptors and Opioid Peptides.  Proc. 37: 153‑157, 1978.
  14. Kuhar, M.J., Atweh, S.F., and Bird, S.J. Studies of Cholinergic‑Monoaminergic Interactions in Rat Brain.  In: Cholinergic‑Monoaminergic Interactions in the Brain, L.L. Butcher (Ed.). Aademic Press, San Francisco, pp. 211‑227, 1978.
  15. Kuhar, M.J. Autoradiographic Localization of Receptor Sites in the CNS in vivoIn: Psycho­pharma­cology: A Generation of Progress, M.A. Lipton, A. DiMascio and K.F. Killam (Eds.). Raven Press, New York, pp. 371‑376, 1978.
  16. Kuhar, M.J. Opiate Receptors: Some Anatomical and Physiological Aspects.  N.Y. Acad. Sci. 311: 35‑48, 1978.
  17. Kuhar, M.J. Central Cholinergic Pathways: Physiologic and Pharmacologic Aspects.  In: Psychopharma­cology: A Generation of Progress, M.A. Lipton, A. DiMascio, and K.F. Killam (Eds.).  Raven Press, New York, pp. 199‑203, 1978.
  18. Kuhar, M.J. Characteristics and Significance of Sodium‑Dependent, High Affinity Choline Uptake.  In: Cholinergic Mechanisms and Psychopharmacology, D. Jenden (Ed.).  Plenum Publ. Corp., New York,  447‑456, 1978.
  19. Kuhar, M.J. and Uhl, G.R. Histochemical Localization of Opiate Receptors and the Enkephalins. In: Neuro­chemical Mechanisms of Opiate Action, D.H. Ross and H.H. Loh (Eds.).  Raven Press, New York, pp. 53‑68, 1978.
  20. Uhl, G.R., Goodman, R.R., Kuhar, M.J., and Snyder, S.H. Enkephalin and Neurotensin: Immunohisto­chemical Localization and Identification of an Amygdalofugal Pathway. In: Advances in Biochemical Psycho­pharmacology, Vol. 18, E. Costa and M. Trabucchi (Eds.).  Raven Press, New York, pp. 71‑87, 1978.
  21. Kuhar, M.J. Histochemical Localization of Neurotransmitter Receptors.  In: Neurotransmitter Receptor Binding, H.I. Yamamura, S.J. Enna, and M.J. Kuhar (Eds.).  Raven Press, New York, pp. 113‑126, 1978.
  22. Young, W.S., III, and Kuhar, M.J. Opiate Receptor Autoradiography: In vitro Labeling of Tissue    In: Characteristics and Function of Opioids, J.M. VanRee and L. Terenius (Eds.).  Elsevier/North Holland Biomedical Press, Amsterdam, pp. 451‑452, 1978.
  23. Snyder, S.H., Uhl, G.R., and Kuhar, M.J. Comparative Features of Enkephalins and Neurotensin in the Mammalian Central Nervous System.  In: Centrally Acting Peptides, J. Hughes (Ed.).  University Park Press, Baltimore, pp. 85‑97, 1978.
  24. Murrin, L.C., Klemm, N. and Kuhar, M.J. Autoradiographic Localization of Dopamine and Neuroleptic Receptors in the Rat Brain Using 3H‑Spiperone.  In: Catecholamines: Basic and Clinical Frontiers, E. Usdin, I. Kopin and J. Barchas (Eds.).  Pergamon Press, New York, pp. 598‑600, 1978.
  25. Kuhar, M.J. Sodium‑Dependent High Affinity Choline Uptake.  In: The Cholinergic Synapse, S. Tucek (Ed.).  Brain Res. 49: 71‑76, 1979.
  26. Kuhar MJ, Uhl GR. Histochemical localization of opiate receptors and the enkephalins. Adv Biochem Psychopharmacol. 1979;20:53-68. Review. PMID:224662
  27. Young, W.S., III, and Kuhar, M.J. Opioid Receptor Autoradiography in Brains of Humans and Animals.  In: Endogenous and Exogenous Opiate Agonists and Antagonists, E.L. Way (Ed.).  Pergamon Press, New York, pp. 131‑134, 1980.
  28. Young, W.S., III, Palacios, J.M., and Kuhar, M.J. Histochemistry of Receptors.  In: Receptors for Neuro­transmitters and Peptide Hormones, G. Pepeu, M.J. Kuhar and S.H. Enna (Eds.).  Raven Press, New York, pp. 51‑56, 1980.
  29. Kuhar MJ. The benzodiazepine receptor: anatomical aspects. NIDA Res Monogr. 1980;(33):12-21. PMID:6275269
  30. Wamsley, J.K., Young, W.S., III, and Kuhar, M.J. Anatomical Localization of Enkephalin Immuno­reactive Sites in Rat Forebrain.  In: Neural Peptides and Neuronal Communication, E. Costa and M. Trabucchi (Eds.). Raven Press, New York, pp. 257‑270, 1980.
  31. Palacios, J.M., Young, W.S., III, and Kuhar, M.J. GABA and Benzodiazepine Receptors in Rat and Human Brain: Autoradiographic Localization by a Novel Technique.  In: Enzymes and Neurotransmitters in Mental Disease, E. Usdin, T.L. Sourkes and M.B.H. Youdin (Eds.).  John Wiley and Sons, New York, pp. 573‑583, 1980.
  32. Kuhar, M.J., Young, W.S., III, Palacios, J.M., and Wamsley, J.K. Radiohistochemical Studies of Drug  and Neurotransmitter Receptors in Brain.  In: Psychopharmacology and Biochemistry of Neurotransmitter Receptors (Developments in Neuroscience, Vol. 11), H.I. Yamamura, R.W. Olsen and E. Usdin (Eds.).  Elsevier/North Holland, Inc., New York, pp. 357‑368, 1980.
  33. Kuhar, M.J. Autoradiographic Localization of Drug and Neurotransmitter Receptors in the Brain.  Trends Neurosci. 4: 60‑64, 1981.
  34. Palacios, J.M., Unnerstall, J.R., Young, W.S., III, and Kuhar, M.J. Radiohistochemical Studies of Benzo­diazepine and GABA Receptors and Their Interactions.  In: GABA and Benzodiazepine Receptors, E. Costa, G. DiChiara and G.L. Gessa (Eds.).  Biochem. Psychopharm. Vol. 26, (E. Costa and P. Greengard, Series Eds.).  Raven Press, New York, pp. 53‑60, 1981.
  35. Palacios, J.M., Wamsley, J.K., Zarbin, M.A., and Kuhar, M.J. GABA and Glycine Receptors in Rat Brain: Autoradiographic Localization.  In: Amino Acid Neurotransmitters, F.V. DeFeudis and P. Mandel (Eds.). Adv. Biochem. Psychopharm. Vol. 29, (E. Costa and P. Greengard, Series Eds.). Raven Press, New York, pp. 445‑451, 1981.
  36. Frost, J.J. and Kuhar, M.J. In vitro and in vivo Labeling of Neurotransmitter Receptors.  In: Radio­pharmaceu­ticals:  Structure‑Activity Relationships, R.P. Spencer (Ed.). Grune and Stratton, New York, pp. 595‑618, 1981.
  37. Wamsley, J.K., Zarbin, M.A., Birdsall, N.J.M., and Kuhar, M.J. Muscarinic Cholinergic Receptor Localization by Radiohistochemistry.  In: Cholinergic Mechanisms, G. Pepeu and H. Ladinsky (Eds.).  Behav. Biol. 25.  Plenum Press, New York, pp. 587‑595, 1981.
  38. Kuhar, M.J. The Benzodiazepine Receptor: Anatomical Aspects. In: Benzodiazepines: A Review of Research Results, 1980, (NIDA Research Monograph Series 33), S.I. Szara and J.P. Ludford (Eds.). U.S. Government Printing Office, Washington, DC, pp. 12‑21, 1981.
  39. Young, W.S., III, and Kuhar, M.J. The Light Microscopic Radiohistochemistry of Drug and Neurotrans­mitter Receptors Using Diffusible Ligands.   In: Current Trends in Morphological Techniques, Vol. III, J.E. Johnson, Jr. (Ed.).  CRC Press, Boca Raton, FL, pp. 119‑135, 1981.
  40. Young, W.S., III, and Kuhar, M.J. Anatomical Mapping of Clonidine (Alpha‑2 Noradrenergic) Receptors in Rat Brain: Relationship to Function.  In: Psychopharmacology of Clonidine, H. Lal (Ed.).  Alan R. Liss, Inc., New York, pp. 41‑52, 1981.
  41. Kuhar, M.J. Localizing Drug and Neurotransmitter Receptors in vivo with Tritium‑Labeled Tracers.  In: Receptor‑Binding Radiotracers, Vol. 1, W.C. Eckelman (Ed.). CRC Press, Boca Raton, FL, pp. 37‑50, 1982.
  42. Kuhar, M.J. Localization of Drug and Neurotransmitter Receptors in Brain by Light Microscopic Auto­radiography.  In: The Handbook of Psychopharmacology, Vol. 15, S.D. Iversen, L.L. Iversen and S.H. Snyder (Eds.).  Plenum Publ. Co., New York, pp. 299‑320, 1982.
  43. Kuhar, M.J. Opioid Receptors and Peptides in Pain Control.  In: Diagnosis and Treatment of Chronic Pain, N.H. Hendler, D.M. Long and T.N. Wise (Eds.). Johns Wright Publishing, Inc., Boston, pp. 193‑199, 1982.
  44. Kuhar, M.J. Radiohistochemical Localization of Benzodiazepine Receptors.  In: Pharmacology of Benzo­diazepines, E. Usdin, P. Skolnick, J.F. Tallman, Jr., D. Greenblatt, and S.M. Paul (Eds.).  Macmillan Press, New York, pp. 149‑154, 1982.
  45. Pögün, S., Duelfer, T., Corley, E.G., Dannals, R.F., Dranbauer, B.J., Scheffel, U., Waud, J.M., O’Brien, H.A., Kuhar, M.J., Burns, H.D., and Wagner, H.N., Jr. Radiolabeled Spiperone Analogues for Imaging Dopamine Receptors.  In: Nuclear Medicine and Biology Advances. Proceedings of the Third World Congress of Nuclear Medicine and Biology, Vol. IV, C. Raynaud (Ed.).  Pergamon Press, Paris, pp. 3606‑3609, 1982.
  46. Kuhar, M.J., Wamsley, J.K., Palacios, J.M., Niehoff, D.L., Zarbin, M.A., and Unnerstall, J.R. Drug and Neurotransmitter Receptors: Anatomical Localization in the Brain.  In: Pharmacologic and Biochemical Aspects of Neurotransmitter Receptors, H. Yoshida and H.I. Yamamura (Eds.).  John Wiley and Sons, New York, pp. 161‑174, 1983.
  47. Kuhar, M.J. Autoradiographic Localization of Drug and Neurotransmitter Receptors.  In: Methods in Chemical Neuroanatomy; Vol. 1, Handbook of Chemical Neuroanatomy, A. Björklund and T. Hökfelt (Eds.). Elsevier, Amsterdam, pp. 398‑415, 1983.
  48. Kuhar, M.J. and Zarbin, M.A. Axonal Transport of Muscarinic Cholinergic Receptors and its Implications.  Trends Pharmacol. Sci.(Suppl.): 53‑54, 1984.
  49. Kuhar, M.J. Mapping Multiple Benzodiazepine Receptors in the CNS.  Roche Receptor 1: 1‑2, 1984.
  50. Zarbin, M.A. and Kuhar, M.J. Axonal Transport of Receptors.  IUPHAR 9th Int. Cong. Pharmacol. Proc. 1: 81‑84, 1984.
  51. Innis, R.B., Zarbin, M.A., Kuhar, M.J., and Snyder, S.H. Central and Peripheral CCK Receptors.   In: Brain Receptor Methodologies, Part B, P.J. Marangos, I.C. Campbell and R.M. Cohen (Eds.). Academic Press, New York, pp. 111‑127, 1984.
  52. Wagner, H.M., Jr., Burns, H.D., Dannals, R.F., Wong, D.F., Langstrom, B., Duelfer, T., Frost, J.J., Ravert, H.T., Links, J.M., Rosenbloom, S., Lukas, S.E., Kramer, A.V., and Kuhar, M.J. Assessment of Dopamine Receptor Activity in the Human Brain With Carbon‑11 N‑Methylspiperone.  In: Proceed­ings from the Third Symposium on the Medical Application of Cyclotrons, Turku, Finland, June 13‑16, 1983.  Univ. Turkvensis D 17: 263‑268, 1984.
  53. Wagner, H.N., Dannals, R.F., Frost, J.J., Wong, D.F., Ravert, H.T., Wilson, A.A., Links, J.M., Burns, H.D., Kuhar M.J., and Snyder, S.H. Imaging Neuroreceptors in the Human Brain in Health  and Disease.  Proceedings of an International Conference on Radio‑pharmaceuticals and Labelled Compounds, pp. 503‑512, 1984.
  54. Kuhar, M.J. and Unnerstall, J.R. Quantitative Receptor Mapping by Autoradiography:  Some Current Technical Problems.  Neurosci. 8: 49‑53, 1985.
  55. Kuhar, M.J. The Mismatch Problem in Receptor Mapping Studies. Trends Neurosci. 8(5): 190-191, 1985.
  56. Kuhar, M.J. Receptor Localization with the Microscope.  In: Neurotransmitter Receptor Binding, 2nd Edition, H.I. Yamamura, S.J. Enna, M.J. Kuhar (Eds.).  Raven Press, New York, pp. 153‑176, 1985.
  57. Wagner, H.N., Burns, H.D., Dannals, R.F., Wong, D.F., Langstrom, B., Duelfer, T., Frost, J.J., Ravert, H.T., Links, J.M., Rosenbloom, S., Lukas, S.E., Kramer, A.V., and Kuhar, M.J. In: The Metabolism of the Human Brain Studied with Positron Emission Tomography, T. Greitz et al. (Eds.).  Raven Press, New York, pp. 251‑267, 1985.
  58. Freed, W.J., Olson, L., Ko, G.N., Morihisa, J.M., Niehoff, D., Stromberg, I., Kuhar, M.J., Hoffer, B.J., and Wyatt, R.J. Intraventricular Substantia Nigra and Adrenal Medulla Grafts: Mechanisms of Action and [3H]Spiroperidol Autoradiography.  In: Neural Grafting in the Mammalian CNS, A. Bjorklund and U. Stenevi (Eds.).  Elsevier Science Publishers, New York, pp. 471‑489, 1985.
  59. Kuhar, M.J., Unnerstall, J.R., and De Souza, E.B. Receptor Mapping in Neuropharmacology by Auto­radiography: Some Technical Problems.  NIDA Research Monograph 62: 1‑12, 1985.
  60. Kuhar, M.J. Neuroanatomical Substrates of Anxiety: A Brief Survey. Trends Neurosci. 9: 307‑311, 1986.
  61. Kuhar, M.J., De Souza, E.B., and Unnerstall, J.R. Neurotransmitter Receptor Mapping by Autoradiography and Other Methods. Rev. Neurosci. 9: 27‑59, 1986.
  62. Whitehouse, P.J., Loats, H.L., Price, D.L., Lloyd, D.G., Kuhar, M.J., and Altschuler, R.J. New Approaches in Quantitative Neuropathology.  In: Biological Psychiatry, C. Shagass et al. (Eds.). Elsevier Science Publishing Co., New York, pp. 1385‑1387, 1986.
  63. De Souza, E.B. and Kuhar, M.J. Corticotropin‑Releasing Factor Receptors in the Pituitary Gland and Central Nervous System: Methods and Overview.  In: Methods in Enzymology, Vol. 124, P.M. Conn (Ed.).  Academic Press, New York, pp. 560‑590, 1986.
  64. Wagner, H.N., Jr., Dannals, R.F., Frost, J.J., Wong, D.F., Ravert, H.T., Wilson, A.A., Links, J.M., Burns, H.D., Kuhar, M.J., and Snyder, S.H. Imaging Dopamine and Opiate Receptors in the Human Brain in Health and Disease.  In: Biomedical Imaging, O. Hayaishi (Ed.).  Academic Press, New York, pp. 285‑296, 1986.
  65. Kuhar, M.J. Quantitative Receptor Autoradiography: An Overview.  In: Quantitative Receptor Autoradiog­raphy, C.A. Boast, E.W. Snowhill and C. A. Altar (Eds.).  Alan R. Liss, Inc., New York, pp. 1‑12, 1986.
  66. Kuhar, M.J. Recent Progress in Receptor Mapping: Which Neurons Contain the Receptors?  Trends Neurosci. 10: 308‑310, 1987.
  67. Kuhar MJ. Imaging receptors for drugs in neural tissue. 1987 Jul;26(7B):911-6. Review. PMID:2821433
  68. Kuhar, M.J. and Goeders, N.E. Receptor Mapping in Psychopharmacology.  In: Psychopharmacology: The Third Generation of Progress, H.Y. Meltzer (Ed.).  Raven Press, New York, pp. 313‑316, 1987.
  69. Kuhar, M.J. Human Brain Mapping.  In: Molecular Biology of the Human Brain, E.G. Jones (Ed.). Alan R. Liss, New York, pp. 185-190, 1988.
  70. Wagner, H.N., Jr., Weinberger, D.R., Kleinman, J.E., Casanova, M.F., Gibbs, C.J., Jr., Gur, R.E., Hornykiewicz, O., Kuhar, M.J., Pettegrew, J.W., and Seeman, P. Neuroimaging and Neuropathology. Schizophr. Bull. 14(3): 383‑397, 1988.
  71. Ritz, M.C., Lamb, R.J., Goldberg, S.R., and Kuhar, M.J. Cocaine Self‑administration Appears to be Mediated by Dopamine Uptake Inhibition.  Neuro‑Psychopharmacol. Biol. Psychiat. 12: 233‑239, 1988.
  72. Unnerstall, J.R. and Kuhar, M.J. Mapping the Alpha Adrenergic Receptor in the Central Nervous System: A Guide to Structure and Function.  In: Epinephrine in the Central Nervous System, J.M. Stolk, D.C. U’Prichard and K. Fuxe (Eds.).  Oxford University Press, New York, pp. 45‑58, 1988.
  73. Kuhar, M.J.   In: Receptor Localization: Ligand Autoradiography, F.M. Leslie and C.A. Altar (Eds.).  Alan R. Liss, New York, pp. 1‑7, 1988.
  74. Kuhar, M.J., Ritz., M.C., and Sharkey, J. Cocaine Receptors on Dopamine Transporters Mediate Cocaine-Reinforced Behavior.  In: Mechanisms of Cocaine Abuse and Toxicity (NIDA Research Monograph Series 88), D. Clouet, K. Asglan and R. Brown (Eds.).  S. Government Printing Office, Washington, DC, pp. 14‑22, 1988.
  75. Wong, D.F. and Kuhar, M.J. In vivo PET and SPECT Receptor Imaging: New Technology and Tactics for Receptor Measurement.  In: Neuroreceptors and Signal Transduction, S. Kito, T. Segawa, K. Kuriyama, M. Tohyama and R.W. Olsen (Eds.).  Plenum Press, New York, pp. 181‑193, 1988.
  76. Wagner, H.N., Weinberger, D.R., Kleinman, J.E., Casanova, M.F., Gibbs, C.J., Gur, R.E., Hornykiewicz, O., Kuhar, M.J., Pettegrew, J.W., and Seeman, P. Scientific Directions: A Plan for Research on Schizo­phrenia.  Neuroimaging and Neuropathology Panel.  A National Plan for Schizo­phrenia Research:  Report of the National Advisory Mental Health Council.  DHHS Publication No. (ADM) 88‑1571, pp. 19‑22, 1988.
  77. Wagner, H.N., Weinberger, D.R., Kleinman, J.E., Casanova, M.F., Gibbs, C.J., Gur, R.E., Hornykiewicz, O., Kuhar, M.J., Pettegrew, J.W., and Seeman, P. A National Plan for Schizophrenia Research: Panel Recommendations.  Neuroimaging and Neuropathology Panel.  DHHS Publication No. (ADM) 88‑1570, pp. 39‑53, 1988.
  78. Kuhar, M.J. and De Souza, E.B. Autoradiographic Imaging: Localization of Binding Sites Other Than Neurotransmitter Receptors.  In: Visualizations of Brain Functions, D. Ottoson and W. Rostene (Eds.). Stockton Press, New York, pp. 57‑66, 1989.
  79. Ritz MC, Boja JW, George FR, Kuhar MJ. Cocaine binding sites related to drug self-administration. NIDA Res Monogr. 1989;95:239-46. Review. PMID:2561828
  80. Kuhar, M.J.   In: Brain Imaging Techniques and Applications, N.A. Sharif and M.E. Lewis (Eds.).  John Wiley & Sons, New York, pp. 13‑17, 1989.
  81. Kuhar, M.J. Cocaine Receptors and Dopamine Transporters.  Facts 1(3): 3, 1990.
  82. Kuhar, M.J. A GABA Transporter cDNA has been Cloned.  Trends Neurosci. 13: 473-474, 1990.
  83. Kuhar, M.J. and Unnerstall, J.R. Receptor Autoradiography.  In: Methods in Neurotransmitter Receptor Analysis, H.I. Yamamura, S.J. Enna, and M.J. Kuhar (Eds.).  Raven Press, New York, pp. 177‑218, 1990.
  84. Kuhar, M.J. Introduction to Neurotransmitters and Neuroreceptors.  In: Quantitative Imaging: Neuro­receptors, Neurotransmitters, and Enzymes, J.J. Frost and H.W. Wagner, Jr. (Eds.).  Raven Press, New York, pp. 1‑7, 1990.
  85. Kuhar, M.J., Ritz, M.C., and Boja, J.W. The Dopamine Hypothesis of the Reinforcing Properties of Cocaine.  Trends Neurosci. 14(7): 299-302, 1991.
  86. Carroll, F.I., Rahman, M.A., Philip, A., Lewin, A.H., Boja, J.W., and Kuhar, M.J. Synthesis and Receptor Binding of Cocaine Analogs.  In: Problems of Drug Dependence 1990: Proceeding of the 52nd Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. (NIDA Research Monograph Series 105), L.S. Harris (Ed.).  S. Government Printing Office, Washington, DC, pp. 147‑153, 1991.
  87. Kuhar, M.J. Perspectives on Receptor Autoradiography in Human Brain.  In: Receptors in the Human Nervous System, F.A.O. Mendelsohn and G. Paxinos (Eds).  Academic Press, San Diego, pp. 1‑8, 1991.
  88. Simantov, R., Vaughan, R., Lew, R., Wilson, A., and Kuhar, M.J. Dopamine Transporter – Cocaine Receptor: Characterization and Purification.  Biosci. 82: 151-154, 1991.
  89. Kuhar, M.J., Ritz, M.C., Grigoriadis, D., Lew, R., and Sharkey, J. A Cocaine Receptor Associated with Dopamine Transport and Drug Self-administration.  In: Cocaine Pharmacology, Physiology and Clinical Strategies, J.M. Lakoski, M.P. Galloway and F.J. White (Eds.). CRC Press, Boca Raton, pp. 191-202, 1992.
  90. Ritz, M.C., Kuhar, M.J., and George, F.R. Molecular Mechanisms Associated with Cocaine Effects: Pos­sible Relationships with Effects of Ethanol.  In: Recent Developments in Alcoholism, Vol. 10, Alcohol and Cocaine: Similarities and Differences, M. Galanter (Ed.).  Plenum Press, pp. 273-302, 1992.
  91. Kuhar, M.J. Molecular Pharmacology of Cocaine: A Dopamine Hypothesis and Its Implications.  In: 1992 Cocaine: Scientific and Social Dimensions.  Ciba Foundation Symposium 166, pp. 81-95, 1992.
  92. Kuhar, M.J. Neurotransmitter Transporters: An Overview. In: Neuroscience Facts, Vol. 3(13), D.L. Cheney, K.W. Brocklehurst, and L. Winegarner (Eds.).  Fidia Research Foundation, Washington, DC, p. 49, 1992.
  93. Boja, J.W., Cline, E.J., Carroll, F.I., Lewin, A.H., Philip, A., Dannals, R., Wong, D., Scheffel, U., and Kuhar, M.J. High Potency Cocaine Analogs: Neurochemical, Imaging, and Behavioral Studies.  N.Y. Acad. Sci. 654: 282-291, 1992.
  94. Amara, S.G. and Kuhar, M.J. Neurotransmitter Transporters: Recent Progress.  Rev. Neurosci. 16: 73-93, 1993.
  95. Ritz, M.C. and Kuhar, M.J. Psychostimulant Drugs and a Dopamine Hypothesis Regarding Addiction: Update on Recent Research.  Soc. Symp. 59: 51-64, 1993.
  96. Kuhar, M.J. The Otto Krayer Award Lecture: Neurotransmitter Transporters as Drug Targets: Recent Research with a Focus on the Dopamine Transporter.  The Pharmacologist 35(1): 28-33, 1993.
  97. Kuhar, M.J. and DeSouza, E.B. Receptor Autoradiography as an Aid in Explaining Drug Action.  In: Imaging Drug Action in the Brain, E.D. London (Ed.).  CRC Press, Boca Raton, pp. 49-60, 1993.
  98. Adler, M.W., Dingell, J.V. Harris, L.S., and Kuhar, M.J. Conference Summary:  Drug Addiction — A Chronic Treatable Disease.  In:  Biomedical Approaches to Illicit Drug Demand Reduction, C.R. Hartel (Ed.).  National Institutes on Drug Abuse, NIH Publication No. 93-3698, p. 269, 1993.
  99. Carroll FI, Lewin AH, Kuhar MJ, Boja JW. Cocaine receptor: a structure-activity relationship study. NIDA Res Monogr. 1993;134:229-37. Review. PMID:8289880
  100. Carroll, F.I., Lewin A.H., Boja, J.W., and Kuhar, M.J. 3_-(Substituted Phenyl) Tropan-2-Carboxylic Acid Ester Analogues of Cocaine. In: Drug Design for Neuroscience, Alan P. Kozikowski (Ed.).  Raven Press, New York, pp. 149-166, 1993.
  101. Boja, J.W., Vaughan, R., Patel, A., Shaya, E.K., and Kuhar, M.J. The Dopamine Transporter. In: Dopamine Receptors and Transporters, H.B. Niznik (Ed.).  Marcel Dekker, New York, pp. 611-644, 1994.
  102. Pögün, S. and Kuhar, M.J. Regulation of Neurotransmitter Reuptake by Nitric Oxide. N.Y. Acad. Sci. 738: 305-315, 1994.
  103. Scheffel, U., Dannals, R.F., Suehiro, M., Ricaurte, G.A., Carroll, F.I., Kuhar, M.J., and Wagner, H.N., Jr. Development of PET/SPECT Ligands for the Serotonin Transporter. NIDA Res. Monogr. 138: 111-130, 1994.
  104. Carroll, F.I., Schewffel, U., Dannals, R.F., Boja, J.W., and Kuhar, M.J. Development of Imaging Agents for the Dopamine Transporter. Res. Rev., 15: 419-444, 1995.
  105. Kuhar, M.J. In: Sites of Drug Action in the Human Brain, A. Beigon and N.D. Volkow (Eds.). CRC Press, Boca Raton, pp. 173-178, 1995.
  106. Kuhar, M.J. In vitro Labeling Autoradiography: Development and Perspectives. In: Auto­radiography and Correlative Imaging, W.E. Stumpf and H.F. Solomon (Eds.).  Academic Press, San Diego, pp. 203-219, 1995.
  107. Zarbin, M.A., Unnerstall, J.R., and Kuhar, M.J. Axonal Transport of Receptors: Emphasis on a2-Adrenic Binding Sites. In: Autoradiography and Correlative Imaging, W.E. Stumpf and H.F. Solomon (Eds.).  Academic Press, San Diego, pp. 309-320, 1995.
  108. Kuhar, M.J., Boja, J.W., Patel, A., Pilotte, N., Cerruti, C., and Lever, J. Cocaine and Dopamine Transporters. In: The Neurobiology of Cocaine: Cellular and Molecular Mechanisms, R.P. Hammer, Jr. (Ed.). CRC Press, Boca Raton, pp. 201-213, 1995.
  109. Kuhar, M.J. and Pilotte, N.S. Review: Neurochemical Changes in Cocaine Withdrawal. TiPS 17: 260-264, 1996.
  110. Kuhar, M.J. and Schuster, C.R. Integrative Neurobehavioral Pharmacology: Focus on Cocaine. In:  Pharmacological Aspects of Drug Dependence: Toward an Integrated Neurobehavioral Approach, Vol. 118, Handbook of Experimental Pharmacology, C.R. Schuster and M.J. Kuhar (Eds.).  Springer-Verlag, New York, pp. 53-80, 1996.
  111. Carroll, F.I., Lewin, A.H. and Kuhar, M.J. Chapter 9: Dopamine Transporter Uptake Blockers. In: Neurotransmitter Transporters: Structure, Function and Regulation, M.E.A. Reith (Ed.).  Humana Press, Clifton, NJ, pp. 263-295, 1997.
  112. Kuhar, M.J., Carroll, F.I., Lewin, A.H., Boja, J.W., Scheffel, U., and Wong, D.F. Imaging Trans­porters for Dopamine and Other Neurotransmitters in Brain. In: Neurotransmitter Trans­porter: Struc­ture, Function, and Regulation, M.E.A. Reith (Ed.).  Humana Press, Clifton, NJ, pp. 297-313, 1997.
  113. Kuhar, M.J. Dopamine Transporter: Function and Imaging. In: Neurotransmitter Release and Uptake, S. Pögün (Ed.).  Springer-Verlag, Berlin/Heidelberg, pp. 221-229, 1997.
  114. Patel, A.P., Carroll, F.I., and Kuhar, M.J. Turnover of Rat Dopamine Transporter Protein in rDAT-LLC-PK1 Cells. In:  Neurotransmitter Release and Uptake, S. Pögün (Ed.).  Springer-Verlag, Berlin/ Heidelberg, pp. 231-236, 1997.
  115. Kuhar, M.J. Basic Neurobiological Research: 1989-1991. In:  Drug Abuse and Drug Abuse Research, the Fourth Triennial Report to Congress from the Secretary, Department of Health and Human Services.  National Institutes of Health, pp. 4.1-4.8, 1997.
  116. Kuhar, M.J. Developing Medications for Drug Abusers. In: Harnessing Technology to Support the National Drug Control Strategy.  Proceedings of the 1997 Office of National Drug Control Policy [ONDCP] Interna­tional Technology Symposium, Chicago, Illinois, August 18-21, pp. 2-3 – 2-4, 1997.
  117. Kuhar, M.J. Recent Biochemical Studies of the Dopamine Transporter – A CNS Drug Target. Life Sci. 62(17/18): 1573-1575, 1998.
  118. Kuhar, M.J. Review: Cocaine Addiction: Theory, Research and Treatment, by J.J. Platt, Harvard University Press, 1997.  Trends Neurosci. 21(6): 270, 1998.
  119. Kuhar, M.J., Vaughan, R., Uhl, G., Cerruti, C., Revay, R., Freed, C., Nirenburg, M., and Pickel, V. Locali­zation of Dopamine Transporter Protein by Microscopic Histochemistry. Pharma­col. 42: 168-170, 1998.
  120. Kuhar, M.J., Vaughan, R., Uhl, G., Cerruti, C., Revay, R., Freed, C., Nirenburg, M., and Pickel, V. Localization of Dopamine Transporter Protein by Microscopic Histochemistry. In: Catecholamines: Bridging Basic Science with Clinical Medicine, D.S. Goldstein, G. Eisenhofer, and R. McCarty (Eds.). Academic Press, San Diego, pp. 168-170, 1998.
  121. Wong, D.F., Ricaurte, G., Gründer, G., Rothman, R., Naidu, S., Singer, H., Harris, J., Yokoi, F., Villemagne, V., Szymanski, S., Gjedde, A., and Kuhar, M. Dopamine Transporter Changes in Neuropsychiatric Disorders. In: Catecholamines: Bridging Basic Science with Clinical Medicine, D.S. Goldstein, G. Eisenhofer, and R. McCarty (Eds.).  Academic Press, San Diego, pp. 219-222, 1998.
  122. Vaughan, R.A., Huff, R.A., Uhl, G.R., and Kuhar, M.J. Phosphorylation of Dopamine Transporters and Rapid Adaptation to Cocaine. In: Catecholamines: Bridging Basic Science with Clinical Medicine, D.S. Goldstein, G. Eisenhofer, and R. McCarty (Eds.).  Academic Press, San Diego, pp. 1042-, 1998.
  123. Kuhar, M.J., Couceyro, P.R., and Lambert, P.D. In: Basic Neurochemistry: Molecular, Cellular and Medical Aspects, 6th Edition, G.J. Siegel (Editor-in-Chief), B.W. Agranoff, R.W. Albers, S.K. Fisher, and M.D. Uhler (Eds.). Lippincott-Raven Publ., Philadelphia/New York, pp. 243-261, 1998.
  124. Kuhar, M.J. and Dall Vechia, S.E. CART Peptides: Novel Addiction- and Feeding-Related Neuropeptides. Trends Neurosci. 22: 316-320, 1999.
  125. Carroll, F.I., Howell, L.L., and Kuhar, M.J. Pharmacotherapies for Treatment of Cocaine Abuse: Preclinical Aspects. Med. Chem. 42: 2721-2736, 1999.
  126. Adams, L.D., Gong, W., Dall Vechia, S., Hunter, R.G., and Kuhar, M.J. CART: From Gene to Function. Brain Res. 848: 137-140, 1999.
  127. Kuhar, M.J. In: The Dana Brain Science Guide: Resources of Secondary and Post-Secondary Teachers and Students.  The Dana Press, New York, pp. 47-48, 1999.
  128. Mandel, A.J., Selz K.A., Shlesinger, M.F., and Kuhar, M.J. Linear and Entropic Transformations of the Hydrophobic Free Energy Sequence Help Characterize a Novel Brain Polyprotein: CART’s Protein.  In: Statistical Physics on the Eve of the 21st Century, M.T. Batchelor and L.T. Wille (Eds.).  World Scientific: Singapore, pp. 131-152, 1999.
  129. Kuhar, M.J., Adams, L.D., Hunter, R.G., Dall Vechia, S., and Smith, Y. Invited Review: CART Peptides. Regulatory Peptides 89: 1-6, 2000.
  130. Kuhar MJ. In vitro autoradiography. Curr Protoc Pharmacol. 2001 May;Chapter 8:Unit 8.1. doi: .1002/0471141755.ph0801s00. PMID:21971813
  131. Kuhar MJ, Joyce A, Dominguez G. Genes in drug abuse. Drug Alcohol Depend. 2001 May 1;62(3):157-62. Review. PMID:11295319
  132. Dallvechia-Adams, S., and Kuhar, M.J. CART (CART Peptides). In: Wiley Encyclopedia of Molecular Medicine.  John Wiley & Sons, New York, pp. 479-481, 2002.
  133. Kuhar, M.J. Social Rank and Vulnerability to Drug Abuse. Nature Neurosci. 2: 88-90, 2002.
  134. Kuhar, M.J., Adams, S., Dominguez, G., Jaworski, J., and Balkan, B. CART Peptides. Neuropeptides 36: 1-8, 2002.
  135. Kuhar, M.J. and Pogun, S. Neuropsychopharmacology 28: 51, 2003.
  136. de Wit, H., Haney, M., Kosten, T.R., Walsh, S.L., and Kuhar, M.J. Dopamine Antagonists and Responses to Stimulant Drugs in Humans. Symposium VI. Drug Reward in Humans: What Does Dopamine Do? (H. de Wit, Chair). NIDA Research Mono­graph Series No. 183. Problems of Drug Dependence 2002: Proceedings of the 64th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc., p. 50, 2003.
  137. Kuhar, M.J. Symposium VI. Drug Reward in Humans: What Does Dopamine Do? (H. de Wit, Chair). NIDA Research Mono­graph Series No. 183. Problems of Drug Dependence 2002: Proceedings of the 64th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc., pp. 57-58, 2003.
  138. Hunter, R.G. and Kuhar, M.J. CART Peptides as Targets for CNS Drug Development. Drug Targets: CNS Neurol. Disord. 2: 201-205, 2003.
  139. Jaworski, J.N., Vicentic, A., Hunter, R.G., Kimmel, H.L., and Kuhar, M.J. CART Peptides are Modulators of Mesolimbic Dopamine and Psychostimulants. Life Sci. 73: 741-747, 2003.
  140. Kuhar, M.J. Views of The College on Problems of Drug Dependence Regarding Advances in Reseasrch on Drug Abuse. In: Neuroscience of Psychoactive Substance Use and Dependence. World Health Organization, Geneva, ISBN #92 4156235 8, 2004.
  141. Kuhar, M.J. (Chair). Symposium XII. Changing Proteins, Changing Brains. NIDA Research Monograph Series No. 184. Problems of Drug Dependence 2003: Proceedings of the 65th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc., W.L. Dewey (Ed), 88-92, 2004.
  142. Kuhar, J.M. The Politics of Advice: Biased Scientific Information in Government Agencies. The Academic Exchange 7(1): 10-11, 2004.
  143. Hunter, R.G., Philpot, K., Vicentic, A., Dominguez, G., Hubert, G.W., and Kuhar, M.J. CART in Feeding and Obesity. Trends Endocrinol. Metab. 15: 454-459, 2004.
  144. Dominguez, G., Vicentic, A., del Giudice, E.M., Jaworski, J., Hunter, R.G., and Kuhar, M.J. CART Peptides: Modulators of Mesolimbic Dopamine, Feeding, and Stress. Ann. N.Y. Acad. Sci. 1025: 363-369, 2004.
  145. Kuhar, M.J. Addiction: It’s in the Genes. Letters to the Editor re “Some Gene Research Isn’t Worth the Money” (Jan. 18). The New York Times, New York, Jan. 25, 2005.
  146. Kuhar, M.J., Jaworski, J.N., Hubert, G.W., Philip, K.B., and Dominguez, G. Cocaine- and Amphetamine-Regulated Transcript Peptides Play a Role in Drug Abuse and are Potential Therapeutic Targets. AAPS 7: E259-E265, 2005.
  147. Kuhar, M.J., Minneman, K., and Muly, E.C. Catecholamines. In: Basic Neurochemistry: Molecular, Celluar, and Medical Aspects, 7th Edition, G.J. Siegel, R.W. Albers, S.T. Brady and D.L. Price (Eds.). Elsevier Academic Press: Burlington, MA, pp. 211-225, 2006.
  148. Carroll, F.I., Howard, J.L., Howell, L.L., Fox, B.S., and Kuhar, M.J. Development of the Dopamine Transporter Selective RTI-336 as a Pharmacotherapy for Cocaine Abuse. AAPS J. 8: E196-E203, 2006.
  149. Kuhar, M.J. Introductory Note. Peptides 27: 1911-1912, 2006.
  150. Koylu, E. O., Balkan, B., Kuhar, M.J., and Pogun, S. Cocaine and Amphetamine Regulated Transcript (CART) and the Stress Response. Peptides 27: 1956-1569, 2006.
  151. Kuhar, M.J. Should Codes of Ethics Include Expectations of Others? (Letter to the Editor).  Eng. Ethics 12: 413-414, 2006.
  152. Philpot, K.B. and Kuhar, M.J. CART Peptide and Ingestive Behavior. In: Handbook of Biologically Active Peptides, A.J. Kastin (Ed.). Elsevier Academic Press: Burlington, MA, pp. 913-918, 2006.
  153. Damaj, M.K., Zheng, J., Martin, B.R., and Kuhar, M.J. Intrathecal CART (55-102) Attenuates Hyperlagesia and Allodynia in a Mouse Model of Neuropathic but not Inflammatory Pain. Peptides 27: 2019-2023, 2006.
  154. Moffett, M.C., Vicentic, A., Kozel, M., Plotsky, P., Francis, D.D., and Kuhar, M.J. Maternal Separation Alters Drug Intake Patterns in Adulthood in Rats.  Pharmacol. 73: 321-330, 2007.
  155. Kuhar, M.J. Why Just Saying No Is Not Enough.  In: 2007 Advances in Brain Research, B. Rich (Ed.). Dana Foundation Press, pp. 11-12, 2007.
  156. Kuhar, M.J. Introduction of the Nathan B. Eddy Recipient.  NIDA Research Monograph Series No. 187.  Problems of Drug Dependence, 2006: Proceedings of the 68th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc., pp 69-70, 2007.
  157. Kuhar, M. J. Creative Minds and the Greatness Game – A Response. The Academic Exchange (Emory), 10: 10-11, 2007.
  158. Hubert GW, Jones DC, Moffett MC, Rogge G, Kuhar MJ. CART peptides as modulators of dopamine and psychostimulants and interactions with the mesolimbic dopaminergic system.  Biochem Pharmacol. 2008 Jan 1;75(1):57-62. Epub 2007 Jul 26.  PMID 17854774.
  159. Kuhar, MJ, Jaworski JN, Hubert GW, Philpot KB, and Dominguez G. Cocaine-and Amphetamine Regulated transcript peptides play a role in drug abuse and are potential therapeutic targets.  In: Drug Addiction: from basic research to therapy, Rapaka RS and Sadee W (Eds).  Springer, pp 101-112, 2008.
  160. Carroll FI, Howard, JL, Howell LL, Fox BS, Kuhar MJ.  Development of the Dopamine Transporter selective RTI-336 as a Pharmacotherapy for cocaine abuse.  In: Drug Addiction: from basic research to therapy, Rapaka RS and Sadee W (Eds).  Springer, pp 1179-192, 2008.
  161. Rogge, G., Jones, D., Hubert, G.W., Lin, Y and Kuhar, MJ. CART peptides: regulators of body weight, reward and other functions.  Nat Rev Neurosci, 9(10):747-58. 2008.  PMID: 18802445. PMCID: PMC4418456.
  162. Kuhar, M.J. On Blacklisting in Science.  Sci Eng Ethics 14:301-303, 2008.  PMID 18668347
  163. Kuhar, M.J. Blacklisting Whistleblowers. ORI Newsletter, 17(1): 6, Dec 2008.
  164. Kuhar M.J. Blacklisting Among Scientists.  Synapse 63:539-540, 2009.  PMID 19253401.
  165. Kuhar M.J. On the Use of Protein Turnover and Half-lives.  Neuropsychopharmacol  34(5):1172-3, 2009.           PMID 18923400.
  166. Kuhar, M.J. Measuring levels of proteins by various technologies: can we learn more by measuring turnover?         Biochem Pharmacol.  Mar 1; 79(5):665-668.    PMID: 19814998
  167. Kuhar, M.J. Contributions of basic science to understanding addiction.  Biosocieties 5:25-35, 2010.
  168. Kuhar , J.  Conversation with Michael Kuhar.  Addiction (Mar 10, 2010) 105:593-600, 2010.
  169. Frugoli, J., Etgen A.AM., and Kuhar, M. J. Developing and Communicating Responsible DATA Management Policies to Trainees and Colleagues.  Sci Eng Ethics 16(4):753-762, 2010.  PMID:20585892.
  170. Fuentealba, J.A., Gysling, K., and Kuhar, M. J., Avances en Neurociencias y Prevencion.  In: Hasta Cuando      Hablamos de Drogas, Maartinez, D., et al., Eds., Ediciones UC pp 32-53, 2010.
  171. Ali SF, Onaivi ES, Dodd PR, Cadet JL, Schenk S, Kuhar MJ, Koob GF. Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists.  Curr Neuropharmacol.  Mar;9(1):2-7.  2011 PMID: 21886551.
  172. Job MO, McNamara IM, Kuhar MJ. CART Peptides Regulate Psychostimulants and May be Endogenous Curr Neuropharmacol. 2011 Mar;9(1):12-6. PMID: 21886553
  173. Kuhar,   Collegial Ethics: What, why and how.  Drug and Alcohol Dependence. 119:235-238. 2011.
  174. Kuhar, MJ. Dr Kuhar Shares his life lessons. Accessed on May 22, 2013, taped on Dec 8, 2011. http://www.blogtalkradio.com/lifelessonsnetwork/2011/12/08/dr-michael-kuhar-shares-his-life-lessons
  175. Kuhar, MJ. Website for Collegial Ethics.  collegialethics.com. March, 2012.
  176. Kuhar MJ, Cross D. Collegial Ethics: Supporting Our Colleagues. Sci Eng Ethics. 19(3):677-684, 2013 PMID: 22535576
  177. Kuhar, MJ. Interview with askimo TV in Israel. Feb 20, 2013. Accessed on 4/29/13.  View: Video 1 / Video 2 / Video 3 / Video 4 / Video 5
  178. Shira Goldberg and MJ Kuhar, The Addiction Show. 12/16/2013. http://www.youtube.com/the1addictionshow.
  179. Kuhar, MJ. The Art and Ethics of Being a Good Colleague. FT Press, Upper Saddle River NJ, 2013.
  180. Harm Reduction radio. Jan 9, 2014. http://www.blogtalkradio.com/harm-reduction/2014/01/10/the-addicted-brain-why-we-abuse-drugs-alcohol-and-nicotine.
  181. Interview on WOCM-FM radio, Jan 16, 2014. Topic: collegial ethics.
  182. Interview on Huffington Post , Jan 21 2014, topic: collegial ethics.
  183. Kuhar, MJ. Getting Collegial. Emory Magazine, 90:16 Spring, 2014.
  184. Kuhar, MJ. Interview by Gwen Cardin on “Break the Chains” an internet show about addiction on June 5, 2014.:  https://www.dropbox.com/s/kp8na14ymsa6zrm/BTC%2006-05-14%20Drugs%20and%20the%20Brain.mp3
  185. Kuhar, MJ. The Addicted Brain. A MOOC by Coursera and Emory University.  Given on June 23, 2014. https://www.coursera.org/course/addictedbrain, accessed on July 31, 2014.
  186. Kuhar MJ. Interview with Elia Kabanov on the brain and drugs. http://en.metkere.com/2014/08/michaelkuhar.html,
  187. http://metkere.com/2014/08/michaelkuhar.html.  Accessed on August 15, 2014
  188. Kuhar MJ. 2014. Irreproducible Results. J Drug Alc Res, Vol 3. doi:10.4303/jdar/235879. http://www.ashdin.com/journals/JDAR/235879/, accessed on Sept 5, 2014.
  189. Kuhar MJ. Human nature: savior, nemesis or both? http://www.internationalinnovation.com/human-nature-saviour-nemesis-or-both/, accessed on feb 26, 2015.
  190. Kuhar, MJ. Can Sugar be Addicting? http://www.theneuroethicsblog.com/. Accessed on April 28, 2015.
  191. Kuhar MJ. Interviewed in “Neuroscience of Addiction”, by Centre Communications, accessed on 11/3/2015.  Listen: Part 1 / Part 2 / Part 3 / Part 4 / Part 5

 

ABSTRACTS

  1. Kuhar, M. J. and S. H.    Localization of 3H Glutamic Acid (3H GLU) and (3H GLY) in Synapto¬somes of Rat Cerebral Cortex.  Fed.  Proc.  28, 578, 1969.
  2. Kuhar, M. J. , S. H. Snyder and J. K.    Separation of Synaptosomes Containing Gamma-Amino¬butyric Acid (GABA), Serotonin (5 HT), Norepinephrine (NE) and Acetylcholine (Ach) in Mammalian Brain.  Fed.  Proc.  29, 1383, 1970.
  3. Kuhar, M. J. , K. M. Taylor, A. R.  Wofsey and S. H.    Separation of Amine and Amino Acid-Containing Synaptosomes from Rat Brain.  Pharmacologist 12, 256, 1970.
  4. Kuhar, M. J. , R. H. Roth and G. K.    A Selective Reduction of Tryptophan Hydroxylase Activity and Serotonin Levels in Forebrains from Rats with Midbrain Raphe Lesions.  Pharmacologist 13, 266, 1971.
  5. Kuhar, M. J. , R. H. Roth and G. K.    Choline Uptake into Synaptosomes from the Hippocampus: Reduction after Electrolytic Destruction of the Medial Septal Nucleus.  Fed.  Proc.  31, 516, 1972.
  6. Sethy, V. H. , R. H. Roth, M. J.  Kuhar and M. H.  Van Woert.  Regional Distribution and Effect of Degeneration of Cholinergic Nerve Terminals on Content of Acetylcholine and Choline in Rat Brain.    Amer.  Soc.  Neurochem.  4, 130, 1973.
  7. Rommelspacher, H. and M. J.    Effect of Lesions on the Action of Hemicholinium 3 (HC 3) on Acetylcholine and Choline in Rat Brain.  Trans.  Amer.  Soc.  Neurochem.  4, 130, 1973.
  8. Yamamura, H. I. , M. J. Kuhar and S. H.    Muscarinic Cholinergic Receptor Binding in Mammalian Central and Peripheral Nervous System: Demonstration in vitro and in vivo.  Trans.  Amer.  Soc.  Neurochem.  5, 72, 1974.
  9. Yamamura, H. I. , M. J. Kuhar and S. H.    Identification in vivo of Muscarinic Cholinergic Receptor Binding in Rat Brain.  Pharmacologist 16, 311, 1974.
  10. Simon, J. R. and M. J.    Inhibition of Choline Uptake into Synaptosomes by Choline Analogues.  Pharmacologist 16, 286, 1974.
  11. Kuhar, M. J. and H. I.    Light Autoradiographic Localization of Cholinergic Muscarinic Sites in Rat Brain.  Soc.  Neurosci.  Abstr.  4, 294, 1974.
  12. Rommelspacher, H. and M. J.    Acetylcholine Levels after Electrical Stimulation of the Cholinergic Septal Hippocampal Pathway.  Soc.  Neurosci.  Abstr.  4, 399, 1974.
  13. Simon, J. R. and M. J.    Attempts at Identifying the Glutamate Receptor in Brain Tissue by Binding Radiolabeled Kainic Acid.  Fed.  Proc.  34, 294, 1975.
  14. Simon, J. R. and M. J.    Sodium Dependent High Affinity Choline Uptake as a Regulatory Step in Acetylcholine Synthesis.  The Pharmacologist 17, 255, 1975.
  15. Atweh, S. and M. J.    Effects of Impulse Flow Alterations on the in vivo Synthesis of 3H Acetyl¬choline in the Rat Hippocampus.  The Pharmacologist 17, 255, 1975.
  16. Rommelspacher, H. and M. J.    The Effect of Cholinergic Drugs on the Acetylcholine Concentration of the Hippocampus of Rats.  Proc.  6th Internat.  Cong.  Pharmacol. , pp.  99, 1975.
  17. Snyder, S. H. , G. W. Pasternak, I.  Creese, D. B.  Pert and M. J.    The Opiate Receptor seems Designed for a “Pain” Neurotransmitter.  5th Annual Meeting of the International Society for Neurochemistry, pp.  52 57, 1975.
  18. Simon, J. R. , S. Atweh and M. J.    Regulation of Acetylcholine Synthesis by Sodium Dependent High Affinity Choline Uptake.  Neurosci.  Abstr.  1, 381, 1975.
  19. Murrin, L. C. and M. J.    In vitro Activation of High Affinity Choline Uptake by Depolarization.  American Society for Neurochemistry.  Seventh Annual Meeting, p.  113, 1976.
  20. Kuhar, M. J. Autoradiographic Localization of Receptor Sites in the CNS in vivo.  Collegium Internationale Neuro Psychopharmacologicum, 10th Congress, p.  13, 1976.
  21. Kuhar, M. J. Sodium Dependent High Affinity Choline Uptake: A Regulatory Step in the Synthesis of Acetylcholine, and a Relative Measure of Neuronal Activity.  Collegium Internationale Neuro Psychopharmacologicum, 10th Congress, p.  131, 1976.
  22. Atweh, S. F. and M. J.    Autoradiographic Localization of Opiate Receptors in Spinal Cord and Lower Medulla of the Rat.  Neurosci.  Abstr.  2 , 564, 1976.
  23. Bird, S. J. and M. J.    The Action of Opiates at Autoradiographically Identified Opiate Receptor Sites: A Microiotophoretic Study.  Fed.  Proc.  35, 310, 1976.
  24. Kuhar, M. J. , S. F. Atweh, L. C.  Murrin, R.  Simantov and S. H.    Cellular Localization of the Opiate Receptor and Enkephalin.  Trans.  Am.  Soc.  Neurochem.  8, 61, 1977.
  25. Murrin, L. C. , R. N. DeHaven, N.  Tulipan, M. A.  Zarbin and M. J.    Acetylcholine Release and High Affinity Choline Uptake.  Trans.  Am.  Soc.  Neurochem.  8, 167, 1977.
  26. Enna, S. J. , L. C. Murrin and M. J.    Autoradiography of Specific Reserpine Binding in the Rat Brain.  Trans.  Am.  Soc.  Neurochem.  8, 192, 1977.
  27. Uhl, G. R. , M. J. Kuhar and S. H.    Immunohistochemical Localization of Neurotensin and Enkephalin in Rat CNS.  Soc.  Neurosci.  Abstr.  3, 417, 1977.
  28. Murrin, L. C. , M. S. Lewis, N.  Klemm and M. J.    Activation of Synaptosomal Transport Systems by Depolarization.  Soc.  Neurosci.  Abstr.  3, 411, 1977.
  29. Murrin, L. C. , J. T. Coyle and M. J.    Effects of Lesions on Striatal Opiate Receptors.  Fed.  Proc.  37, 374, 1978.
  30. Murrin, L. C. , A. T. Malouf, N.  Klemm and M. J.    Light Microscopic Autoradiography of the Dopamine Receptor.  Trans.  Amer.  Soc.  Neurochem.  9, 124, 1978.
  31. Kuhar, M. J. Histochemical Localization of the Enkephalins and Opiate Receptors.    Am.  Soc.  Neurochem.  9, 126B, 1978.
  32. Kuhar, M. J. and S. E.    Current Issues in Neural Peptide Research.  Trans.  Am.  Soc.  Neurochem.  9, 25, 1978.
  33. Murrin, L. C. , N. Klemm and M. J.    Neuroleptic/Dopamine Receptors: Biochemical and Autroadiographic Studies.  Soc.  Neurosci.  Abstr.  4, 298, 1978.
  34. Snyder, S. H. , G. R. Uhl, S.  Childers and M. J.    Enkephalin Dynamics and Neuronal Localization.  Seventh Internat.  Cong.  of Pharmacol. , 1978.
  35. Palacios, J. M. , W. S. Young, III and M. J.    Autoradiographic Localization of Histamine H1 Receptors in Brain.  Fed.  Proc.  38, 687, 1979.
  36. Young, III, W. S. and M. J.    Autoradiography of Opiate and Benzodiazepine Receptors: In vitro Labeling of Tissue Sections.  Fed.  Proc.  38, 687, 1979.
  37. Wamsley, J. K. , W. S. Young, III and M. J.    Enkephalin Immunoreactive Sites in Rat Forebrain: An Immunohistochemical Study.  Soc.  Neurosci.  Abstr.  5, 543, 1979.
  38. Kuhar, M. J. , N. Taylor, N.  Birdsall and E.    Electron Microscopic Localization of Cholinergic Muscarinic Receptors in Rat Brain.  Soc.  Neurosci.  Abstr.  5, 592, 1979.
  39. Palacios, J. M. , W. S. Young, III and M. J.    GABA Receptors: Autoradiographic Localization in Rat Cerebellum.  Soc.  Neurosci.  Abstr.  5, 596, 1979.
  40. Young, III, W. S. , M. K. Conrad and M. J.    Light Microscopic Autoradiographic Localization of Benzodiazepine Receptors in Mammalian Brain.  Soc.  Neurosci.  Abstr.  5, 602, 1979.
  41. Wamsley, J. K. , W. S. Young, III, J. M.  Palacios and M. J.    Autoradiographic Localization of Neurotransmitter Receptors in Cortex.  Trans.  Am.  Soc.  Neurochem.  11, 219, 1980.
  42. Young, III, W. S. and M. J.    Noradrenergic Alpha 1 and Alpha 2 Receptors: Light Microscopic Autoradiographic Localization.  Fed.  Proc.  39, 593, 1980.
  43. Palacios, J. M. , R. N. DeHaven and M. J.    Localization of Beta Adrenergic Receptors in Rat Brain by Light Microscopic Autoradiography.  Fed.  Proc.  39, 593, 1980.
  44. Kuhar, M. J. and W. S.  Young, III.  Methods for the Autoradiographic Localization of Drug and Neurotransmitter Receptors.  Sixth Internat.    and Cytochem.  Congress, p.  219, 1980.
  45. Kuhar, M. J. , W. S. Young III, J. M.  Palacios and J. K.    Radiohistochemical Localization of Drug and Neurotransmitter Receptors in Brain with the Light Microscope.  Sixth Internat.  Histochem.  and Cytochem.  Congress, p.  218, 1980.
  46. London, E. D. , J. M. Palacios, J. I.  Rapoport and M. J.    Local Cerebral Glucose Utilization Following Systemic Administration of GABAergic Agonist and Antagonist Drugs.  Soc.  Neurosci.  Abstr.  6, 7, 1980.
  47. Wamsley, J. K. , J. M. Palacios, D. L.  Niehoff and M. J.    Neurotransmitter and Drug Receptor Localization in the Retina.  Soc.  Neurosci.  Abstr.  6, 211, 1980.
  48. Niehoff, D. L. , J. M. Palacios and M. J.    Dopamine Receptors: Temperature Effects on 3H Spiperone and 3H N m Propylnorapomorphine Binding.  Soc.  Neurosci.  Abstr.  6, 252, 1980.
  49. Palacios, J. M. , D. L. Niehoff and M. J.    Spiperone Binding Sites in Rat Brain: Light Microscopic Autoradiographic Localization of Dopamine and Other Receptors.  Soc.  Neurosci.  Abstr.  6, 498, 1980.
  50. Young, III, W. S. , J. K. Wamsely, M. A.  Zarbin and M. J.    Opioid Receptors Undergo Axonal Flow.  Soc.  Neurosci.  Abstr.  6, 498, 1980.
  51. Lewis, M. , J. K. Wamsley, W. S.  Young, III and M. J.    Autoradiographic Localization of Muscarinic Cholinergic Receptors in Rat Brain Stem.  Soc.  Neurosci.  Abstr.  6, 515, 1980.
  52. Goodman, R. R. , S. H. Snyder, M. J.  Kuhar and W. S.  Young, III.  Light Microscopic Autoradiographic Differentiation of Mu and Delta Opiate Receptors in Rat Brain.    Neurosci.  Abstr.  6, 523, 1980.
  53. Zarbin, M. A. , J. K. Wamsley and M. J.    Glycine Receptor Localization in Rat Brain by Radiohistochemical Methods.  Soc.  Neurosci.  Abstr.  6, 359, 1980.
  54. Unnerstall, J. R. , J. M. Palacios and M. J.    Relationship Between GABA and Benzodiazepine Receptors: Quantitative Autoradiographic Studies.  Soc.  Neurosci.  Abstr.  6, 359, 1980.
  55. London, E. , M. Dam, J. M.  Palacios, M. J.  Kuhar and S.    Relations of Metabolic Drug Responses to Receptor Distribution.  Trans.  Amer.  Soc.  Neurochem.  1, 141, 1981.
  56. Zarbin, M. A. , J. K. Wamsley, J. M.  Palacios, R.  Innis and M. J.    beta adrenergic and Cholecystekinin Receptors Undergo Axonal Flow.  Trans.  Amer.  Soc.  Neurochem.  12, 125, 1981.
  57. Kuhar, M. J. , J. M. Palacios, D. L.  Niehoff, W. S.  Young, III and J. R.    Benzodiazepine and GABA Receptors: Autoradiographic Studies.  Neurosci.  Lett. (Suppl.  7): S7, 1981.
  58. Innis, R. B. , M. A. Zarbin, J. K.  Wamsley, S. H.  Snyder and M. J.    Autoradiographic Localization of Cholecystokinin Receptors in Guinea Pig Brain.  Soc.  Neurosci.  Abstr.  7, 430, 1981.
  59. Wamsley, J. K. , M. A. Zarbin, W. S.  Young, III and M. J.    Opioid Receptors in the Monkey Brain, Pituitary and Retina: Localization by Light Microscopic Autoradiography.  Soc.  Neurosci.  Abstr.  7, 433, 1981.
  60. Zarbin, M. A. , J. K. Wamsley and M. J.    High and Low Affinity Muscarinic Cholinergic Receptors Undergo Axonal Transport.  Soc.  Neurosci.  Abstr.  7, 487, 1981.
  61. Unnerstall, J. M. , J. M. Palacios and M. J.    Opiate/Alpha 2 Interactions: Co Localization of Both Receptors by Radiohistochemistry.  Soc.  Neurosci.  Abstr.  7, 501, 1981.
  62. Palacios, J. M. , J. R. Unnerstall, D. L.  Niehoff, L.  Buhle and M. J.    Receptor Autoradiography with Tritium Sensitive Sheet Film: Analysis by Computerized Densitometry.  Soc.  Neurosci.  Abstr.  7, 614, 1981.
  63. Niehoff, D. L. , J. M. Palacios, M. J.  Kuhar, R.  O’Brien and D.    Benzodiazepine “Type 1” Receptors: A Biochemical Study.  Soc.  Neurosci.  Abstr.  7, 738, 1981.
  64. Lewis, M. , J. M. Palacios, J. R.  Unnerstall, D. L.  Niehoff, M.  Molliver and M. J.    The Perinatal Development of Neurotransmitter Receptors Studied by Autoradiographic Methods.  Soc.  Neurosci.  Abstr.  7, 401, 1981.
  65. Unnerstall, J. R. , T. A. Kopajtic, M. W.  Deitch and M. J.    Specificity and Potency of Guanabenz at the Alpha 2 Adrenergic Receptor.  Fed.  Proc.  41, 1667, 1982.
  66. Kuhar, M. J. Drug and Neurotransmitter Receptors in Aging.  13th CINP Congress, Vol.  1, p.  410, 1982.
  67. Unnerstall, J. R. , L. M. Orensanz, I.  Fernandez and M. J.    On the Selectivity of WB4101 as an Alpha 1 Ligand: An Autoradiographic Study.  Neurosci.  Lett.  (Suppl.  10: 5494, 1982.
  68. Wamsley, J. K. , M. A. Zarbin and M. J.    Autoradiographic Localization of High and Low Affinity Muscarinic Cholinergic Binding Sites in the Brain and Spinal Cord.  Soc.  Neurosci.  Abstr.  8, 21, 1982.
  69. Kuhar, M. J. and J. R.    In vitro Labeling Receptor Autoradiography: Loss of Ligand During Preparation.  Soc.  Neurosci.  Abstr.  8, 134, 1982.
  70. Uhl, G. R. , P. J. Whitehouse, C. L.  White, III, J. C.  Hedreen, R. E.  Carraway, D. L.  Price and M. J.    Neuro¬tensin Systems in Human Substantia Nigra: Normal/Parkinson’s Disease.  Soc.  Neurosci.  Abstr.  8, 142, 1982.
  71. Whitehouse, P. J. , J. K. Wamsley, M. A.  Zarbin, D. L.  Price, W. W.  Tourtellotte, L.  Davis and M. J.    Amyotrophic Lateral Sclerosis: Alterations in Neurotransmitter Receptors.  Soc.  Neurosci.  Abstr.  8, 153, 1982.
  72. Goodman, R. R. , M. J. Kuhar and A. S.    Light Microscopic Autoradiography of Mu and Delta Opiate Binding Sites in Mouse CNS.  Soc.  Neurosci.  Abstr.  8, 221, 1982.
  73. Niehoff, D. L. and M. J.    Benzodiazepine Receptors: Autoradiographic Localization in Rat and Human Amygdala.  Soc.  Neurosci.  Abstr.  8, 645, 1982.
  74. Unnerstall, J. R. , T. A. Kopajtic and M. J.    3H Rauwolscine and 3H Para Aminoclonidine: Autoradio¬graphic Analysis of the Distribution of Alpha 2 Binding Sites Labeled With Antagonists or Agonists.  Soc.  Neurosci.  Abstr.  8, 658, 1982.
  75. Valdes, J. J. , J. R. Unnerstall and M. J.    The Binding of 3H WB4101 and 3H Prazosin Differs in the Hippocampus of the Rat.  Soc.  Neurosci.  Abstr.  8, 659, 1982.
  76. Ko, G. N. , W. J. Freed, D. L.  Niehoff, E.  Cannon Spoor, J. M.  Morihisa, M. J.  Kuhar, B. J.  Hoffer and R. J.    Tissue Transplants in Rat Brain: Rotational Behavior and Dopamine Supersensitivity.  Soc.  Neurosci.  Abstr.  8, 748, 1982.
  77. Zarbin, M. A. , J. M. Palacios, J. K.  Wamsley and M. J.    Axonal Transport of Beta Adrenergic Receptors in Rat Sciatic Nerve.  Soc.  Neurosci.  Abstr.  8, 827, 1982.
  78. Lepor, H. and M. J.    Cholinergic Muscarinic Receptor Characteristics in the Genitourinary Tissues of the Rabbit and Rat.  The Pharmacologist (K.  A.  Crocker, ed. ) 25, 334, 1983.
  79. Summers, R. J. and M. J.    Beta Adrenoceptors in Rat Kidney Characterization and Autoradio¬graphic Localization Using 125I Cyanopindolol.  The Pharmacologist (K.  A.  Crocker, ed. ) 25, 484, 1983.
  80. Zarbin, M. A. , M. J. Kuhar, T.  O’Donohue, S.  Wolfe and T.    Autoradiography of Receptors for Bombesin in Mammalian Brain.  Soc.  Neurosci.  Abstr.  9, 589, 1983.
  81. Smith, G. T. , T. H. Moran, J. T.  Coyle, M. J.  Kuhar, T. L.  O’Donohue and P. R.    Autoradio¬graphic Localization of CCK Receptors in the Pyloric Sphincter of the Rat.  Soc.  Neurosci.  Abstr.  9, 172, 1983.
  82. Uhl, G. R. and M. J.    Nigra Neurotensin Receptors: Effects of Chronic Neuroleptic Treatment.  Soc.  Neurosci.  Abstr.  9, 172, 1983.
  83. Lo, M. M. S. , D. L. Niehoff, M. J.  Kuhar and S. H.    Differential Localization of Type 1 and Type 2 Benzodiazepine Receptor Sites in the Substantia Nigra.  Soc.  Neurosci.  Abstr.  9, 174, 1983.
  84. De Souza, E. B. , M. H. Perrin, J. E.  Rivier, W. W.  Vale and M. J.    Corticotropin Releasing Factor Binding Sites in Rat Pituitary Gland.  Soc.  Neurosci.  Abstr.  9, 391, 1983.
  85. Whitehouse, P. J. , W. L. Wahl, S.  Folstein, D.  Price and M. J.    Huntington’s Disease: An in vitro Receptor Autoradiographic Study of Neurotransmitter Receptors in the Basal Ganglia and Cortex.  Soc.  Neurosci.  Abstr.  9, 1053, 1983.
  86. Lynch, D. , P. J. Whitehouse and M. J.    Neurotransmitter Receptors: Effects of Postmortem Delay on a Rat Model of the Human Autopsy Process.  Soc.  Neurosci.  Abstr.  9, 1054, 1983.
  87. Unnerstall, J. R. , M. A. Zarbin and M. J.    Alpha 2 Adrenergic Receptors: Presence and Flow in Sciatic Nerve.  Soc.  Neurosci.  Abstr.  9, 1119, 1983.
  88. Troncoso, J. C. , P. J. Whitehouse, M. J.  Kuhar, J. W.  Griffin, L. C.  Cork and D. L.    Changes of Motor Neuron Cholinergic Receptors After Axotomy.  J.  Neuropathol.  Exp.  Neurol.  42, 313, 1983.
  89. Unnerstall, J. R. , R. D. Mashall, E. B.  De Souza and M. J.    Receptors Autoradiography in Brain: Coping with Regional Differences in Autoradiographic Efficiency with Tritium.  Fed.  Proc.  43, 24, 1984.
  90. Titeler, M. , E. B. De Souza and M. J.    3H Nitrendipine Binding to Calcium Channels in Bovine and Rat Pituitary.  Soc.  Neurosci.  Abstr.  10, 86, 1984.
  91. De Souza, E. B. and M. J.    Beta2 Adrenergic Receptors in Pituitary: Identification, Characterization and Autoradiographic Localization.  Soc.  Neurosci.  Abstr.  10, 86, 1984.
  92. Ko, G. N. , J. R. Unnerstall, H. H.  Holcomb, J. E.  Kleinman and M. J.    Human Locus Ceruleus Auto-radiography: Alpha2 Adrenergic and Opiate Receptors.  Soc.  Neurosci.  Abstr.  10, 234, 1984.
  93. Anholt, R. R. H. , E. B. De Souza, M. J.  Kuhar and S. H.    Association of Peripheral Type Benzodiaze¬pine Receptors With Endocrine Cells in Rat Pituitary, Adrenal and Testis.  Soc.  Neurosci.  Abstr.  10, 477, 1984.
  94. Insel, T. R. , E. B. De Souza, M.  Perrin, J.  Rivier, W. W.  Vale and M. J.    Corticotropin Releasing Factor (CRF) Receptors: Identification in Brain by Autoradiography.  Soc.  Neurosci.  Abstr.  10, 217, 1984.
  95. Taylor, N. R. , J. R. Unnerstall, R. D.  Mashall, E. B.  De Souza and M. J.    Receptor Autoradiography: Coping with Regional Differences in Autoradiographic Efficiency with Tritium.  Soc.  Neurosci.  Abstr.  10, 557, 1984.
  96. Kuhar, M. J. , P. J. Whitehouse, J. R.  Unnerstall and H.    Receptor Autoradiography: Analysis Using a PC Based Imaging System.  Soc.  Neurosci.  Abstr.  10, 558, 1984.
  97. Unnerstall, J. R. , M. J. Kuhar, R.  Grzanna and L. P.    Alpha 2 Binding Sites in the Thoracic Spinal Cord: Autoradiographic Evidence for Postsynaptic Localization in the Intermediolateral Cell Column.  Soc.  Neurosci.  Abstr.  10, 713, 1984.
  98. Whitehouse, P. J. , B. E. Jones, T. A.  Kopajtic, D. L.  Price and M. J.    Receptors in the Nucleus Basalis of Primates: An in vitro Autoradiographic Study.  Ann.  Neurol.  16, 118, 1984.
  99. Troncoso, J. C. , L. C. Cork, P. J.  Whitehouse, M. J.  Kuhar and D. L.    Canine Inherited Ataxia: Neurotransmitter Receptors in the Cerebellum.  Ann.  Neurol.  16, 135, 1984.
  100. Wagner, H. N. , D. F. Wong, R. F. Dannals, J. J.  Frost, G.  Pearlson, H. T.  Ravert, J. M.  Links, M.  Titeler and M. J.    Imaging of S2 Serotonin Receptors in the Human Cerebral Cortex with in vivo Positron Emission Tomography.  Soc.  Neurosci.  Abstr.  10, 1092, 1984.
  101. Wong, D. F. , H. N. Wagner, Jr. , R. F. Dannals, J. J.  Frost, H. T.  Ravert, J. M.  Links, M.  Folstein, G.  Uhl, L.  Tune, S.  Folstein, H.  Singer, T.  Preziosi and M. J.    D2 Dopamine Receptors in Normal and Pathological States Imaged by Positron Tomography.  Soc.  Neurosci.  Abstr.  10, 1092, 1984.
  102. Frost, J. J. , H. N. Wagner, Jr. , R. F. Dannals, H. T.  Ravet, A. A.  Wilson, J. M.  Links, D. F.  Wong, H. D.  Burns, H. D. , Snyder, S. H. , and Kuhar, M. J.  Imaging Opiate Receptors with Positron Emission Tomography.    Neurosci.  Abstr.  10: 1091, 1984.
  103. Wong, D. F. , H. N. Wagner, Jr. , R. F. Dannals, J. J.  Frost, H. T.  Ravert, J. M.  Links, M. F.  Folstein, B. A.  Jensen, M. J.  Kuhar and J. T.
  104. Uhl, G. R. , G. O. Hackney, P. J. Whitehouse, R. J.  Maschall, D. L.  Price and M. J.    Neuroleptic-Induced Changes in Substantia Nigra Neurotensin Receptor Binding: Parallels with Tardive Dyskinesia.  Neurology 34(Suppl.  1): 104, 1984.
  105. Whitehouse, P. J. , R. Rajagopalan, C. A. Kitt, B. E.  Jones, D. L.  Niehoff, M. J.  Kuhar and D. L.    Muscarinic Cholinergic Receptors in the Amygdala in Alzheimer’s Disease.  Neurology 34 (Suppl.  1): 121, 1984.
  106. Whitehouse, P. J. , J. C. Troncoso, L. C. Cork, O.  Muramoto, I.  Kanazawa, T. A.  Kopajtic, D. L.  Price and M. J.    Alterations of Neurotransmitter Receptors in Cerebelluar Degeneration Syndromes in Humans.  Neurology 34 (Suppl.  1): 127, 1984.
  107. Goeders, N. E. and M. J.  Benzodiazepine Receptor Labeling in vivo Using [3H] Ro 15 1788.  Trans.  Am.  Soc.  Neurochem.  16 (1), 44, 1985.
  108. Kuhar, M. J. , H. Wagner, D. Wong, J.  Frost, R.  Dannals and J.    Neurotransmitter Receptors: Noninvasive Studies By PET Scanning.  Trans.  Am.  Soc.  Neurochem.  16 (1), 437, 1985.
  109. Wong, D. F. , J. M. Links, H. N. Wagner, Jr. , S. E.  Folstein, S.  Suneja, R. F.  Dannals, H. T.  Ravert, A. A.  Wilson, L. E.  Tune, G.  Pearlson, M. F.  Folstein, A.  Bice and M. J.    Dopamine and Serotonin Receptors Measured in vivo in Huntington’s Disease with C 11 N Methylspiperone PET Imaging.  Society for Nuclear Medicine 32nd Annual Meeting, June 2 5, 1985, Houston, TX.
  110. Wong, D. F. , G. Pearlson, H. N. Wagner, Jr. , R. F.  Dannals, S.  Suneja, E.  Bjorgvinsson, J. M.  Links, H. T.  Ravert, A. A.  Wilson, F.  Schaerf, L. E.  Tune and M. J.    In vivo Assessment of Dopamine D 2 and Serotonin S 2 Receptors Measured by C 11 N Methylspiperone (NMSP) in Manic Depressive Illness.  Society of Nuclear Medicine 32nd Annual Meeting, June 2 5, 1985, Houston, TX.
  111. Wong, D. F. , L. E. Tune, H. N. Wagner, Jr. , S.  Suneja, E.  Bjorvinsson, G.  Pearlson, R. F.  Dannals, H. T.  Ravert, J. M.  Wilson, F.  Schaerf and M. J.    In vivo Assessment of Dopamine and Serotonin Receptors Measured by C 11 N Methyl Spiperone (NMSP) in Patients with Schizophrenia.  Society of Nuclear Medicine 32¬nd Annual Meeting, June 2 5, 1985, Houston, TX.
  112. Wong, D. F. , H. N. Wagner, Jr. , J. H. Coyle, S.  Snyder, R.  Dannals, N.  LaFrance, A.  Bice, G.  Pearlson, J.  Links, M.  Paulos, R.  Hoehn Saric, L.  Tune and M. J.    Assessment of Dopamine Receptor Blockade by Neuroleptic Drugs in the Living Human Brain.  Society for Nuclear Medicine 32nd Annual Meeting, June 2 5, 1985, Houston, TX.
  113. Wong, D. F. , A. Gjedde, H. N. Wagner, Jr. , K. H.  Douglass, R. F.  Dannals, S. H.  Snyder and M. J.    Further Development and Validation of the Model for in vivo Quantification of Human Dopamine Receptors.  Society of Nuclear Medicine 32nd Annual Meeting, June 2 5, 1985, Houston, TX.
  114. Applegate, A. V. , M. J. Kuhar and E. B. De Souza.  Corticotropin Releasing Factor (CRF) Receptors in Rat Brain.    Neurosci.  Abstr.  11, 13, 1985.
  115. Goeders, N. E. , M. J. Kuhar and E. B. De Souza.  Benzodiazepine Receptor Changes in Discrete Areas of Rat Brain Following Adrenalectomy.    Neurosci.  Abstr.  11, 278, 1985.
  116. Wong, D. F. , H. N. Wagner, Jr. , A. Gjedde, J.  Coyle, R. F.  Dannals, S.  Snyder, J.  Links and M. J.    Pet Quantification of Dopamine Receptors with Competitive Neuroleptic Drugs in the Living Human Brain.  Soc.  Neurosci.  Abstr.  11, 455, 1985.
  117. Goehring, S. B. , M. J. Kuhar and N. E.  [3H] Sulpiride Binding Site Changes Correlated with Chronic Cocaine Administration in Rats.  Soc.  Neurosci.  Abstr.  11, 630, 1985.
  118. Schmidt, W. K. , E. B. De Souza and M. J.  Nalbuphine: An Autoradiographic Opioid Receptor Binding Profile of an Agonist/ Antagonist Analgesic.  Soc.  Neurosci.  Abstr.  11, 758, 1985.
  119. Titeler, M. , R. A. Lyon, J. J. Frost, H. N.  Wagner, D. F.  Wong, R. F.  Dannals, J. M.  Links, P. J.  Whitehouse and M. J.    Properties of 3H Methyl Spiperone Binding to Human and Rat D2 and 5 HT2 Receptors in vitro.  Soc.  Neurosci.  Abstr.  11, 888, 1985.
  120. Kuhar, M. J. and N. E.  Benzodiazepine Receptor Labeling in vivo with [3H] Ro 15 1788.  Soc.  Neurosci.  Abstr.  11, 1056, 1985.
  121. Frost, J. J. , R. F. Dannals, H. T. Ravert, A. A.  Wilson, J. M.  Links, R.  Trifiletti, M. J.  Kuhar, S. H.  Snyder and H. N.  Wagner, Jr.  Imagining Benzodiazepine Receptors in Man with C 11 Suriclone and Positron Emission Tomography.    Neurosci.  Abstr.  11, 1121, 1985.
  122. Griffiths, R. R. , M. J. Kuhar and N. E.  Discriminative Stimulus Properties of Centrally Applied Midazolam: Generalization From Peripheral Training Conditions.  Soc.  Neurosci.  Abstr.  11, 1291, 1985.
  123. Whitehouse, P. J. , T. Kopajtic, B. E. Jones, M. J.  Kuhar and L. D.    An in vitro Receptor Autoradiographic Study of Muscarinic Cholinergic Receptor Subtypes in the Amygdala and Neocortex of Patients with Alzheimer’s Disease.  Neurology 35(Suppl.  1): 217, 1985.
  124. Kuhar, M. J. Receptor Mapping by Autoradiography. Proceedings RMS 21 (5), 273 274, 1986.
  125. Frost, J. J. , H. S. Mayberg, K. H. Douglass, R. F.  Dannals, H. D.  Ravert, A. A.  Wilson, J. M.  Links, M. J.  Kuhar, S. H.  Snyder and.   N.  Wagner, Jr.  11C Carfentanil Binding to Opiate Receptors in Man Using Positron Emission Tomography: Kinetic Modeling and Drug Effects.  Soc.  Neurosci.  Abstr.  12 (1), 173 174, 1986.
  126. Goeders, N. E. , M. Ritz and M. J.  Buspirone Increases in vivo Benzodiazepine Receptor Labeling: No Relation to Anxiolytic Activity.  Soc.  Neurosci.  Abstr.  12(1), 309, 1986.
  127. Wong, D. F. , A. Gjedde, N. H. Wagner, Jr. , L.  Tune, C.  Tamminga, R. F.  Dannals, J.  Williams, L.  O’Tuama, J.  Links, H. T.  Ravert, A. A.  Wilson, E.  Broussolle, M. J.    In vivo Absolute Receptor Density Estimates in Schizophrenia and Normal Aging: Preliminary Studies with C 11 NMSP PET Imaging.  Soc.  Neurosci.  Abstr.  12(1), 564, 1986.
  128. Webster, E. L. , M. J. Kuhar and E. B. De Souza.  Corticotropin Releasing Factor (CRF) Receptors in Mouse Spleen: Identification and Characterization.    Neurosci.  Abstr.  12(2), 1067, 1986.
  129. O’Hearn, E. , G. Battaglia, E. B. De Souza, M. J.  Kuhar and M. E.    Systemic MDA and MDMA, Psycho-tropic Substituted Amphetamines, Produce Serotonin Neurotoxicity.  Soc.  Neurosci.  Abstr.  12(2), 1233, 1986.
  130. Battaglia, G. , M. J. Kuhar and E. B. De Souza.  MDA and MDMA (Ecstasy) Interactions with Brain Serotonin Receptors and Uptake Sites: In vitro Studies.    Neurosci.  Abstr.  12(2), 1234, 1986.
  131. Yeh, S. Y. , G. Battaglia, E. O’Hearn, M. E.  Molliver, M. J.  Kuhar and E. B.  De Souza.  Effects of MDA and MDMA (Ecstasy) on Brain Monoaminergic Systems: In vivo Studies.    Neurosci.  12 (2), 1986.
  132. Battaglia, G. , M. J. Kuhar and E. B. De Souza.  MDMA Induced Neurotoxicity Visualized by in vitro Autoradiography: Differential Sensitivity of Serotonergic Neurons.    Proc.  46(3), 404, 1987.
  133. Ritz, M. C. and M. J.  The Cocaine Receptor: Behavioral Potency Correlates with Monoamine Uptake Inhibition.  Fed.  Proc.  46 (3), 404, 1987.
  134. Kuhar, M. J. Human Brain Imaging.  Cell Biochem. (Suppl.  11D): 174.  1987.
  135. Ritz, M. C. , R. J. Lamb, S. R. Goldberg and M. J.    Cocaine Receptors on Dopamine Transporters Mediate Drug Self administration.  The Pharmacologist 29 (3), 160, 1987.
  136. Sharkey, J. and M. J.  3H GBR 12935 Labels the Cocaine Binding Site Associated with Dopamine Uptake Inhibition.  The Pharmacologist 29 (3), 160, 1987.
  137. Ritz, M. C. , J. Sharkey and M. J.  Cocaine Inhibits QNB Binding to Muscarinic Receptors in Rat Brain and Heart.  Soc.  Neurosci.  Abstr.  42 (5), 144, 1987.
  138. Sharkey, J. and M. J.  The Cocaine Binding Site Associated with Dopamine Uptake Inhibition as Labeled by 3H GBR 12935.  Soc.  Neurosci.  Abstr.  42 (4), 144, 1987.
  139. Wong, D. F. , G. Pearlson, C. Ross, L.  Tune, V.  Villemagne, R. F.  Dannals, J.  Links, H.  Ravert, A.  Wilson, M.  Kuhar, H. N.  Wagner, Jr.  and A.    In vivo Measurement of D2 Dopamine Receptor Abnormalities in Drug Naive and Drug Free Manic Depressive Patients.  Soc.  Neurosci.  Abstr.  13 (1), 216, 1987.
  140. Lyon, R. A. , M. Titeler, L. T. Rydelek, A. E.  Bullock, J. J.  Frost, R.    Dannals and M. J.  Kuhar.  Properties of 3H Carfentanil Binding to Human and Rat Brain Opiate Receptors in vitro.  Soc.  Neurosci.  Abstr.  14 (1), 105, 1988.
  141. Sanchez Roa, P. M. , J. Sharkey, A. A. Wilson, D. E.  Grigoriadis, R. F.  Dannals, D. F.  Wong and M. J.    [125I] Spectramide: A Novel Benzamide Ligand Displaying Potent and Selective Effects at the D2 Dopamine Receptor.  Soc.  Neurosci.  Abstr.  14 (1), 411, 1988.
  142. Battaglia, G. , J. Sharkey, M. J. Kuhar and E. B.  De Souza.  Neuroanatomical Specificity of MDA and MDMA Induced Degeneration of Serotonin Neurons in Rat Brain.    Neurosci.  Abstr.  222 (5), 557, 1988.
  143. Johannessen, J. N. , T. R. Insel, G. Battaglia, M. J.  Kuhar and E. B.  De Souza.  MDMA Selectively Destroys Brain Serotonin Terminals in Rhesus Monkeys.    Neurosci.  Abstr.  14 (1), 557, 1988.
  144. Kuhar, M. J. , J. Sharkey and D. E.  Solubilization of the Dopamine Transporter.  Soc.  Neurosci.  Abstr.  14 (2), 930, 1988.
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  146. Porrino, L. , L. Sharpe, M. Ritz, N.  Goodman, S.  Goldberg and M.    Differential Effects of the Manipulation of Serotonin Systems on Intravenous Amphetamine and Cocaine Self-administration in Rats.  NIDA Research Monograph Series No.  90.  Problems of Drug Dependence 1988: Proceedings of the 50th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  29, 1988.
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  148. Lew, R. , D. E. Grigoriadis, A. A. Wilson and M. J.    Dopamine Transporter in Rat Caudate Putamen is Glycosylated.  Soc.  Neurosci.  Abstr.  15 (1), 107, 1989.
  149. Goldberg, S. R. , M. J. Kuhar, J. L. Katz and J. M.    Modulation of the Lethal Effects of Cocaine by Cholinomimetics.  Soc.  Neurosci.  Abstr.  15 (1), 252, 1989.
  150. Boja, J. W. and M. J.  3H WIN 35,065 2 (3H WIN) Binding is Similar in Various Brain Regions of the Rat.  Soc.  Neurosci.  Abstr.  15 (2), 1092, 1989.
  151. Ritz, M. C. , J. W. Boja, F. I. Carroll, A. H.  Lewin and M. J.    3H WIN 35,065 2 (3H WIN): A Ligand for Cocaine Receptors in Rat Striatum.  Soc.  Neurosci.  Abstr.  15 (2), 1092, 1989.
  152. Ritz, M. C. , J. W. Boja, F. R. George and M. J.    Cocaine Binding Sites Related to Drug Self-adminis¬tration.  NIDA Research Monograph Series No.  95.  Problems of Drug Dependence 1989: Proceedings of the 51st Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  239, 1989.
  153. Wong, D. F. , D. Young, L. T. Young, L. E.  Tune, G.  Pearlson, E.  Minkin, C.  Meltzer, Cidis, K.  Midha, R. F.  Dannals, H. T.  Ravert, A. A.  Wilson, E. D.  London, H. N.  Wagner, Jr. , M.  Casanova, J.  Klineman, M. J.  Kuhar and A.    Validation of PET D2 Dopamine Receptor Quantification Using [C 11] NMSP and [F 18] Haloperidol.  Soc.  Neurosci.  Abstr.  15 (2), 1132, 1989.
  154. Lew, R. , J. W. Boja, A. Wilson and M. J.    Identification of the Dopamine Transporter in Various Regions of the Rat Brain Using the Photoaffinity Radioligand [125I]DEEP.  FASEB J.  4(3): 342, 1990.
  155. Carroll, F. I. , J. W. Boja, A. Philip, A. H.  Lewin, and M. J.    Structure Activity Relationships of Ring and Side group Substitutions of the Cocaine Molecule.  FASEB J.  4(3): 343, 1990.
  156. Boja, J. W. , A. Lewin, F. I. Carroll and M. J.    Irreversible Binding to the Cocaine Receptor by Meta and Para isothiocyanato benzoylecgonine Methyl Ester.  FASEB J.  4(3): 344, 1990.
  157. Scheffel, U. , J. W. Boja, M. Stathis and M. J.    In vivo Labeling of Cocaine Receptors with 3H ( )Cocaine, 3H WIN 35,065 2 and 3H WIN 35,428.  FASEB J.  4 (3), 2781, 1990.
  158. Vaughan, R. A. , R. Simantov, R. Lew, E.  Webster and M. J.    A Rapid Binding Assay for Soluble Dopamine Transporters.  Soc.  Neurosci.  Abstr.  16 (1), 745, 1990.
  159. Scheffel, U. , R. F. Dannals, A. A. Wilson, H. T.  Ravert, J. W.  Boja, M.  Stathis and M. J.    3H/11C WIN 35,428 Labels the Cocaine Receptor in vivo.  Soc.  Neurosci.  Abstr.  16 (1), 746, 1990.
  160. Lew, R. , J. W. Boja, R. Simantov, F. I.  Carroll, A.  Lewin and M. J.    New Photaffinity Probes for the Cocaine Receptor.  Soc.  Neurosci.  Abstr.  16 (1), 746, 1990.
  161. Boja, J. W. , T. Kopajtic, F. I. Carroll, A.  Lewin and M. J.    High Affinity Inhibition of the Cocaine Binding Site by Novel Cocaine Analogs.  Soc.  Neurosci.  Abstr.  16 (1), 746, 1990.
  162. Carroll, F. I. , M. A. Rahman, A. Philip, A. H.  Lewin, J. W.  Boja and M. J.    Synthesis and Receptor Binding of Cocaine Analogs.  NIDA Research Monograph Series No.  105.  Problems of Drug Dependence 1990: Proceedings of the 52nd Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  147, 1990.
  163. Boja, J. W. , F. I. Carroll, M. A. Rahman, A.  Philip, A. H.  Lewin and M. J.    Cocaine Analogs: Binding Affinities at the Monoamine Transporters.  The Pharmacologist 33 (3), 161, 1991.
  164. Shimada, S. , S. Kitayama, C. Liang Lin, A.  Patel, M.  Kuhar, P.  Gregor and G. R.    Diversity of Neurotransmitter Transporter cDNAs in Brain Libraries.  Soc.  Neurosci.  Abstr.  17 (2), 1182, 1991.
  165. Pilotte, N. S. , J. W. Boja, L. G. Sharpe, E. P.  Kornak and M. J.    Withdrawal of Chronic Cocaine Decreases Binding of [3H]WIN 35,428 in the Rat Nucleus Accumbens.  Soc.  Neurosci.  Abstr.  17(1), 154, 1991.
  166. Lew, R. , R. Vaughan, R. Simantov and M. J.    Multiple Dopamine Transporters: Different Molecular Weights in Rat Striatum and Nucleus Accumbens.  Soc.  Neurosci.  Abstr.  17(1), 155, 1991.
  167. Cline, E. J. , U. Scheffel, J. W. Boja, W. M.  Mitchell, F. I.  Carroll and M. J.    In vivo Binding to Dopamine and Serotonin Uptake Sites in the Mouse with the Cocaine Analog [125I] RTI 55; Autoradiography, Regional Distribution, and Pharmacology.  Soc.  Neurosci.  Abstr.  17(1), 155, 1991.
  168. M. Mitchell, J. W. Boja, E. J.  Cline, R.  Lew, F. I.  Carroll, A.  Lewin and M. J.  Kuhar.  In vitro Autoradio¬graphic Characterization of 3 [4 Iodophenyl] tropane 2 carboxylic Acid Methyl Ester [125I]RTI 55) Binding to Dopamine and Serotonin Uptake Sites in Rat Brain.  Soc.  Neurosci.  Abstr.  17(1), 155, 1991.
  169. Boja, J. W. , A. Patel, F. I. Carroll, M. A.  Rahman, A.  Philip, A. H.  Lewin, R.  Vaughan, T. A.  Kopajtic and M. J.    [125I]RTI 55: A High Affinity Ligand for the Dopamine Transporter.  Soc.  Neurosci.  Abstr.  17 (1), 189, 1991.
  170. Patel, A. , J. W. Boja, J. Lever, R.  Lew, R.  Simantov, F. I.  Carroll, A. H.  Lewin, A.  Philip, Y.  Gao, R.  Vaughan and M. J.    A Cocaine Analog and a GBR Analog Both Label the Same Protein in Rat Striatal Membranes.  Soc.  Neurosci.  Abstr.  17 (1), 189, 1991.
  171. Appel, N. M. , S. A. Matthews, G. M. Storti and M. J.    Storage Phosphors as an Alternative to Photo¬graphic Emulsion for Recording and Quantifying Autoradiograms.  Soc.  Neurosci.  Abstr.  17 (1), 373, 1991.
  172. Scheffel, U. , R. F. Dannals, E. J. Cline, M.  Stathis, C.  Steinert, F. I.  Carroll and M. J.    In vivo Labeling of Dopamine and Serotonin Uptake Sites in the Rat Brain with [123I] RTI 55.  Soc.  Neurosci.  Abstr.  17, 414, 1991.
  173. Boja, J. W. , A. Patel, T. A. Kopajtic, W. M.  Mitchell, F. I.  Carroll, M. A.  Rahman, P.  Abraham, A. H.  Lewin and M. J.    [125I]RTI-55: A Potent Ligand for the Cocaine Receptor.  NIDA Research Monograph Series No.  119.  Problems of Drug Dependence 1991: Proceedings of the 53rd Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  234, 1991.
  174. Lew, R. , R. Vaughan, R. Simantov and M. J.    Comparison of the Molecular Weight of the Dopamine Transporter in Rat Nucleus Accumbens and Striatum.  NIDA Research Monograph Series No.  119.  Problems of Drug Dependence 1991: Proceedings of the 53rd Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  238, 1991.
  175. Boja, J. W. , F. Carroll, D.  Wong, R.  Dannals, U.  Scheffel, R.  Vaughan, E.  Cline, A.  Patel and M. J.  Kuhar.  Dopamine Transporter as a Cocaine Receptor: Recent Imaging and Molecular Studies.  Behav.  Pharmacol. , 3 (1), 27-28, 1992.
  176. Cerruti, C, S. Shimada, D. Walther, M.  Kuhar and G.    Dopamine Transporter 1 mRNA Densities Differ Among Neurons of Different Dopaminergic Nuclei.  Soc.  Neurosci.  Abstr.  18 (1), 474, 1992.
  177. Boja, J. W. , F. I. Carroll, A. H. Lewin, Y.  Gao, P.  Abraham, K.  Parham, T.  Kopajtic, M.  Milberger, R. M.  McNeill and M. J.    Structural Modifications of Cocaine: Increased Selectivity for the Dopamine Transporter.  NIDA Research Monograph Series No.  132.  Problems of Drug Dependence 1991: Proceedings of the 54th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  129, 1992.
  178. Wong, D. F. , J. Harris, B. Yung, R. F.  Dannals, H. T.  Ravert, C.  Chen, M.  Yaster, J.  Neumeyer, R.  Carpenter, W.  Nyhan, H. N.  Wagner, Jr. , M. J.  Kuhar and G.    In vivo Pet Imaging and Quantification of Dopa¬mine Transporter Sites with 11C-WIN 35,428 in Lesch Nyhan Syndrome.  Soc.  Neurosci.  Abstr.  18, 3, 1992.
  179. Lakoski, J. M. , H. Zheng, J. W. Boja, F. I.  Carroll and M. J.    Potent Phenyltropane Cocaine Analogs Inhibit Serotonin (5-HT) Dorsal Raphe Cell Firing.  Soc.  Neurosci.  Abstr.  18 (1), 722, 1992.
  180. Kopajtic, T. A. , J. Boja, M.  Milberger, F. I.  Carroll, A. H.  Lewin, P.  Abraham, K.  Parham and M. J.  Kuhar.  The Dopamine Transporter: Selective Inhibition by Novel Cocaine Analogs.  Soc.  Neurosci.  Abstr.  18, 722, 1992.
  181. Cline, E. J. , N. S. Pilotte, W. M. Mitchell, U.  Scheffel and M. J.    Effect of Repeated Administration of [3H]WIN 35,428 Binding in vivo in Dorsal and Ventral Striatum and Midbrain; Regional Dissection and Quantitative Autoradiography.  Soc.  Neurosci.  Abstr.  18 (1), 723, 1992.
  182. Patel, A. , L. Markham, R. Lew, G.  Uhl and M. J.    Dopamine Transporter: Species Differences in Molecular Weight.  Soc.  Neurosci.  Abstr.  18 (2), 1433, 1992.
  183. Vaughan, R. A. , M. T. McCoy and M. J.  Charge Isoforms of Dopamine Transporters.  Soc.  Neurosci.  Abstr.  18 (2), 1433, 1992.
  184. Pilotte, N. S. and E. P.  Basal Prolactin, but Not Growth Hormone, is Elevated in Adult Male Rats Given Cocaine Prenatally.  NIDA Research Monograph Series No.  132.  Problems of Drug Dependence 1992: Proceedings of the 54th Annual Scientific Meeting, p.  113, 1992.
  185. Patel, A. , C. Cerruti, and M. J.  Changes in Molecular Mass of Rat Striatal Dopamine Transporter During Postnatal Development.  Soc.  Neurosci.  Abstr.  19 (1), 3, 1993.
  186. Vaughan, R. , W. M. Mitchell, C. R. Freed, G.  Uhl and M. J.  Kuhar, M. J.  Dopamine Transporter Antibodies.    Neurosci.  Abstr.  19 (1), 745, 1993.
  187. Kuhar, M. J. and S. Pögün S.  Modulation of Dopamine Transport by Nitric Oxide (NO).    Neurosci.  Abstr.  19 (2), 937, 1993.
  188. Pögün, S. and M. J.  Glutamic Acid (GLU) Uptake Inhibition by Nitric Oxide (NO).  Soc.  Neurosci.  Abstr.  19 (2), 1351, 1993.
  189. Cerruti, C. , N. S. Pilotte, G. Uhl, and M. J.    Reduced VTA Dopamine Transporter mRNA Occurs After Cessation of Chronic Cocaine Administration.  Soc.  Neurosci.  Abstr.  19 (2), 1498, 1993.
  190. Boja, J. W. , T. A. Kopatjic, F. I. Carroll, H. H.  Seltzman, C. D.  Wyrick, J.  Lever, J.  Staley, D. C.  Mash, and M. J.    Selective Labeling of the Striatal and Cerebral Cortical Dopamine Transporter in Rat and Human Brain by the Cocaine Analog [125I]RTI-121.  Soc.  Neurosci.  Abstr.  19 (2), 1498, 1993.
  191. Kopajtic, T. A. , J. W. Boja, F. I. Carroll, J. L.  Grey, M. A.  Kuzemko, A. H.  Lewin, P.  Abraham and M. J.    Oxidiazol Analogs of Cocaine: Selective and Esterase Resistant Ligands for the Dopamine Transporter.  Soc.  Neurosci.  Abstr.  19 (3), 1843, 1993.
  192. Pilotte, N. S. , L. G. Sharpe, and M. J.  Delayed Reduction of Dopamine Transporter Binding in Nucleus Accumbens after Termination of Repeated Passive Infusions of Cocaine.  Soc.  Neurosci.  Abstr.  19, 1858, 1993.
  193. Stathis, M. , U. Scheffel, J. W. Boja and M. J.    Rates of Occupancy of Central Dopamine Transporters by Novel Cocaine Analogs.  Soc.  Neurosci.  Abstr.  19(3): 1859, 1993.
  194. Cerruti, C. , N. Pilotte, G. Uhl, and M. J.    Withdrawal of Cocaine Reduces the Dopamine Trans¬porter mRNA Expression in Two Ventral Tegmental Area Subnuclei.  J.  Neurochem.  61, 569, 1993.
  195. Boja, J. W. , U. Scheffel, D. Wong, R.  Dannals, E.  Shaya, F. I.  Carroll, A. H.  Lewin, P.  Abraham, and M. J.    [123/125I]RTI-121: A Selective in vitro and in vivo Binding Ligand for the Dopamine Transporter.  NIDA Reasearch Monograph Series No.  141.  Problems of Drug Dependence, 1993: Proceedings of the 55th Annual Scientific Meeting, The College on Problems of Drug Depencence, Inc. , p.  99, 1994.
  196. Cline, E. J. , N. S. Pilotte, U. Scheffel, W. M.  Mitchell, and M. J.    Daily I. V.  Cocaine Infusion Decreases in vivo [3H] WIN 35,428 Autoradiographic Binding in Behaviorally Relevant Brain Areas following With¬¬drawal.  NIDA Research Monograph Series No.  141.  Problems of Drug Dependence, 1993: Proceedings of the 55th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  100, 1994.
  197. Cline, E. J. , P. Terry, U. Scheffel, J. W.  Boja, F. I.  Carroll, J. L.  Katz, and M. J.    Substituted 3-Phenyl-tropane Analogs of Cocaine; Effects on Behavior and on [3H]WIN 35,428 Binding in vivo.  NIDA Research Monograph Series No.  141.  Problems of Drug Dependence, 1993: Proceedings of the 55th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  101, 1994.
  198. Persico, A. M. , S. Reich, J. E. Henningfield, M. J.  Kuhar, and G. R.    Parkinsonian Patients Report Blunted Subjective Effects of Methylphenidate.  NIDA Research Monograph Series No.  141.  Problems of Drug Dependence, 1993: Proceedings of the 55th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  395, 1994.
  199. Kuhar, M. J. Recent Progress in Dopamine Transporter Research.  Eur.  Coll.  Neuropsychopharmacol.  4(3): 248-249, 1994.
  200. Kopajtic, T. K. , Boja, J. W. , Carroll, F. I. , Kotian, P. , Seltzman, H. H. , Wyrick, C. D. , Lewin, A. H. , and Kuhar, M. J. Binding To Striatal Dopamine Transporters by the Selective Cocaine Analog RTI-229.  Neurosci.  Abstr.  20(1), 922, 1994.
  201. Kuhar, M. J. , Boja, J. W. , Lewin, A. H. , Abraham, P. , Keverline, K. and Carrollm F. I. New Selective Compounds for the Serotonin Transporter: Synthesis and Ligand Binding of Cocaine Analogs.    Neurosci.  Abstr.  20(1), 293, 1994.
  202. Boja, J. W. , Cadet, J. L. , Carroll, F. I. , Lewin, A. H. , Abraham, P. , and Kuhar M. J. Identification of a Novel [125I]RTI-121 Binding Site in Rat Cerebral Cortex: A Possible Site of Antidepressant Action.  Neurosci.  Abstr.  20(2), 1636, 1994.
  203. Grant, S. , Revay, R. , Vaughan, R. , Freed, C. , Uhl, G. and Kuhar, M. J. Immunohistochemical Localization of Dopamine Transporters in Rat Brain.    Neurosci.  Abstr.  20(1), 920, 1994.
  204. Carroll, F. I. , Kuhar, M. J. , Kopajtic, T. , Yang, E. , Abraham, P. , Lewin, A. H. , and Boja, J. W. Secon¬dary Amine Analogs of 3-(4′-Substituted Phenyl)Tropane-2-Carboxylic Acid Esters and N-Norcocaine Exhibit Enhanced Affinity for Serotonin and Norepinephrine Transporters. Proceedings of the 56th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , Abstracts, 2, p.  509, 1994.
  205. Scheffel, U. , Carroll, F. I. , Kepler, J. A. , Taylor, G. F. , Stathis, M. , London, E. D. , and Kuhar, M. J. In vivo Labeling of Nicotinic Acetylcholine Receptors With (+) and (-) [3H]Norchloroepibatidine.  Nucl.  Med.  36(5), 253P, 1995.
  206. Scheffel, U. , Kellar, K. J. , Kimes, A. S. , Kuhar, M. J. , and London, E. D. In vivo Labeling of Nicotinic Cholinergic Receptors in Brain Using [3H]Epibatidine.  Nucl.  Med.  36(5), 253P, 1995.
  207. 207Nirenberg, M. J. , Vaughan, R. A. , Uhl, G. R. , Kuhar, M. J. , and Pickel, V. M. The Dopamine Transporter is Localized to Axonal and Dendritic Plasma Membranes of Nnitrostriatal Dopaminergic Neurons.    Neurosci.  Abstr.  21(1): 373, 1995.
  208. Martel, J. C. , Cerruti, C. , Fleckenstein, A. , Carroll, F. I. , Kuhar, M. J. , and Patel, A. P. Turnover of the Dopamine Transporter Protein in rDAT-LLC-PK1 Cells: Use of an Irreversible Ligand (RTI-76) and Antisense Oligonuclotides.  Neurosci.  Abstr.  21(1): 376, 1995.
  209. Fleckenstein, A. E. , Carroll, F. I. , Pögün, S. , and Kuhar, M. J. Recovery of Dopamine Transporter Binding and Function following Administration of the Irreversible Inhibitor RTI-76.  Neurosci.  Abstr.  21(1): 376, 1995.
  210. Vaughan, R. A. , McCoy, M. T. , and Kuhar, M. J. Localization of Dopamine Transporter Ligand Binding Domains to Transmembrane Segments.  Neurosci.  Abstr.  21(1): 376, 1995.
  211. Kopajtic, T. A. , McBurney, D. , Boja, J. W. , Carroll, F. I. , Kuhar, M. J. , and Schechter, M. D. Potent Phenyltropane Analogs of Cocaine Provide Strong Cue Strength and Long Cue Duration in the Drug Discrimination Task.  Neurosci.  Abstr.  21(1): 711, 1995.
  212. Kuhar, M. J. , Kopajtic, T. A. , Carroll, F. I. , Boja, J. W. , and Fleckenstein A. E. Highly Potent Cocaine Analogs Cause Long-Lasting Increases in Locomotor Activity.  Neurosci.  Abstr.  21(1): 757, 1995.
  213. Pilotte, N. S. , Sharpe, L. G. , Rountree, S. D. , and Kuhar, M. J. Cocaine Withdrawal Reduces Dopamine Transporter Binding in the Shell of the Nucleus Accumbens.  Neurosci.  Abstr.  21(1): 757, 1995.
  214. Patel, A. P. , Martel, J. C. , Vandenbergh, D. J. , Uhl, G. R. , and Kuhar, M. J. Cell Lines Expressing Human and Rat Dopamine Transporter cDNAs: Different Ligands Yield Different Radiolabeling Patterns.  Neurosci.  Abstr.  21(1): 781, 1995.
  215. Huff, R. A. , Vaughan, R. A. , Kuhar, M. J. , and Uhl, G. Protein Kinase Activity Modulates Dopamine Transporter Function.  Neurosci.  Abstr.  21(2): 1380, 1995.
  216. McCoy, M. T. , Brown, V. L. , Vaughan, R. A. , and Kuhar, M. J. Species-and Brain-Region Specific Dopamine Transporters: Immunological and Glycosylation Characterization.  Neurosci.  Abstr.  21(2): 1380, 1995.
  217. Couceyro, P. , Shoaib, M. , McCoy, M. , Goldberg, S. , and Kuhar, M. J. Characterization of a Novel Cocaine and Amphetamine Regulated Transcript (CART).  Neurosci.  Abstr.  21(3): 1951, 1995.
  218. Keverline, K. I. , Kopajtic, T. A. , Boja, J. W. , Kuhar, M. J. , Abraham, P. , Lewin, A. H. , and Carroll, F. I. Synthesis and Ligand Binding of Rigid Analogs of Paroxetine. NIDA Research Monograph Series No.    Problems of Drug Dependence 1995: Proceedings of the 57th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  228, 1996.
  219. Houlihan, W. J. , Boja, J. W. , Kuhar, M. J. , Kopajtic, T. A. , and Parrino, V. A. Maxindol Analogs as Potential Inhibitors of the Cocaine Binding Site. Structure Activity Relationiships.  NIDA Research Monograph Series No.    Problems of Drug Dependence 1995: Proceedings of the 57th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  229, 1996.
  220. Wong, D. F. , Naidu, S. , Yokoi, F. , Grunder, G. , Szymanski, S. , Dannals, R. F. , Ravert, H. , Kuhar, M. , Gjedde, A. , and Moser. H. In vivo Imaging of Pre- and Postsynaptic Dopamine Receptors in Rett Syndrome.  Neurosci.  Abstr.  22: 23, 1996.
  221. Nirenberg, M. J. , Vaughan, R. A. , Uhl, G. R. , Kuhar, M. J. , and Pickel, V. M. The Cocaine-Sensitive Dopamine Transporter: Ultrastructural Immunogold Localization in Mesolimbic Dopaminergic Neurons.  Neurosci.  Abstr.  22: 1786, 1996.
  222. Koylu, E. , Couceyro, P. , and Kuhar, M. J. Cocaine and Amphetamine Regulated Transcript (CART) Localization in Some Neurons and Neuroendocrine Cells.  Neurosci.  Abstr.  22: 1881, 1996.
  223. Couceyro, P. , Shoaib, M. , McCoy, M. , Goldberg, S. , and Kuhar, M. J. Cocaine Self-administration Alters Brain Gene Expression: Characterization of Differentially Regulated cDNAs.  Neurosci.  Abstr.  22: 1882, 1996.
  224. Ding, Y. -S. , Gatley, S. J. , Fowler, J. S. , Volkow, N. D. , Aggarwal, D. , Logan, J. , Dewey, S. L. , Liang, F. , Carroll, F. I. , and Kuhar, M. J. Mapping Nicotinic Acetylcholine Receptors (nAChR) with PET.  Neurosci.  Abstr.  22: 269, 1996.
  225. Patel, A. P. , Kopajtic, T. A. , and Kuhar, M. J. Chemical Modification of Dopamine Transporter (DAT): Role of Histidine Residues in Cocaine Analog Binding.  Neurosci.  Abstr.  22: 368, 1996.
  226. Kopajtic, T. , Scheffel, U. , Lever, J. , Abraham, P. , Parham, K. , Mathews, W. B. , Carroll, F. I. and Kuhar, M. J. Dopamine Transporter (DAT) Ligands: N-Substituted Phenyltropanes (NSPTs) as Ligands for Rapid PET/SPECT Studies.    Neurosci.  Abstr.  22: 369, 1996.
  227. Vaughan, R. A. , Huff, R. A. , Uhl, G. R. , and Kuhar, M. J. Phorbol Ester Induced Phosphorylation of Dopa¬mine Transporters in Rat Striatum.  Neurosci.  Abstr.  22: 509, 1996.
  228. Huff, R. A. , Vaughan, R. A. , Kuhar, M. J. and Uhl, G. R. Enhancement of Dopamine Transporter Phosphorylation by Phorbol Esters: Parallels with Phorbol-Induced Decreases in Transport.    Neurosci.  Abstr.  22: 510, 1996.
  229. Ding, Y. S. , Fowler, J. S. , Brady, D. , Gatley, S. J. , Volkow, N. D. , Dewey, S. L. , Liang, F. , Kuhar, M. J. , and Carroll, F. I. [18F]Norchloro-2-fluoroepibatidine Studies of Nicotine Acetylcholine Receptors (nAChR) in Living Primate and Postmortem Human Brain.  Neurosci.  Abstr.  23: 382, 1997.
  230. Smith, Y. , Paré, J. -F. , Koylu, E. , Couceyro, P. , Ince, E. , Levey, A. I. , and Kuhar, M. J. CART Peptide Immunoreactivity in the Nucleus Accumbens of Monkeys: Electron Microscopic Analysis and Co-localization Studies.  Neurosci.  Abstr.  23(1): 966, 1997.
  231. Lambert, P. D. , Couceyro P. R. , Koylu, E. O. , Ling, N. C. , DeSouza, E. B. , and Kuhar, M. J. CART Peptides have a Physiological Role in the Central Control of Food Intake.  Neurosci.  Abstr.  23(1): 966, 1997.
  232. Koylu, E. , Couceyro, P. , Lambert, P. , McGirr, K. , and Kuhar, M. J. CART Peptide Immunohisto¬chemistry in rat.  Neurosci.  Abstr.  23(1): 966, 1997.
  233. Couceyro, P. R. , Lambert, P. D. , Koylu, E. O. , Ling, N. C. , DeSouza, E. B. , and Kuhar, M. J. CART Peptides have a Role in Cocaine-Induced Locomotor Activity.  Neurosci.  Abstr.  23(1): 966, 1997.
  234. McGirr, K. , Kopajtic, T. , Dworkin, S. , Howell, L. , Carroll, F. I. , Hunter, R. , and Kuhar, M. J. Cocaine Pharmacotherapy with RTI-113.  Neurosci.  Abstr.  23(2): 1102, 1997.
  235. Garrett, B. E. , McGirr, K. , Hunter, R. , Carroll, F. I. , and Kuhar, M. J. Cocaine Analog Characterization at Neurotransmitter Transporters.  Neurosci.  Abstr.  23(2): 1102, 1997.
  236. Lévesque, D. , D’Antoni, T. J. , Kuhar, M. J. , and Greenamyre, J. T. Behavioral Effects of RTI-113, a Dopa¬mine Uptake Inhibitor, in MPTP-Treated Monkeys.  Neurosci.  Abstr.  23(2): 1896, 1997.
  237. Lambert, P. D. , Couceyro, P. R. , Koylu, E. O. , Ling, N. C. , DeSouza, E. B. , and Kuhar, M. J. A Role for Novel CART Peptide Fragments in the Central Control of Food Intake. Neuropeptides 31(6): 620-621, 1997.
  238. Kuhar, M. J. , Carroll, F. I. , Howell, L. , and Dworkin, S. Transporters and Medications Development. Symposium VII, Recent Progress in Transporter Research.  NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1997: Proceedings of the 59th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  33, 1998.
  239. Couceyro, P. , McGirr, K. , and Kuhar, M. J. Genetic Variation in Cocaine- and Amphetamine-Regulated Transcript (CART) Expression between Lewis (LEW) and Fischer (F344) Rats. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1997: Proceedings of the 59th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  83, 1998.
  240. Navarro, H. , Liang, F. , Ross, W. P. , Ding, Y. S. , Volkow, N. , Kuhar, M. J. , and Carroll, F. I. Synthesis and Nicotine Acetylcholine Receptor Binding Properties of Epibatidine Analogs, Potential PET and SPECT Ligands. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1997: Proceedings of the 59th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  157, 1998.
  241. Koylu, E. O. , Couceyro, P. R. , Lambert, P. D. , and Kuhar, M. J. CART Peptide Immunohistochemistry in the Rat. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1997: Proceedings of the 59th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  269, 1998.
  242. Lambert, P. D. , Couceyro, P. R. , Koylu, E. O. , Ling, N. C. , De Souza, E. B. , and Kuhar, M. J. Novel CART Peptides – A Psychostimulant-Like Behavioral Profile. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1997: Proceedings of the 59th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  270, 1998.
  243. Holmquist, C. , Keverline-Frantz, K. K. , Abraham, P. , Boja, J. W. , Kuhar, M. J. , and Carroll, F. I. Synthesis and Transporter Binding Properties of 3-(Substituted Phenyl)Tropane-2-Carboxylic Acid Esters. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1997: Proceedings of the 59th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  273, 1998.
  244. Kuhar, M. J. , Carroll, F. I. , Dworkin, S. , Howell, L. , Hunter, R. , and McGirr, K. Pharmacotherapy of Cocaine Abuse with RTI-113. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1997: Proceedings of the 59th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  278, 1998.
  245. Lambert, P. , Couceyro, P. , Koylu, E. , McGirr, K. and Kuhar, M. Central CART Peptides Inhibit Food Intake Via a Mechanism Involving Neuropeptide Y.  Neuropeptides 32(4): 378, 1998.
  246. Garras, P. A. , Wu, Q. , Reith, M. E. A. , Kuhar, M. J. , and Carroll, F. I. In vivo Effects of Cocaine in the Striatum: Analysis of d[DA]EC/dt.  Neurosci.  Abstr.  24(1): 609, 1998.
  247. Wu, Q. , Reith, M. E. A. , Kuhar, M. J. , Carroll, F. I. , and Garris, P. A. In vivo Effects of Cocaine in the Striatum: Changes in [DA]EC and d[DA]EC/dt.  Neurosci.  Abstr.  24(1): 609, 1998.
  248. Kimmel, H. L. , Vicentic, A. , Lambert, P. D. , Carroll, F. I. , and Kuhar, M. J. Dopamine Transporter Turnover, Synthesis and Degradation in Rat Brain.  Neurosci.  Abstr.  24(1): 611, 1998.
  249. Koylu, E. O. , Demirgoren, S. , Taskiran, D. , Kuhar, M. J. , and Pogun, S. In vivo Nitric Oxide Synthase (NOS) Inhibition Facilitates Glutamate Transport in Rats.  Neurosci.  Abstr.  24(1): 775, 1998.
  250. Vicentic, A. , Carroll, F. I. , Battaglia, G. , and Kuhar, M. J. Serotonin Transporter (SERT) Production and Degradation: Studies with RTI-76.  Neurosci.  Abstr.  24(1): 1115, 1998.
  251. Czoty, P. W. , Kuhar, M. J. , Carroll, F. I. , and Howell, L. L. Behavioral Pharmacology of the Selective Dopamine Uptake Inhibitor, RTI-113, in the Squirrel Monkey.  Neurosci.  Abstr.  24(2): 1484, 1998.
  252. Grace, A. A. , Kuhar, M. J. , Lambert, P. D. , Couceyro, P. R. , and Onn, S. -P. Both Amphetamine and CART Peptide Suppress Prefrontal Corticoaccumbens Synaptic Transmission.  Neurosci.  Abstr.  24(2): 1644, 1998.
  253. Ding, Y. -S. , Fowler, J. S. , Volkow, N. D. , Logan, J. , Dewey, S. L. , Kuhar, M. J. , and Carroll, F. I. Modulation of Dopamine D2 Receptor on Striatal Cholinergic Activity: PET Studies with [18F]Fluoro¬epibatidine.  Neurosci.  Abstr.  24(2): 1760, 1998.
  254. Kuhar, M. J. and Couceyro, P. R. CART Gene Knockout: Construction of a Target Vector.    Neurosci.  Abstr.  24(2): 2042, 1998.
  255. Couceyro, P. R and Kuhar, M. J. Identification of Processed CART Peptide Fragments in Rat Brain by Western Blotting.  Neurosci.  Abstr.  24(2): 2042, 1998.
  256. Dall Vechia, S. E. , Paré, J. -F. , Lambert, P. , Couceyro, P. Kuhar, M. , and Smith, Y. Synaptic Interactions between CART Peptide-Immunoreactive Terminals and Midbrain Dopaminergic Neurons in the Rat.    Neurosci.  Abstr.  24(2): 2043, 1998.
  257. Paré, J. -F. , Dall Vechia, S. E. , Lambert, P. Couceyro, P. Garrett, B. E. , Kuhar, M. , and Smith, Y.  CART Peptide-Immunoreactive Neurons in the Monkey PVN: Electron Microscopic Characterization and Synaptic Relationships with NPY-Immunoreactive Terminals.    Neurosci.  Abstr.  24(2): 2043, 1998.
  258. McGirr, K. M. , Couceyro, P. R. , and Kuhar, M. J. Evidence that Endogenous CART Peptides Regulate Corticosterone Levels.  Neurosci.  Abstr.  24(2): 2043, 1998.
  259. Kimmel, H. L. , Garrett, B. E. , Carroll, F. I. , and Kuhar, M. J. Characterization of the Locomotor Effects of Novel Cocaine Analogs.  Neurosci.  Abstr.  25(1): 306, 1999.
  260. Elias, C. F. , Kelly, J. F. , Lee, C. , Drucker, D. J. , Kuhar, M. J. , Saper, C. B. , and Elmquist, J. K. Leftin Activates Neurons Containing Anorectic Peptides in the Rat Brain.  Neurosci.  Abstr.  25(1): 621, 1999.
  261. Vicentic, A. , Kuhar, M. J. , and Battaglia, G. Initial Determination of 5-HT Transporter Turnover in Dorsal versus Median Raphe Nuclei: Regional and Maturational Differences.  Neurosci.  Abstr.  25(2): 1701, 1999.
  262. Battaglia, G. , Vicentic, A. , and Kuhar, M. J. Determination of 5-HT Transporter Turnover Kinetics in 5-HT Terminal Fields: Effects of Maturation.  Neurosci.  Abstr.  25(2): 1701, 1999.
  263. Broberger, C. , Holmberg, K. , Kuhar, M. J. , and Hökfelt, T. Cocaine- and Amphetamine-Regulated Transcript (CART) in Rat Nodose and Dorsal Root Ganglia: A Putative Mediator of Cholecystokinin-(CCK-) Induced Satiety.  Neurosci.  Abstr.  25(2): 2219, 1999.
  264. Dall Vechia, S. , Gong, W. , Smith, Y. , and Kuhar, M. Selective Excitotoxic Lesions of the Nucleus Accumbens in Rats: Differential Effects on CART Peptide-ir Varicosities in the Ventral Midbrain.  Neurosci.  Abstr.  25(2): 2220, 1999.
  265. Adams, L. D. , Yoho, L. L. , and Kuhar, M. J. Chromosomal Localization and Characterization of the Mouse Genomic DNA Encoding CART Peptide(s).  Neurosci.  Abstr.  25(2): 2226, 1999.
  266. Kuhar, M. J. , Yoho, L. , Hunter, R. , Gong, W. , Ghatei, M. , and Bloom, S. CART Peptide Analysis by Western Blotting and RIA.  Neurosci.  Abstr.  25(2): 2226, 1999.
  267. Kuhar, M. J. Phenyltropanes as Substitute Agonists for Cocaine Abuse. Symposium XI, “Agonist”-Type Approaches to the Treatment of Cocaine Dependence”.  NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1998: Proceedings of the 60th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  37, 1999.
  268. Couceyro, P. R. and Kuhar M. J. Identification of C-Terminal Peptides from Cocaine- and Amphetamine-Regulated Transcript (CART) in Sprague-Dawley Rats and Evidence for Peptide Processing.  NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1998: Proceedings of the 60th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  178, 1999.
  269. Dall Vechia, S. E. , Paré, J. -F. , Lambert, P. , Couceyro, P. , Kuhar, M. , and Smith, Y. CART Peptide Immuno-reactivity in the Hypothalamic PVN in Monkeys: Distributio and Interactions with NPY. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1998: Proceedings of the 60th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  179, 1999.
  270. Kimmel, H. L. , Vicentic, A. , Lambert, P. D. , Kuhar, M. J. , and Carroll, F. I. Turnover of Dopamine Transporters in Rat Brain. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1998: Proceedings of the 60th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  183, 1999.
  271. Vicentic, A. , Carroll, F. I. , Bhattaglia, G. , and Kuhar, M. J. Serotonin Transporter Production and Degrada¬tion: Studies with RTI-76. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1998: Proceedings of the 60th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  184, 1999.
  272. Garrett, B. E. , Carroll, F. I. , and Kuhar, M. J. Evaluation of the Psychomotor Stimulant Effects of Potential Medications for Cocaine Abusers. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1998: Proceedings of the 60th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  292, 1999.
  273. Deutsch, H. M. , Collard, D. L. , Zhang, L. , Burnham, K. , Javanmard, S. , Deshpande, A. , Holtzman, S. G. , Kuhar, M. J. , and Schweri, M. M. 3-Phenyl-2-amino(methyl)-bicyclo [2. 2. 2] and [2. 2. 1]-alkanes Dopamine Uptake Inhibitors. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1999: Proceedings of the 61st Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  71, 2000.
  274. Dall Vechia, S. E. , Smith, Y. , and Kuhar, M. Excitotoxic Lesions of the Nucleus Accumbens: Effect on CARTir Varicosities in the Midbrain. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1999: Proceedings of the 61st Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  214, 2000.
  275. Vicentic, A. , Kuhar, M. J. , Carroll, F. I. , and Battaglia, G. Autoradiographic Determination of Regional Differences in 5-HT Transporter (SERT) Inactivation by RTI-76. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1999: Proceedings of the 61st Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  250, 2000.
  276. Blough, B. E. , Boja, J. W. , Kuhar, M. J. , and Carroll, F. I. Tethered Biphenyl WIN 35,065-2 Analogs: Evidence of a Remote Lipophillic Binding Site on the Dopamine Transporter. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1999: Proceedings of the 61st Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  255, 2000.
  277. Kimmel, H. L. , Payne, S. C. , Carroll, F. I. , and Kuhar, M. J. Dopamine Transporter Synthesis and Degradation Rate in Rat Striatum and Nucleus Accumbens after Withdrawal from Cocaine. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1999: Proceedings of the 61st Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  256, 2000.
  278. Gong, W. , Vechia, S. D. , Hunter, R. , and Kuhar, M. J. CART Peptide 55-102 Induces Psychostimulant-Like Behavioral Effects. NIDA Research Mono¬graph Series No.    Problems of Drug Dependence 1999: Proceedings of the 61st Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc. , p.  292, 2000.
  279. Dall Vechia Adams, S. , Smith, Y. , and Kuhar, M. J. Anatomical Characterizstion of CART Peptides in the Nucleus Accumbens and Ventral Midbrain: Functional Implications. [Abstracts from the 62nd Annual Scientific Meeting, The College on Problems of Drug Dependence, June 17-22, 2000, San Juan, Puerto Rico] Drug Alcohol Depend. , 60(Suppl 1): S3, 2000.
  280. Howell, L. L. , Kimmel, H. L. , O’Connor, J. A. , Carroll, F. I. , and Kuhar, M. J. Effects of the Selective Dopamine Reuptake Inhibitor, RTI-112, on Operant Behavior in the Squirrel Monkey. [Abstracts from the 62nd Annual Scientific Meeting, The College on Problems of Drug Dependence, June 17-22, 2000, San Juan, Puerto Rico] Drug Alcohol Depend.  60(Suppl.  1): S94, 2000.
  281. Hunter, R. G. , Kuhar, M. J. , Damaj, I. , and Martin, B. R. CART Peptides have Analgesic Properties. [Abstracts from the 62nd Annual Scientific Meeting, The College on Problems of Drug Dependence, June 17-22, 2000, San Juan, Puerto Rico] Drug Alcohol Depend.  60(Suppl.  1): S96, 2000.
  282. Javanmard, S. , Deutsch, H. M. , Collard, D. M. , Kuhar, M. J. , and Schweri, M. M. Synthesis and Pharmacology of Dopamine Uptake Inhibitors: 2-substituted-6-amino-5-phenylbicyclo[2. 2. 2]octanes. [Abstracts from the 62nd Annual Scientific Meeting, The College on Problems of Drug Dependence, June 17-22, 2000, San Juan, Puerto Rico] Drug Alcohol Depend.  60(Suppl.  1): S99, 2000.
  283. Joyce, A. R. , Kimmel, H. L. , Carroll, F. I. , and Kuhar, M. J. Dopamine Receptor Agonists and Antagonists Alter DAT Turnover in the Striatum and Nucleus Accumbens of the Rat. [Abstracts from the 62nd Annual Scientific Meeting, The College on Problems of Drug Dependence, June 17-22, 2000, San Juan, Puerto Rico] Drug Alcohol Depend.  60(Suppl.  1): S103, 2000.
  284. Kimmel, H. L. , Gong, W. , and Kuhar, M. J. CART Peptides have Psychostimulant-Like Effects in the Rat. [Abstracts from the 62nd Annual Scientific Meeting, The College on Problems of Drug Dependence, June 17-22, 2000, San Juan, Puerto Rico] Drug Alcohol Depend.  60(Suppl.  1): S112, 2000.
  285. Adams, S. D. , Kuhar, M. J. , and Smith, Y. CART Peptides’ Role in Psychomotor Stimulant-Like Behavioral Effects: Anatomical Substrates.  Neurosci.  Abstr.  26(1): 27, 2000.
  286. Kimmel, H. L. and Kuhar, M. J. Cocaine- and Amphetamine-Regulated Peptides Produce Psychostimulant-Like Effects in the Rat.    Neurosci.  Abstr.  26(1): 526, 2000.
  287. Onn, S. -P. , Kuhar, M. J. , and Grace, A. A. Prefrontal Cortical-Accumbens Transmission is Potently Regulated by Multiple Neuromodulatory Systems. Socl Neurosci.    26(1): 961, 2000.
  288. Broberger, C. , Kuhar, M. J. , and Hökfelt, T. Cocaine- and Amphetamine-Regulated Transcript (CART) in the Pituitary: Regulation and Coexistence with Prolactin.  Neurosci.  Abstr.  26(1): 1175, 2000.
  289. Ebbesson, L. O. E. , Ekström, P. , Ebbesson, S. O. E. , Hansen, T. , Yoho, L. L. , and Kuhar, M. J. CART Immuno-reactivity in the Salmon Brain: Distribution and Relation to NPY.  Neurosci.  Abstr. .  26(2): 1927, 2000.
  290. DallVechia-Adams, S. , Kuhar, M. J. , and Smith, Y. Anatomical Basis of CART Peptides’ Psychostimulant-Like Behavioral Effects. [Abstracts from the 63rd Annual Scientific Meeting, The College on Problems of Drug Dependence, June 16-21, 2001, Scottsdale, AZ] Drug Alcohol Depend.  63(Suppl.  1): S37, 2001.
  291. Joyce, A. R. and Kuhar, M. J. Slow Onset of Addicting Drugs: Can Canges in Levels of Proteins Account for the Delay? [Abstracts from the 63rd Annual Scientific Meeting, The College on Problems of Drug Depen¬dence, June 16-21, 2001, Scottsdale, AZ] Drug Alcohol Depend.  63(Suppl.  1): S75, 2001.
  292. Kimmel, H. L. , Thim, L. , and Kuhar, M. J. Varioius CART Peptides Produce Locomotor Activity in the Rat. [Abstracts from the 63rd Annual Scientific Meeting, The College on Problems of Drug Depen¬dence, June 16-21, 2001, Scottsdale, AZ] Drug Alcohol Depend.  63(Suppl.  1): S81, 2001.
  293. Navarro, H. A. , Xul, H. , Zhong, D. , Blough, B. E. , Ross, W. P. , Kuhar, M. J. , and Carroll, F. I. Pharmacological Characterization of [125]3beta (4-ethyl-3-iodophenyl) nortropane-2beta-carboxylic acid methyl ester. [Abstracts from the 63rd Annual Scientific Meeting, The College on Problems of Drug Depen¬dence, June 16-21, 2001, Scottsdale, AZ] Drug Alcohol Depend.  63(Suppl.  1): S113, 2001.
  294. Kimmel, H. L. , Thim, L. , and Kuhar, M. J. Intra-VTA Administration of CART Peptides Increase Locomotor Activity in the Rat.  Neurosci.  Abstr.  27: No.  30. 16, 2001.
  295. Jaworski, J. , Joyce, A. R. , and Kuhar, M. J. Therapeutic Delay: Can Synthesis of New Proteins be a Cause? Soc.  Abstr.  27: No.  220. 1, 2001.
  296. Kuhar, M. J. , and Joyce, A. R. A Model for Time Courses of Levels of Sequentially Produced Proteins.  Neurosci.  Abstr.  27: No.  220. 2, 2001.
  297. Adams, S. D. , Kuhar, NM. J. , and Smith, Y. CART Peptide Immunoreactive Terminals in the Ventral Midbrain: Synaptic Connectivity with Dopaminergic Neurons and Neurochemical Characterization.  Neurosci.  Abstr.  27: No.  239. 8, 2001.
  298. Hunter, R. G. , Lakatos, A. , Dominguez, G. , and Kuhar, M. J. CART Gene Promoter Characterization.  Neurosci.  Abstr.  27: No.  246. 12, 2001.
  299. Balkan, B. , Koylu, E. O. , Kuhar, M. J. , and Pogun, S. The Effect of Adrenalectomy on Cocaine and Amphetamine Regulated Transcript (CART) Expression in the Hypothalamic Nuclei of the Rat.  Neurosci.  Abstr.  27: No.  735. 6, 2001.
  300. Hunter, R. G. and Kuhar, M. J. CART mRNA Regulation by Dopamine in the Rat Nucleus Accumbens.  Program No.   9.  2002 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2002.  Online.
  301. Kuhar, M. J. , Kimmel, H. L. , Joyce, A. R. , and Carroll, F. I. Dopamine Transporter Protein Synthesis and Degradation in Rat Striatum and Nucleus Accumbens. Program No.   1.  2002 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2002.  Online.
  302. Balkan, B. , Koylu, E. , Kuhar, M. J. , and Pogun, S. CART Involvement in HPA Axis and Stress. Program No.   8.  2002 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2002.  Online.
  303. Muly, E. C. , Maddox M. , Kuhar, M. J. , and Smith, Y. Localization of Group I Metabotropic Glutamate Receptors (MGLURS) in Primate Prefrontal Cortex (PFC). Program No.   13.  2002 Abstract Viewer/ Itinerary Planner.  Society for Neuroscience, Washington, DC, 2002.  Online.
  304. Lakatos, A. , Dominguez, G. , and Kuhar, M. J. CREB Regulation of the CART Gene in GH3 Cells. Program No.   6.  2002 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2002.  Online.
  305. Jaworski, J. N. , Kozel, M. A. , and Kuhar, M. J. CART Injection into Nucleus Accumbens Reduces Cocaine-Induced Locomotion in Rats. Program No.   12.  2002 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2002.  Online.
  306. Dominguez, G. and Kuhar, M. J. CART Processing in GH3 and CATH. a cells.  Neuropeptides 37(3): 179, 2003.
  307. Wierup, N. , Kuhar, M. J. , Ekblad, E. , and Sundler, F. B-Cell Exression of Cocaine- and Amphetamine-Regulated Transcript (CART) in Rat Type 2 Diabetes Models. Diabetes & Metab.  29: 4S7-4S428, 2003.
  308. Kuhar, M. J. and Dominguez, G. CART Promoter CRE Site Confers Responsiveness to Cyclic AMP in CATH. a Cells.  Program No.   14.  2003 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2003.  Online.
  309. Hunter, R. G. and Kuhar, M. J. Dopaminergic Regulation of CART Gene Expression in the Rat Nucleus Accumbens.  Program No.   21.  2003 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2003.  Online.
  310. Jaworski, J. N. and Kuhar, M. J. CART Peptides: Suspected Modulators of Mesolimbic Dopamine.  Program No.   2.  2003 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2003.  Online
  311. Vicentic, A. , Dominguez, G. , Hunter, R. , Philpot, K. , and Kuhar, M. J. CART Peptide Levels in Blood Exhibit Diurnal Rhythm. Program No.   20.  2003 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2003.  Online.
  312. Philpot, K. B. , Hunter, R. G. , Lim, M. M. , Young, L. J. , and Kuhar, M. J. Differential CART mRNA Expression between Prairie and Meadow Voles: A Role in Pair Bonding? Program No. 4.  2003 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2003.  Online.
  313. Dominguez, G. and Kuhar, M. J. Mutated CART Gene Results in Altered Processing of proCART.  Program No.   9.  2003 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2003.  Online.
  314. Hunter, R. G. , Jaworski, N. J. , Dominguez, G. , and Kuhar, M. J. CART Peptides in Drug Abuse and Dependence. 4th ECNP Workshop 2003: Neuropsychopharmacology of Addiction, Nice, France, March 2003.  European Neuropsychopharmacology 13(1), 2003.
  315. Jaworski, J. N. and Kuhar, M. J. Cocaine’s Locomotor Effects are Antagonized by Intra-accumbal CART Peptides.  Proceedings of the 65th Annual Meeting of the College on Problems of Drug Dependence, Bal Harbour, FL, 2003.
  316. Jaworski, N. J. and Kuhar, M. J. Intra-accumbal CART Peptide Inhibits Locomotor Activity Induced by Both (i. p. ) Cocaine and Intra-accumbal Dopamine.    Soc.  Pharmacol.  Exp.  Ther.  Abstract, #83028, 2003.
  317. Philpot, K. , Vicentic, A. , Hunter, R. G. , Lim, M. , KUhar, M. J. , and Young, L. CART Peptide: The Third Neurophysiological Hormone? Neurohypophysial Hormone Meeting, Kyoto Japan, 2003.
  318. Vicentic, A. , Dominguez, G. , Hunter, R. , and Kuhar, M. CART Peptide Levels in Blood Exhibit a Circadian Rhythm. Experimental Biology Annual Meeting, ASPET, San Diego, CA, 2003.
  319. Vicentic, A. , Dominguez, G. , Hunter, R. , and Kuhar, M. J. Diurnal Rhythm of CART Peptide in Rat Blood. Experimental Biology Annual Meeting, ASPET, San Diego, CA, 2003.
  320. Hunter, R. G. and Kuhar, M. J. CART mRNA in the Rat Nucleus Accumbens is Down-Regulated via D3 Dopa-mine Receptors.  Program, Experimental Biology 2004, ASPET, Washington, DC, Abstract #162. 11, 2004.
  321. Vicentic, A. , Hunter, R. G. , Philpot, K. , Dominguez, G. , and Kuhar, M. J. CART Peptide Levels in the Brain Exhibit a Diurnal Rhythm and are Influenced by Fasting. Program, Experimental Biology 2004, ASPET, Washington, DC, Abstract #394. 2, p.  153, 2004.
  322. Hunter, R. G. and Kuhar, M. J. CART mRNA Expression is Regulated by D3 Receptors in the Rat Nucleus Accumbens.  66th Annual Meeting of the College on Problems of Drug Dependence, San Juan, PR, June, 2004.  CPDD 2004 Abstracts and Program.
  323. Jaworski, J. N. , Kimmel, H. L. , Mitrano, D. A. , Tallarida, R. J. , and Kuhar, M. J. CART 55-102 Reduces the Locomotor Activating Effects of Cocaine: An Isobolographic Analysis. 66th Annual Meeting of the College on Problems of Drug Dependence, San Juan, PR, June, 2004.  CPDD 2004 Abstracts and Program.
  324. Zurich, K. J. , Francis, D. D. , Kuhar, M. J. , and Jaworski, J. N. Ethanol Preference in Rats after Variations in Maternal Separation. 66th Annual Meeting of the College on Problems of Drug Dependence, San Juan, PR, June, 2004.  CPDD 2004 Abstracts and Program.
  325. Francis, D. D. and Kuhar, M. J. Early Life Maternal Separation in Rodents: What about Moms? 66th Annual Meeting of the College on Problems of Drug Dependence, San Juan, PR, June, 2004.  CPDD 2004 Abstracts and Program.
  326. Balkan, B. , Gozen, O. , Yararbas, G. , Koylu, E. , Kuhar, M. J. , and Pogun, S. Sex Differences in the Modulation of Cocaine and Amphetamine-Regulated Transcript Expression in the Arcuate and Paraventricular Nuclei of the Rat. 66th Annual Meeting of the College on Problems of Drug Dependence, San Juan, PR, June, 2004.  CPDD 2004 Abstracts and Program.
  327. Yanik, T. , Dominguez, G. , Kuhar, M. J. , and Loh, Y. P. Mutant Leu34Phe Pro-CART in Obese Humans is Missorted, Poorly Processed and Constituvely Secreted in Endocrine Cells. Presented at ENDO 2004, Annual Meeeting of the Endocrine Society, June, 2004, New Orleans, LA.
  328. Yanik, T. , Dominguez, G. , Kuhar, M. J. , and Loh, Y. P. Missense Mutations at Pro-CART in Obesed Humans is Missorted, Poorly Processed and Constitutively Secreted in Endocrine Cells. Neuropeptides, 39: 65, 2005.
  329. Balkan, B. , Gozen, O. , Yararbas, G. , Koylu, E. O. , Kuhar, M. J. , and Pogun, S. Sex Differences in the Modulation of CART Expression in Hypothalamic Nuclei of Rats by Stress.  No.  193. 6.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.  Online.
  330. Philpot, K. B. , Dallvechia-Adams, S. , Smith, Y. , and Kuhar, M. J. The Food Connection: Charaterization of the Synaptic Connectivity of CART-Immunoreactive Neurons in the Lateral Hypothalamus/Perifornical Area in the Rat. Program No.   11.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.  Online.
  331. Jaworski, J. N. , Francis, D. D. , and Kuhar, M. J. Variations in Maternal Separation Affect Ethanol Intake in Adult Rats. Program No.   2.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.  Online.
  332. Hubert, G. W. and Kuhar, M. J. Colocalization of Cocaine and Amphetamine-Regulated Trnscript (CART) with Subsance P in the Nuceleus Accumbens (NACC) of Rats.  Program No.   11.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.  Online.
  333. Lakatos, A. , Vicentic, A. , Prinster, S. , Hall, R. A. , and Kuhar, M. J. CART Receptor is Coupled to GI/O Protei and Map Kinase Activood Program No. 12.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.
  334. Hunter, R. G. and Kuhar, M. J. Chronic Manipulations of the Dopamine System Affects CART mRNA Expression in the Nucleus Accumbens of the Rat.  Program No.   8.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.  Online.
  335. Francis, D. D. and Kuhar, M. Variations in Maternal Separation Protocols and Adult Open-Field Activity in the Rat.  Program No.   8.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.  Online.
  336. Dominguez, G. , Hon, H. , Hunter, R. G. , Francis, D. D. , and Kuhar, M. J. Variations in Maternal Separation Protocols and Cytokine Profiles in the Rat. Program No.   24.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.  Online.
  337. Vicentic, A. , Dominguez, G. , Rye, D. , and Kuhar, M. CART Peptide Identification in Monkey and Human CSF. Program No.   6.  2004 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2004.  Online.
  338. Jones, D. C. and Kuhar, M. J. CART Expression in the Rat Nucleus Accumbens is Regulated by the PKA/ CREB Pathway.  Program, Experimental Biology 2005, ASPET, San Diego, CA, Abstract #310. 4, 2005.
  339. Lakatos, A. , Vicentic, A. , Hall, R. A. , Prinster, S. , and Kuhar, M. J. CART Receptor is Coupled to Gi/o and MAP Kinase Activation in AtT20 Cells. Program, Experimental Biology 2005, ASPET, San Diego, CA, Abstract #876. 9, 2005.
  340. Vicentic, A. , Domnguez, G. , Rye, D. , and Kuhar, M. CART Peptide Identification in Monkey and Human CSF. Program, Experimental Biology 2005, ASPET, San Diego, CA, Abstract #310. 5, 2005.
  341. Keating, G. L. , Kuhar, . J. , Vicentic, A. , and Rye, D. B. Wake Promotion and Seizure Activity following I. C. V. CART Peptide in the Rat.  Program No.   14.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  342. Koylu, E. O. , Balkan, B. , Gozen, O. , Yararbas, G. Y. , Kuhar, M. J. , and Pogun, S. The Modulation of Cocaine and Amphetamine Regulated Transcript (CART) Levels in Hypothalamus, Amygdala, and Hippocampus of Rat Brain following Forced-Swim Stress. Program No.   9.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  343. Kuhar, M. J. , Vicentic, A. , Lakatos, A. , Francis, D. , Hurley, J. , and Moffett, M. Maternal Separation Alters 5-HT Transporter and 5-HT1A Receptor Densities. Program No.   6.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  344. Lakatos, A. , Douglas, J. C. , Rogge, G. A. , Vicentic, A. , and Kuhar, M. J. Cocaine- and Amphetamine-Regulated Transcript (CART) Gene is Regulated by Elevated Intracellular Calcium in vitro and in vivo. Program No.   18.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  345. Moffett, M. C. and Kuhar, M. J. Early Maternal Separation Affect Cocaine Self-administration in Dams.  Program No.   19.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  346. Jones, D. C. and Kuhar, M. J. CART Expression in the Rat Nucleus Accumbens is Regulated via cAMP/PKA/ CREB Signaling.  Program No.   13 2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  347. Rogge, G. A. , Jones, D. C. , Vicentic, A. , and Kuhar, M. J. Regulation of CART Expression by CIS-Regulatory Elements in the CART Promotor. Program No.   21.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  348. Harley, J. L. , Moffett, M. M. , Hsiung, H. M. , Asnicar, M. A. , and Kuhar, M. CART Knock-Out Mice Vary in Response to Cocaine and a Novel Environment. Program No.   15.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  349. Vicentic, A. , Rye, D. , and Kuhar, M. J. Identification of CART in Cerebrospinal Fluid: Measurement in Human Neurological Disorders. Program No.   13.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  350. Hubert, G. W. and Kuhar, M. J. Colocalization of Cocaine and Amphetamine-Regulated Transcript (CART) with Dopamine D1 Receptors and Activation of CART Cells by Cocaine in the Nucleus Accumens (NAcc) of Rats.  Program No.   9.  2005 Abstract Viewer/Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  351. Gysling, K. , Blanco, E. , and Kuhar, M. J. Acute Morphine Treatment Decreases Urocortin and CART Peptide Immunoreactivity in the Rat Edinger Westphal Nucleus. Program No.   16.  2005 Abstract Viewer/ Itinerary Planner.  Society for Neuroscience, Washington, DC, 2005.  Online.
  352. Hubert, G. W. and Kuhar, M. J. Colocalization of Cocaine- and Amphetamine-Regulated Transcript (CART) with Dynorphin in the Nucleus Accumbens (NAcc) of Rats.  Program No.   3.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  353. Jaworski, J. N. , Hansen, S. T. , Kuhar, M. J. , and Mark G. P. Intra-accumbal Injection of Cocaine- and Amphetamine-Regulated Transcript Peptide Alters Cocaine Self-administration. Program No.   9.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  354. Tunaru, S. , Vicentic, A. , Hubert, G. W. , Kuhar, M. J. , and Hall R. A. Cross-Linking of Cocaine- and Amphetamine-Regulated Transcript (CART) to AtT20 Cells: A Biochemical Approach to Isolate and Identify the CART Receptor. Program No.   2.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  355. Stanek, L. , Moffett, M. , and Kuhar, M. J. Creation of a Lenti Viral Vector to Overexpress Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide. Program No.   1.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  356. Manvich, D. F. , Hubert, G. W. , and Kuhar, M. J. Distributions of CART Peptide-Immunoreactive Axon Terminals Originating in the Nucleus Accumbens Shell. Program No.   5.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  357. Kuhar, M. J. , Philpot, K. B. , and Mitrano, D. CART mRNA Expression is Lower in Inbred Diet-Induced Obesity (DIO) Rat Compared to Diet-Resistant (DR) Rats Regardless of Diet. Program No.   10.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  358. Sundler, F. E. , Bjorkqvist, M. , Mulder, H. , Kuhar, M. J. , and Wierup, N. CART, a New Player in the Regulation of Islet Hormone Secretion. Program No.   6.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  359. Vicentic, A. , Hall, R. A. , Lakatos, A. , and Kuhar, M. CART Peptide Receptors: Specific Binding and GTP Effect. Program No.   7.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  360. Rogge, G. A. , Moffet, M. C. , and Kuhar, M. J. Binge Cocaine Administration Increases CREB Binding to the CART Gene CRE Cis-Regulatory Element in the Rat Nucleus Accmbens. Program No.   4.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  361. Koylu, E. O. , Erdogan, M. , Karadeniz, M. , Saygili, F. , Balkan, B. , Pogun, S. , and Kuhar, M. J. Plasma CART Peptide Levels in Thyroid Patients: Body Mass Index, Gender, and Age-Related Changes. Program No.   8.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  362. Moffett, M. and Kuhar, M. J. Preliminary Evidence of Transient Effects of Maternal Separation on Cocaine Self-administration in Dams.  Program No.   8.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  363. Jones, D. C. and Kuhar, M. J. Regulation of CART Gene Expression by CREB-Mediated Transcription; Effect of Cocaine.  Program No.   1.  2006 Neuroscience Meeting Planner.  Society for Neuroscience, Atlanta, GA, 2006.  Online.
  364. Jones, D. and Kuhar, M. J. CART Receptor Binding in Primary Cell Cultures of Nucleus Accumbens.  Program No.   1.  2007 Neuroscience Meeting Planner.  Society for Neuroscience, San Diego, CA, 2007.  Online.
  365. Moffett, M. C. and Kuhar, M. J. Modulatory Role of CART Peptide in the Nucleus Accumbens on Dopaminergic Function.  Program No.   8.  2007 Neuroscience Meeting Planner.  Society for Neuroscience, San Diego, CA, 2007.  Online.
  366. Rogge, G. A. , Moffett, M. , Jones, D. , and Kuhar, M. CART Gene Regulation, a Role for CREB. Program No.   23.  2007 Neuroscience Meeting Planner.  Society for Neuroscience, San Diego, CA, 2007.  Online.
  367. Hubert, G. W. and Kuhar, M. J. CART Peptide Projections Originating in the Nucleus Accumbens Shell Terminate in the Ventral Pallidum.  Program No.   11.  2007 Neuroscience Meeting Planner.  Society for Neuroscience, San Diego, CA, 2007.  Online.
  368. Baile, C. A. , Bartell, S. , Gaddam, D. R. , Ambati, S. , Rayalam, S. , Hartzell, D. L. , Hamrick, M. , She, J. -X. , Kuhar, M. and Della-Fera, M. Central leptin treatment mediation of bone marrow cell differentiation is enhanced when caloric restriction is imposed upon male mice.  Program No.   21.  2008 Neuroscience Meeting Planner.  Society for Neuroscience, Washington D. C. , 2008.  Online.
  369. Hubert, G. W. and Kuhar, M. J. Cocaine- and amphetamine-regulated transcript (CART) peptide injected into the ventral pallidum (VP) inhibits cocaine-induced locomotion.  Program 564. 25 2008 Neuroscience Meeting Planner.  Society for Neuroscience, Washington D. C. , 2008.
  370. Jones, D. C. and Kuhar, M. J. The effect of Bisphenol A on the rat dopamine system and cocaine-induced behaviors.  Program No.   11.  2008 Neuroscience Meeting Planner.  Society for Neuroscience, Washington D. C. , 2008.  Online.
  371. Lima, F. B. , Henderson, J. A. , Reddy, A. P. , Hubert, G. W. , Tokuyama, Y. , Kuhar, M. J. , and Bethea, C. L. Unique responses of midbrain CART neurons in macaques to ovarian steroids. Program No.   3.  2008 Neuroscience Meeting Planner.  Society for Neuroscience, Washington D. C. , 2008.  Online.
  372. Rogge, G. A. , Jones, D. C. , Green, T. , Nestler, E. J. and Kuhar, M. J. CREB over expression in the rat nucleus accumbens increases CART peptide levels in vivo.  Program No.   17.  2008 Neuroscience Meeting Planner.  Society for Neuroscience, Washington D. C. , 2008.  Online.

This section on Listing of Abstracts has not been continued.

 

STUDENTS, FELLOWS AND VISITORS

 

Name; Degree, Place and Date of Degree;

Dates and Position in Dr. Kuhar’s Laboratory;

Present Position.

 

Stephanie Dall Vechia Adams; Ph.D., Emory University, 2001;

1996-2001, Graduate Student

Patent agent, King & Spaulding, Atlanta, Georgia

 

Samir F. Atweh; M.D., American University of Beiruit, 1974;

August 1974 ‑ June 1977, Postdoctoral Fellow;

Professor and Head of Neurology,

Faculty of Medicine, American University of Beirut School of Medicine, New York, New York

 

Burcu Balkan; M.D., Ph.D., Ege University, 1994, 2000

August 2001 – August 2002, Visiting Scientist

Professor, Ege University, Izmir, Turkey

 

Stephanie J. Bird; Ph.D., Yale University, 1975;

June 1975 ‑ July 1976, Postdoctoral Fellow;

Special Assistant to the Provost, MIT, Boston, Massachusetts

 

Bruce E. Blough; Ph.D.  University of South Carolina, 1990;

April 1993 – April 1994, Postdoctoral Fellow

Research Scientist, Research Triangle Institute, Research Triangle Park, North Carolina

 

John W. Boja; Ph.D., Northeastern Ohio Universities College of Medicine, 1988;

April 1988 – August 1994, Senior Staff Fellow

Pharmacologist, U.S. Consumer Product Safety Commission

 

Catherine Cerruti; Ph.D., University of Sciences and Techniques of Languedoc, 1991;

November 1992 – December 1994, Visiting Fellow

Research Scientist, INSERM, Paris, France

 

Elizabeth Cline; Ph.D., University of Wyoming, 1990;

July 1, 1990 – May 8, 1992, PRAT Fellow;

Postdoctoral Fellow, University of Colorado, Denver, Colorado

 

Joseph Contrera; Ph.D., New York University, 1966;

January 1975 ‑ August 1975, Visiting Scientist;

Supervisory Pharmacologist, F.D.A., Washington, DC. Retired

 

Pastor Couceyro; Ph.D., Vollum Institute, 1994;

Postdoctoral Fellow and Assistant Research Profesor, 1993-1998

Assistant Professor, Finch University of the Health Sciences, Chicago Medical School, Chicago, Illinois

 

Errol B. De Souza; Ph.D., University of Toronto, 1982;

January 1983 ‑ January 1985, Postdoctoral Fellow;

President and CEO, Biodel, Inc.

 

Geraldina Dominguez; Ph.D., Georgia State University, 1991

February 2000 –September 2002, Research Associate

Program Director, Office of AIDS Malignancy Program, National Institutes of Health, Rockville, MD

 

Annette Fleckenstein, Ph.D., Michigan State University, 1994;

May 1994 – March 1995, Postdoctoral Fellow

Professor, University of Utah, Salt Lake City, Utah

 

Darlene Francis; Ph.D., McGill Univ, Montreal, Canada, 2000

2003-2004, Research Associate

Associate Professor, UC Berkeley, CA

 

J. James Frost; M.D., Ph.D., Washington University, St. Louis, 1994

July 1980 ‑ June 1981, Postdoctoral Fellow;

Consultant, Baltimore, MD.

 

Bridgette E. Garrett; Ph.D., Emory University, 1995;

1997-1998, Research Associate (faculty);

Behavioral Pharmacologist, CDC, Atlanta, Georgia

 

Nicholas E. Goeders; Ph.D., Louisiana State Univ. Medical Center, 1984;

July 1984 ‑ September 1985; Postdoctoral Fellow;

Professor and Chair, Department of Pharmacology, Louisiana State University, Shreveport, Louisiana

 

Ariel Gomez; Ph.D., University of Chile, 1970;

October 1980 ‑ November 1980, Visiting Scientist;

Professor of Neurology, University of Chile, Santiago, Chile (deceased)

 

Wenhe Gong; Ph.D., Emory University, 1995;

1998-1999, Research Associate;

Position in computer industry, Atlanta, GA

 

Walton Hubert; Ph.D., Emory University, 2003

2004-2010, Postdoctoral Fellow

Postdoctoral Fellow, Lab of E.C. Muly, Emory University

 

Richard Hunter; Ph.D., Emory University, 2004;

1999-2004, Graduate Student;

Assistant Professor of Psychology, U Mass, Boston

 

Thomas R. Insel; M.D., Boston University Medical School, 1974;

January 1984 ‑ April 1984, Visiting Scientist;

Director, National Institute of Mental Health, Bethesda, Maryland

 

Jason Jaworski; Ph.D., University of Texas at Austin, 2001;

2001-2004, Postdoctoral Fellow;

Science Adminstrator, Oregon Health Sciences Institute, Portland, Oregon

 

Martin Job; Ph.D., University of Texas, 2009

2009-2013, Postdoctoral Fellow;

Senior Postdoctoral Fellow, Georgia State University

 

Douglas Jones; Ph.D., University of Texas, 2004

2004-2010, Postdoctoral Fellow

Assistant Professor of Pharmacology, Midwestern University, Glendale AZ

 

Andrew R Joyce: Ph.D. UC San Diego,

2003-2006, Project Leader

Chiel Scientific Officer, Venebio Group, LLC

 

Heather L. Kimmel; Ph.D., Emory University, 1997

1997-2001, Postdoctoral Fellow

Assistant Research Professor, Yerkes National Primate Research Center, Emory University

 

Nikolai Klemm; Ph.D., University of Mainz, 1965;

June 1977 ‑ July 1978, Postdoctoral Fellow;

Assistant Professor, University of Constance, Constance, G.F.R.

 

Marie A. Kozel; B.S., Emory University, 2003

2001-2003, Honors Undergraduate Student

MD PhD student, Washington Univ St Louis Med Sch.

 

Ersin O. Koylu; M.D., Ph.D., Anadolu Medical School, Turkey, 1987, 1994;

1995-1997, Postdoctoral Fellow;

Professor, Ege University, Izmir, Turkey

 

Anita Lakatos; M.D., Medical University, Pecs, Hungary, 1995;

1999-2001, Postdoctoral Fellow; 2003-2005, Research Associate

Research Associate, University of California at Irvine

 

Philip Lambert; Ph.D., Royal Postgraduate Medical School, London, 1994;

1996-1998, Senior Postdoctoral Fellow and Assistant Research Professor;

Team Leader, Regeneron, Inc., Tarrytown, New York

 

Herbert Lepor; M.D., Johns Hopkins University, 1979;

October 1982 ‑ October 1983; Postdoctoral Fellow;

Professor and Director of Uro-Oncology, New York University

Medical Center, New York, New York.  1 646 825 6327.

 

Robert Lew; Ph.D., University of Melbourne, 1987;

April 1988 ‑ August 1991; Visiting Foreign Fellow

Research Associate, University of Chicago, Chicago, Illinois

 

Jordan Licata, BS, Emory University 2012

2010 – 2012, Research Assistant

Medical Student, Western University Osteopathic Med Sch, Oregon.

 

Richard Mauer; Ph.D., University of Bern, 1970;

August 1980 ‑ September 1980, Visiting Scientist;

Marketing Division, Sandoz, Ltd., Basel, Switzerland

 

Ilan McNamara;  Ph.D.,  Stony Brook University, 2009

2009-2010, Postdoctoral Fellow

Consultant, Accenture

 

Mark Moffett; PhD., LSU, 2004;

July 2004 – January 2008, Postdoctoral Fellow;

Scientist Contractor, US Army.  Aberdeen MD.

 

Charles Murrin; Ph.D., Yale University, 1975;

August 1975 ‑ August 1978, Postdoctoral Fellow;

Professor of Pharmacology,

University of Nebraska School of Medicine, Omaha, Nebraska, Retired

 

Debra L. Niehoff; Ph.D., Johns Hopkins University, 1983;

September 1978 ‑ January 1983, Graduate Student;

President, Biotext Inc.  New Hope, Pennsylvania; Author

 

Luis Orensanz; Ph.D., Universidad Complutense de Madrid, 1976;

July 1981 ‑ October 15, 1981, Visiting Scientist;

Research Scientist, Universidad Complutense de Madrid, Spain

 

Jose M. Palacios; Ph.D., Universidad Autonoma de Barcelona, 1976;

August 1978 ‑ July 1981, Postdoctoral Fellow;

Director of Research, Laboratorios Almirall, S.A., Barcelona, Spain

 

Amrat Patel; Ph.D., University of Oklahoma, Oklahoma City, 1986;

December 1990 – October 1995, Senior Staff Fellow;

Director of Opioid Program, National Institute on Drug Abuse, NIH, Bethesda, Maryland

 

JoAnna Perry: D.V.M., Virginia-Maryland Regional College Of Veterinary Medicine, 2010

July 2010 – September 2012, Post-doctoral Fellow

Science writer, TRM Oncology, Atlanta, GA

 

Kelly B. Philpot; Ph.D., University of Georgia, 2000;

2001 – May, 2006, Predoctoral Fellow;

Clinical Trials Specialist

 

Nancy Pilotte; Ph.D., Florida State University, Tallahassee, 1977;

June 1987 – March 1994, Staff Fellow;

Branch Chief, National Institute on Drug Abuse, NIH, Bethesda, Maryland

 

Sakire Pögün; Ph.D., Ege University, Izmir, Turkey, 1977;

August 1992 – August 1993, Visiting Scientist;

Professor of Physiology, Ege University School of Medicine, Izmir, Turkey, Retired

 

Mary C. Ritz; Ph.D., University of Minnesota, 1985;

January 1987 ‑ January 1989, Postdoctoral Fellow;

Scientist, University of New Mexico, Albuquerque, New Mexico;

President and CEO, Amethyst Technologies

 

George Rogge, PhD; B.S., Beloit College, 1999

2004-2010, Graduate Student

Postdoctoral Fellow, University of California Irvine

 

Hans Rommelspacher; M.D., University of Berlin, 1968;

May 1973 ‑ September 1974, Postdoctoral Fellow;

Professor and Director, Clinical Neurobiology

University of Berlin, Berlin, Germany

 

John Sharkey; Ph.D., University of Glasgow, 1986;

January 1987 ‑ May 1988, Postdoctoral Fellow;

Senior Lecturer, University of Dundee, Scotland

 

Elias Shaya; M.D., American University of Beirut, 1984;

October 1990 – November 1993, Visiting Scientist;

Private Practice

 

Rabi Simantov; Ph.D., The Weizmann Institute of Science, Israel, 1974;

June 1989 ‑ April 1991, Visiting Scientist;

Professor, The Weizmann Institute of Science, Israel, Retired

 

Jay R. Simon; Ph.D., University of Maryland, 1973;

August 1973 ‑ October 1975, Postdoctoral Fellow;

Professor of Medical Neurobiology,

Indiana University School of Medicine, Indianapolis, Indiana, Retired.

 

Lisa Stanek; Ph.D., Emory University, 2005;

July 1, 2005 – March 31, 2006, Postdoctoral

Genzyme, Cambridge Mass.

 

Roger Summers; Ph.D., University of London, 1968;

May 1982 ‑ September 1982, Visiting Scientist;

Professor and Associate Dean, Monash University, Australia

 

Milt Titeler; Ph.D., University of Toronto, 1978;

1984, Visiting Scientist;

Professor of Pharmacology, Albany Medical College, Albany, New York

 

James R. Unnerstall; Ph.D., Johns Hopkins University, 1984;

September 1979 ‑ October 1984, Graduate Student;

Associate Professor, Department of Anatomy and Cell Biology

University of Illinois at Chicago, Chicago, Illinois

 

Roxanne Vaughan; Ph.D., Virginia Polytechnic Institute, 1985;

1990-1996, Senior Staff Fellow;

Professor University of North Dakota, Grand Forks, North Dakota

 

Aleksandra Vicentic; Ph.D., Loyola University, 2000;

1997-1999, Graduate Student; 2002-2005, Postdoctoral Fellow

Program Director, NIMH, NIH

 

James K. Wamsley; Ph.D., University of Iowa, 1978;

December 1978 ‑ July 1981, Postdoctoral Fellow;

Vice President, Quintiles, Durham, NC

 

Peter J. Whitehouse; M.D., Ph.D., Johns Hopkins University

(M.D., 1975; Ph.D., 1977);

June 1981 ‑ June 1982, Postdoctoral Fellow;

Director, Alzheimers Center, University Hospital of Cleveland, Ohio

 

Nils Wierup, PhD, Uinversity of Lund

Sept 2005, Visiting Scientist

Associate Professor, Neuroendocrine Cell Biology Group

Uinversity of Lund, Sweden

 

Scott Young, III; M.D., Ph.D., Johns Hopkins University

(M.D., 1977; Ph.D., 1980);

September 1977 ‑ April 1980, Graduate Student;

Research Scientist, National Institutes of Health, Bethesda, Maryland

 

Marco A. Zarbin; M.D., Ph.D., Johns Hopkins University

(M.D., Ph.D., 1984);

March 1980 ‑ April 1984, Graduate Student;

Chair, Department of Ophthalmology, New Jersey Medical School

 

TEACHING CONTRIBUTIONS

Teaching Contributions at Emory University (January 1995 to present) as of  November 2015

I am involved in teaching and previously training: Graduate students in the Neuroscience Program and in the Molecular and Systems Pharmacology Program, medical students in the psychiatry and pharmacology courses, post-doctoral fellows and PGY IV residents in the Addictions Psychiatry Program.  I give lectures in other programs as well.

 

Molecular and Systems Pharmacology Graduate Program:

  1. Executive Committee for 3 years.
  2. Director of student qualifying exams, 2 years.
  3. Director of IBS 531, the main Pharmacology course for incoming graduate students, for 3 years.
  4. Lectures in IBS 531.
  5. Involvement in new student interviewing and recruiting.
  6. Mentor for 5 graduate students, the first graduated in 4.3 years. Successful NRSA grants for all 5 students.
  7. Thesis committees for 15 students.

 

Neuroscience Graduate Program:

  1. Mentored rotation students, about 2 per year.
  2. Chair of Nominating Committee for new program directors and committee members, for 6 years.
  3. Thesis committees for 8 students.
  4. Involvement in new student interviewing and recruiting.
  5. Course Director for Frontiers in Neuroscience, a required seminar course for 2 years.
  6. Course Director for IBS 717, Neuropharmacology.
  7. Lectures in Systems Neuroscience Course and in Frontiers of Neuroscience Series.
  8. Executive Committee, 3 years.

 

Medical Students:

  1. Lectures on antidepressant, antipsychotic and Alzheimer’s drugs in the Pharmacology Course.
  2. Lectures on psychostimulants in the Behavioral Neuroscience and Psychiatry Course.
  3. Lectures on Pharmacokinetics in Module 1

 

PGY IV Addictions Psychiatry Program:

  1. Advisor to Program Director since inception of the program.
  2. Lectures on psychostimulants, buprenorphine and drug development to residents and Fellows in Addiction Psychiatry.

 

Postdoctoral Fellows:

  1. Mentor to 15 fellows.
  2. Most obtain individual NRSA grants and travel awards.
  3. All have moved forward in their careers in a timely fashion.

 

Other:  In the role of Senior Scientist and Chief of the Neuroscience Division at Yerkes, I both formally and informally mentored young faculty as well as students and fellows..

  • Lectures in Grants Workshop for Emory faculty and fellows and students.
  • Director of the Institutional NIDA Training Program (2003 – 2014), “The Neurobiology of Drug Abuse”, which provided 10 training slots to our training faculty per year.
  • Ethics lectures on Authorship, Research Misconduct, and Collegial Ethics
  • Lectures to Tibetan monks in the ETSI program in India, 3 conscutive summers (2008-11), on drug Addiction.
  • Lectures to Anesthesiology Associates
  • Development and presentation of a MOOC with Emory and Coursera: “The Addicted Brain”
  • Numerous lectures on ethics and addiction to the community in various forums.

 

PREVIOUS Grant Support for MJ Kuhar

MH25078                                                                              (P.I.: M.J Kuhar)                                   10/01/73 – 09/30/74

National Institutes of Health                                                                                                     $5,000/year D.C.

Regulation of Acetylcholine Synthesis

 

DA00266                                                                               (P.I.: S.H. Snyder)                                07/01/72 – 06/10/77

National Institutes of Health                                                                                                              $45,000/year D.C.

Morphological and Neurophysiological Studies of Central        to M.J. Kuhar

Cholinergic Neurons and Interactions with Opiates

MH25951                                                                              (P.I.: M.J. Kuhar)                                      09/01/74 – 08/31/77

National Institutes of Health                                                                                                                  $40,000/year D.C.

Psychotropic Drugs and Central Cholinergic Mechanisms

 

MH00053                                                                              (P.I.: M.J. Kuhar)                                      03/01/75 – 02/28/80

National Institutes of Health; RCDA Type II Award)      Salary up to $30,000/year

Central Cholinergic Neurons and Psychotropic Drugs

 

MH25951                                                                              (P.I.: M.J. Kuhar)                                      09/01/77 – 08/31/81

National Institutes of Health                                                                                                                  $51,000-57,000/year D.C.

Psychotropic Drugs and Central Cholinergic Mechanisms

 

DA00266                                                                               (P.I.: S.H. Snyder)                                    06/01/77 – 05/31/82

National Institutes of Health                                                                                                                  $45,000-60,000/year D.C.

Anatomical Aspects of Opiate Receptors and Opioid Peptides                                                     to M.J. Kuhar

 

GM07626                                                                              (P.I.: T. August)                                         07/01/78 – 06/30/83

Pharmacology Training Grant

 

NS15080                                                                               (P.I.: H. Wagner)                                      09/01/79 – 08/31/84

National Science Foundation                                                                                                               $9,000/year D.C.

Study of Neuroreceptor Binding in Man                                                                                              to M.J. Kuhar

 

MH25951                                                                              (P.I.: M.J. Kuhar)                                      09/01/81 – 08/31/84

National Institutes of Health                                                                                                                  $70,000/year D.C.

Psychotropic Drugs and Central Cholinergic Mechanisms

 

MH00053                                                                              (P.I.: M.J. Kuhar)                                      03/01/80 – 02/28/85

National Institutes of Health; RCDA Type II Award       Salary up to $30,000/year

Central Cholinergic Neurons and Psychotropic Drugs

 

NS16375                                                                               (P.I.: M. Folstein)                                      07/01/80 – 06/30/85

National Science Foundation                                                                                                               $1,000/year D.C.

Huntington’s Disease Center without Walls                                                                                       to M.J. Kuhar

 

MH15330                                                                              (P.I.: J. Coyle/R.G. Robinson)                07/01/78 – 06/30/86

National Institutes of Health

Interdisciplinary Training Program in Neuroscience

 

DA00266                                                                               (P.I.: S.H. Snyder)                                    06/01/82 – 05/31/87

National Institutes of Health                                                                                                                  $63,000/year D.C.

Johns Hopkins Drug Abuse Center                                                                                                     to M.J. Kuhar

 

GMO7445                                                                             (P.I.: W.J. Lennarz)                                  07/01/82 – 06/30/87

Biochemistry Cellular and Molecular Biology Program Training Grant

 

CTR-4502                                                                             (P.I.: M.J. Kuhar)                                      01/01/97 – 12/31/99

Tobacco Research Council                                                                                                                   $123,314 T.C.

Nicotinic Receptor Compounds as Ligands and Medications

 

Georgia Research Alliance                                               (P.I.:  M.J. Kuhar)                                     07/01/96 – 06/30/00

Eminent Scholar Award (equipment only)                                                                                         $2,400,000  TC

 

DA11178                                                                               (P.I.: M.J. Kuhar)                                     07/01/97 – 06/30/00

National Institutes of Health                                                                                                                 $619,646 T.C.

Cocaine Sensitive Dopamine Transporter Synthesis and Degradation

 

DA11178  Minority Supplement                                       (P.I.: M.J. Kuhar)                                      11/01/97 – 06/30/98

National Institutes of Health                                                                                                                  $21,226 T.C.

Supplement to Cocaine Sensitive Dopamine Transporter Synthesis and Degradation

 

DA05477                                                                               (P.I.: M.J. Kuhar)                                      09/27/96 – 06/30/01

Research Triangle Institute                                                                                                                    $22,000/year D.C.

(Subcontract of NIH Grant to Dr. F.I. Carroll)

Cocaine: A Study of the Biochemical Mechanisms of Action

 

Georgia Research Alliance                                                               (P.I.: M.J. Kuhar)                                    2002-2003

Confocal Microscope Upgrade                                                                                                             $50,000

OND6069                                                                              (P.I.: M.J. Kuhar)                                    9/26/96 – 03/30/03

Counterdrug Technology Assessment Center / Office of Drug Control Policy                        $2,326,230 T.C.

Medications for Drug Abusers

 

Venture grant on gene profiling                                       (P.I.:  M.J. Kuhar)                                     06/01 – 05/03

Yerkes Center Base Grant                                                                                                                     $50,000/year D.C.

Venture grant on CART peptides                                     (P.I.:  M.J. Kuhar)                                     06/01 – 11/02

Center for Behavioral Neuroscience                                                                                                   $13,000 D.C.

Georgia Research Alliance                                               (Co-P.I.: M.J. Kuhar)                                07/01/00 – 06/31/03

New Gene Discovery (equipment only)                                                                                              $2,400,000 over 3 years

DA10732 (supplement)                                                     (P.I.: M.J. Kuhar)                                      01/15/98 – 04/30/03

National Institutes of Health, NIDA                                                                                                      $56,000/year T.C.

Theoretical Modeling of Drug Dependence

DA10732 (supplement)                                                     (P.I.: M.J. Kuhar)                                      09/27/02 – 04/30/04

National Institutes of Health, NIDA                                                                                                      $68,406/year T.C.

CART and the Stress Response

 

DA10732                                                                               (P.I.: M.J. Kuhar)                                      01/15/98 – 07/14/07.

National Institutes of Health, NIDA                                                                                                      $2,570,713 T.C.

CART: A Novel Cocaine Regulated Neurochemical

 

MH58922                                                                              (P.I.:  C. Nemeroff)                                 09/30/99 – 08/31/04

National Institutes of Health, NIMH                                                                                                     $100,000/year T.C.

Monoaminergic Receptors and Maternal Separation

 

Georgia Research Alliance                                               (Co-P.I.: M.J. Kuhar)                                07/01/03 – 06/30/04

Adipose Tissue Apoptosis in the Treatment of Obesity                                                                                $10,000/year T.C.

 

K05 DA00418                                                                      (P.I.: M.J. Kuhar)                                      04/01/99 – 03/31/09

National Institutes of Health, NIDA                                                                                                      $1,160,526  T.C.

Mechanisms of Drugs of Abuse

 

Contract # 639245PFIZER                                                 (PI: M.J. Kuhar)                                        12/01/07 – 12/31/08

Pfizer                                                                                                                                                         $319,000 Total Costs

The CART Receptor

 

RO1 NS055015   (RO1)                                                    (Co-PI: M.J. Kuhar)                                 12/01/06 – 11/30/11

National Institutes of Health                                                                                                                 $20,000/ year D.C.

CART Regulation of Wakefulness

 

RO1 DA015162 (RO1)                                                        (PI: M. J. Kuhar)                                       05/01/02 – 08/31/12

National Institutes of Health, NIDA                                                                                                      $2,291,682  T.C

Promoter Characterization of the CART gene

 

DA015040 (a T32)                                                              (P.I.: M.J. Kuhar)                                      07/07/03 – 06/30/14

National Institutes of Health, NIDA                                                                                                      $3,623,383  T.C.

Training Program in Neurobiology of Drug Abuse

 

 

INDIVIDUAL NRSA SUPPORT WITHIN DR KUHAR’S LAB SINCE ‘99

 

F32 DA005935                                                                    (P.I.:  H.L. Kimmel)                                  08/01/99 – 07/31/02

National Institutes of Health, NIDA                                                                                                      $38,772/year D.C.

Cocaine-Induced Changes in the Dopamine Transporter

 

F31 DA06044                                                                       (P.I.: S.E. DallVechia)                             09/01/00 – 08/31/02

National Institutes of Health, NIDA                                                                                                      $33,702/year D.C.

CART Peptide Localization in Accumbal and Nigral Pathways

 

F31 DA017433                                                                    (P.I.: K Philpot)                                        11/01/03 – 10/31/05

National Institutes of Health, NIDA                                                                                                   $24,418/year D.C.

Characterization of CART-Containing Neurons in the Lateral Hypothalamus       

 

F32 DA15593-01                                                 (P.I.: A. Vicentic)                                                   05/28/02 – 05/27/05

National Institutes of Health, NIDA                                                                                                      $44,212/year D.C.

Identification of Cocaine-Regulated Gene

 

F31 DA15277-01A1                                                            (P.I.: R.G. Hunter)                                     10/01/02 – 09/30/04

National Institutes of Health, NIDA                                                                                                      $22,606/year D.C.

CART and the Dopamine System in the Nucleus Accumbens

 

F32 DA15279-01A1                                                            (P.I.: J.N. Jaworski)                                  10/01/02 – 09/30/05

National Institutes of Health, NIDA                                                                                                      $43,854/year D.C.

Psychostimulant-Like Effects of CART Neuropeptides

 

F32 DA020312                                                                    (P.I.: D Jones)                                           9/1/05 – 8/31/08

National Institutes of Health, NIDA                                                                                                      $43,976/year T.C.

CART regulation in vivo in the rat Nucleus Accumbens

 

F32 DA                                                                                  (P.I.: W Hubert)                                         11/01/06 – 10-31/08

National Institutes of Health, NIDA                                                                                                      $43.976/year T.C.

CART peptide containing pathways in the Nucleus Accumbens.

 

F31 DA021970                                                                    (P.I.: G Rogge)                                          10/31/06 – 09

National Institutes of Health, NIDA                                                                                                      $28,152/year T. C.

Regulation of the CART gene by promoter cis-elements.

 

INTRAMURAL FUNDING  (1985-1995)

During the 10-year period, Dr. Kuhar was Chief of the Neuro­science Branch at NIDA where the budget varied from (personnel and consumables) approxi­mately $1,000,000 to $5,000,000 per year.  Dr. Kuhar’s personal research group, which was a section within the

Branch, had a budget of, for example in 1995,  $1,168,000 for personnel, equipment, overhead and supplies

PRIVATE FUNDING

Pfizer

CART Receptor                                                                                                                                                             $300,000.

 

Hoffmann-La Roche                                                                                                                                                           $970

Light Microscopic Autoradiographic Localization of Drugs

 

Lederle Laboratory                                                                                                                                                       $2,599.71

Anxiolytics and Localizing Benzodiazepine Receptors in Brain at Microscopic Levels

 

McKnight Foundation                                                                                                                                                 $26,393.23

Neurotransmitter Disposition and Basic Mechanisms Underlying Learning and Memory

 

McKnight Foundation                                                                                                                                                 $17,448.84

Neurotransmitter Disposition and Basic Mechanisms Underlying Learning and Memory

 

The Upjohn Company                                                                                                                                                        $2,609

The Neurochemistry of Benzodiazepines

 

Huntington’s Disease Fund, Estate of Lena Marcus                                                                                                    $2,000

 

Solvay Pharmaceuticals                                                                                                                                                    $18,000

Lithium Effects on Brain Metabolism

 

(about $20 million brought into Emory as of Jan 2013)